ID A0A091EGY5_CORBR Unreviewed; 327 AA.
AC A0A091EGY5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=glycine hydroxymethyltransferase {ECO:0000256|ARBA:ARBA00012256};
DE EC=2.1.2.1 {ECO:0000256|ARBA:ARBA00012256};
DE Flags: Fragment;
GN ORFNames=N302_04740 {ECO:0000313|EMBL:KFO55912.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO55912.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO55912.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO55912.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion.
CC {ECO:0000256|ARBA:ARBA00004777}.
CC -!- SIMILARITY: Belongs to the SHMT family.
CC {ECO:0000256|ARBA:ARBA00006376}.
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DR EMBL; KK718384; KFO55912.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091EGY5; -.
DR STRING; 85066.A0A091EGY5; -.
DR UniPathway; UPA00193; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019264; P:glycine biosynthetic process from serine; IEA:InterPro.
DR GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR001085; Ser_HO-MeTrfase.
DR InterPro; IPR019798; Ser_HO-MeTrfase_PLP_BS.
DR InterPro; IPR039429; SHMT-like_dom.
DR PANTHER; PTHR11680; SERINE HYDROXYMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR11680:SF65; SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF00464; SHMT; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00096; SHMT; 1.
PE 3: Inferred from homology;
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..271
FT /note="Serine hydroxymethyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF00464"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO55912.1"
FT NON_TER 327
FT /evidence="ECO:0000313|EMBL:KFO55912.1"
SQ SEQUENCE 327 AA; 35757 MW; 4E047F686E1B791A CRC64;
SLTHGYMTDV KRISATSIFF ESMPYKLDPA TGLIDYAQLE VTARLFRPRL IIAGTSAYAR
LIDYARIKRG HGEGPGAGGG LVAAKAIPSP FEHADVVTST THKTLRGARS GLIFYRKGVR
SVDKKTGKET LYDLEDRINF SVFPSLQGGP HNHAIAAVAV ALKQASSPAF QEYCQQVLRN
AKAMAQALLQ RGYTLVSGGT DNHLVLVDLR PKGIDGARAE RVLELVSIPA NKNTCPGDKS
ALTPGGLRLG APALPSRQFR EEDFQKVVEF IDEGITLALD VKSKTSKLQD FKTFLLQDSE
TQQRLSNLRQ RVETFARAFP MPGFSDH
//
