ID A0A091E9N7_FUKDA Unreviewed; 346 AA.
AC A0A091E9N7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Ankyrin repeat and SOCS box protein 6 {ECO:0000313|EMBL:KFO31921.1};
GN ORFNames=H920_06672 {ECO:0000313|EMBL:KFO31921.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO31921.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO31921.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO31921.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN122233; KFO31921.1; -; Genomic_DNA.
DR RefSeq; XP_010625653.1; XM_010627351.2.
DR AlphaFoldDB; A0A091E9N7; -.
DR STRING; 885580.ENSFDAP00000012000; -.
DR GeneID; 104864422; -.
DR CTD; 140459; -.
DR eggNOG; KOG0504; Eukaryota.
DR OrthoDB; 5352456at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03725; SOCS_ASB6; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037327; ASB6_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24132; ANKYRIN REPEAT AND SOCS BOX PROTEIN 6; 1.
DR PANTHER; PTHR24132:SF24; ANKYRIN REPEAT AND SOCS BOX PROTEIN 6; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 4.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT REPEAT 27..59
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 61..94
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 285..340
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 346 AA; 38390 MW; ED378E9131C54143 CRC64;
MAELGLTRAA AILLCSGANL NFEDPVTYYT ALHIAVLRNQ PDMVELLVRH GADINRRDRI
HESSPLDLAS EEPERLPCLQ RLLELGADVN AADKHGKTAL LHALASSDGV QVHNTDNIRL
LLEGGADVKA TTKDGDTVFT CIIFLLGETV GGDEEEARMI NRFCFRVAQL LLEHGADPSE
CPAHESLMHI CLKSFKLHFR LLRFLLESGA AYNCSLHGAS CWSGFHIIFE RLCSHPGCAE
DESHADLLRK AETVLDLMVT NSRRLQLPAN FDVHPVGSLA DKIQALHQSL RQLELRPPAL
KHLCRVSIRL HLQPWPVDTK VKALPLPDRL KWYLLSEHSG VGEDDG
//
