ID   A0A091E8K1_CORBR        Unreviewed;      1013 AA.
AC   A0A091E8K1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-1 {ECO:0000313|EMBL:KFO52834.1};
DE   Flags: Fragment;
GN   ORFNames=N302_11976 {ECO:0000313|EMBL:KFO52834.1};
OS   Corvus brachyrhynchos (American crow).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC   Corvus.
OX   NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO52834.1, ECO:0000313|Proteomes:UP000052976};
RN   [1] {ECO:0000313|EMBL:KFO52834.1, ECO:0000313|Proteomes:UP000052976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO52834.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the calcium channel subunit alpha-2/delta
CC       family. {ECO:0000256|ARBA:ARBA00007060}.
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DR   EMBL; KK717868; KFO52834.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091E8K1; -.
DR   STRING; 85066.A0A091E8K1; -.
DR   Proteomes; UP000052976; Unassembled WGS sequence.
DR   GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   CDD; cd01463; vWA_VGCC_like; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR013680; VDCC_a2/dsu.
DR   InterPro; IPR013608; VWA_N.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10166; VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED; 1.
DR   PANTHER; PTHR10166:SF6; VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1; 1.
DR   Pfam; PF08473; VGCC_alpha2; 1.
DR   Pfam; PF00092; VWA; 1.
DR   Pfam; PF08399; VWA_N; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022673};
KW   Calcium channel {ECO:0000256|ARBA:ARBA00022673};
KW   Calcium transport {ECO:0000256|ARBA:ARBA00022673};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022882};
KW   Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT   DOMAIN          157..334
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          29..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..50
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO52834.1"
FT   NON_TER         1013
FT                   /evidence="ECO:0000313|EMBL:KFO52834.1"
SQ   SEQUENCE   1013 AA;  114933 MW;  DE137920A162D763 CRC64;
     QRLAKEAEKY QASHQWRDEF GNNDIIYYNA KDDQNDPEKN ETESGSQRIR PVFEDDPVFR
     RQTSYQHAAV HIPTDIYEGS TIVLNELNWT AALDDVFKRN REEDPTLLWQ VFGSATGLAR
     YYPASPWVDK SRTPNKIDLY DVRRRPWYIQ GAASPKDMLI LVDASGSVSG LTLKLIRTSV
     IEMLETLSDD DFVNVVSFNN NAQNVSCFNH LVQANVRNKK KLKEAVYKIS AKGITDYKKG
     FSYAFEQLLN HSVSRANCNK IIMLFTDGGE ERAQEIFHKY NEDKKVRVFT FSVGQHNYDK
     GPIQWMACEN KGYYYEIPSI GAIRINTQEY LDVLGRPMVL AGEQAKQVQW TNVYLDALEL
     GLVITGTLPV FNLTREQNGK INQLILGVMG VDVSLEDIKK LTPRFTLCPN GYYFAIDPNG
     YVLLHPNLQP KQIGVGIPKV KLRKRRPNVQ NPKSQEPVTL DFLDAELEND IKVEIRKKMI
     DGESGEKTFE TLVKSQDERY IDKGNRTYTW TAVNGTDYSL ALVLPSYSFY YIKAKIDEPI
     TQARCKYCKG SLVLSESLKL DHFDEAGYTF LAPRDYCNDV KKSENNTEFL LNFNEFIDRN
     TPSSSSCNTD MVIRVLLDAG FTNELAQNYW SKLSLDGVVA QFVVTDGGIT RVFPKRAGED
     WLENAETYEV SFYKRSLDND NYIFTAPYYN KSGANSYESG IMVSKAVEIE IDGKLLKPAV
     VGIKIDATSW MENFTKTTIK SLCNSEICGC ERNSMHVDCV ILDDGGFLLM SNRDEYTQQI
     GRFFGEIDPG LMRNLINMSL YAFNKSYDYQ SVCDPEEEPK QGAGLRSAYV PTITDILQLG
     WWASAAAWSI LQQLFLSLTF PRFLEAADME DDDFGAALPK TSCITEQTQY FFENNDKSFG
     GIVDCINCSR LYHAEKISNT NLVFIISDSQ LLCRSCDPKP LMQAEKPDEG PNPCEMVKQP
     RYRKGPEICF DEAKQEDSAD CGGASGLSPS LWSMVPIQLV LLWLLSGSRH CQL
//