ID A0A091E3V7_FUKDA Unreviewed; 793 AA.
AC A0A091E3V7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Vomeronasal type-2 receptor 26 {ECO:0000313|EMBL:KFO38042.1};
GN ORFNames=H920_00553 {ECO:0000313|EMBL:KFO38042.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO38042.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO38042.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO38042.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TCTP family. {ECO:0000256|PROSITE-
CC ProRule:PRU01133}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN120637; KFO38042.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091E3V7; -.
DR STRING; 885580.ENSFDAP00000010121; -.
DR eggNOG; KOG1056; Eukaryota.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06365; PBP1_pheromone_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR011057; Mss4-like_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR034737; TCTP.
DR InterPro; IPR018103; Translation_control_tumour_CS.
DR InterPro; IPR018105; Translational_control_tumour_p.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF547; VOMERONASAL 2, RECEPTOR 118-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR Pfam; PF00838; TCTP; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF51316; Mss4-like; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
DR PROSITE; PS01002; TCTP_1; 1.
DR PROSITE; PS51797; TCTP_3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFO38042.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 525..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 558..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..652
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 680..703
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 715..735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 747..770
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..187
FT /note="TCTP"
FT /evidence="ECO:0000259|PROSITE:PS51797"
FT DOMAIN 521..785
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 47..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 793 AA; 89201 MW; EB3F36BDA1AD5FC0 CRC64;
MIIFWDLISH NEMFSDIYKI RETASGLCLE VEGKTVSRME GNIDDSLIGG NASAEGPEGK
GQDEVPNYTC RRESKSIAVL TGTTWEISAQ IGTLLELYKF PQMTYGAFDP MLSDSDQFPS
LYQMAPKDTS LALGMVSLVL HFSWTWVGLV IAENQKGLQF LSDLREEMDR NRICVSFLKM
ISKSDMVSNR PTYDLWTRET SPANVIIIYF DTNSVLDVGF YTGQHLVTWR VWVTNSQWHP
ATLGENFIMD SFHGTLIFAH QHEEISGFKT FIQTVTPSKY PEDIYLTVFW SMNFDCTLSN
FDCTLKNCPP NASLTYLPVS HFDPAMSDES YNVYNAVYAV AHALHKMLLY QVQMQPSNIG
EPEGFSPWQL HHFLKELQFT SPIGDHVNLD EQKKLSAEYD ILNFWNLPEG LRLKMKVGRF
SPHAPRSQQL SLNEDIIEWG TGITETPRSV CSESCHPGFR KSPQEGRAAC CFNCIPCPEN
EISNETDMQQ CLKCPGHQYS NIQRNRCLQK SVTFLAFEDP LGKTLVGTAL SLAILTAVVL
GLFVKHRDTP MVKANNRTLS YTLLISLIFC FLCSLLFIGL PNTATCILQQ TTFGIVFTVA
VSTILAKTIT VVLAFKVTAP GRRMRQLLVL GAPNYIIPIW SMIQLTLCGV WMGTSPPYID
TDAHSEHGHI IIVCNKGSLT AFYCVLGYLG SLALVSFTLA FLARNLPDTF NEAKFLTFSM
LLFCSVWVTF LPVYHSTKGK VMVAMEVFSI LASSAGLLAC IFIPKCYIIL LRPDRNSLHG
FRDKTHSDRK KIF
//
