ID A0A091DYZ8_FUKDA Unreviewed; 334 AA.
AC A0A091DYZ8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Double C2-like domain-containing protein alpha {ECO:0000313|EMBL:KFO36282.1};
GN ORFNames=H920_02270 {ECO:0000313|EMBL:KFO36282.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO36282.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO36282.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO36282.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN121508; KFO36282.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091DYZ8; -.
DR STRING; 885580.ENSFDAP00000003799; -.
DR eggNOG; KOG1013; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04035; C2A_Rabphilin_Doc2; 1.
DR CDD; cd08384; C2B_Rabphilin_Doc2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR043566; Rabphilin/DOC2/Noc2.
DR InterPro; IPR047022; Rabphilin_Doc2_C2A.
DR InterPro; IPR001565; Synaptotagmin.
DR PANTHER; PTHR45729:SF1; DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN ALPHA; 1.
DR PANTHER; PTHR45729; RABPHILIN, ISOFORM A; 1.
DR Pfam; PF00168; C2; 2.
DR PRINTS; PR00360; C2DOMAIN.
DR PRINTS; PR00399; SYNAPTOTAGMN.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..120
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 185..307
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 334 AA; 37012 MW; B711E80CDA70EBE0 CRC64;
MLEFDLLYDP ASCTLHCSIL RAKGLKPMDF NGLADPYVKL HLLPGACKAN KLKTKTQRNT
LNPVWNEDLT YSGITEEDIS HKVLRISVCD EDKLSHNEFI GEIRVPLRRL KPSQKKHFNI
CLERQVPVRG SCGDACGEAG GQVARTSSLS PQLASPSSMS AALRGISCYL KELEQAEQGP
GLLEERGRIL LSLSYSSQRR GLLVGIVRCA HLAAMDVNGY SDPYVKTYLR PDVDKKSKHK
TCVKKKTLNP EFNEEFFYEI ELSTLATKTL EVTVWDYDIG KSNDFIGGVS LGPAARGEAQ
RHWSDCLQQP GVALERWHTL TSELPPAAGT LPLA
//
