ID A0A091EH54_CORBR Unreviewed; 172 AA.
AC A0A091EH54;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Diamine acetyltransferase 1 {ECO:0000256|ARBA:ARBA00017209};
DE EC=2.3.1.57 {ECO:0000256|ARBA:ARBA00013209};
DE AltName: Full=Polyamine N-acetyltransferase 1 {ECO:0000256|ARBA:ARBA00031435};
DE AltName: Full=Putrescine acetyltransferase {ECO:0000256|ARBA:ARBA00029790};
DE AltName: Full=Spermidine/spermine N(1)-acetyltransferase 1 {ECO:0000256|ARBA:ARBA00031532};
DE Flags: Fragment;
GN ORFNames=N302_01106 {ECO:0000313|EMBL:KFO55739.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO55739.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO55739.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO55739.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + an alkane-alpha,omega-diamine = an N-
CC acetylalkane-alpha,omega-diamine + CoA + H(+); Xref=Rhea:RHEA:11116,
CC Rhea:RHEA-COMP:9766, Rhea:RHEA-COMP:9767, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:70977,
CC ChEBI:CHEBI:70988; EC=2.3.1.57;
CC Evidence={ECO:0000256|ARBA:ARBA00023565};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:11117;
CC Evidence={ECO:0000256|ARBA:ARBA00023565};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + spermidine = CoA + H(+) + N(1)-acetylspermidine;
CC Xref=Rhea:RHEA:28150, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288, ChEBI:CHEBI:57834, ChEBI:CHEBI:58324; EC=2.3.1.57;
CC Evidence={ECO:0000256|ARBA:ARBA00023509};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:28151;
CC Evidence={ECO:0000256|ARBA:ARBA00023509};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + spermine = CoA + H(+) + N(1)-acetylspermine;
CC Xref=Rhea:RHEA:33099, ChEBI:CHEBI:15378, ChEBI:CHEBI:45725,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:58101; EC=2.3.1.57;
CC Evidence={ECO:0000256|ARBA:ARBA00023533};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:33100;
CC Evidence={ECO:0000256|ARBA:ARBA00023533};
CC -!- PATHWAY: Amine and polyamine degradation; putrescine degradation; N-
CC acetylputrescine from putrescine: step 1/1.
CC {ECO:0000256|ARBA:ARBA00004995}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00008694}.
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DR EMBL; KK718327; KFO55739.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091EH54; -.
DR STRING; 85066.A0A091EH54; -.
DR UniPathway; UPA00188; UER00363.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0004145; F:diamine N-acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009447; P:putrescine catabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR PANTHER; PTHR10545:SF36; DIAMINE ACETYLTRANSFERASE 1; 1.
DR PANTHER; PTHR10545; DIAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51186; GNAT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Transferase {ECO:0000313|EMBL:KFO55739.1}.
FT DOMAIN 5..171
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO55739.1"
FT NON_TER 172
FT /evidence="ECO:0000313|EMBL:KFO55739.1"
SQ SEQUENCE 172 AA; 20025 MW; A8A149953D61FE16 CRC64;
KMASFSIRAA RPEDCPDLLR LIKELAKYED MEDQVVLTEK ELLEDGFGEH PFYHCLVAEV
PKDQWSSGET CVVGFAMYYF TYDPWIGKLL YLEDFYVMAE YRGLGIGSEI LKNLSQVAVK
CRCSSMHFLV AEWNEPSIRF YKRRGASDLS TEEGWRLFKI DKEYLLKMAA EE
//
