ID A0A091EQZ7_FUKDA Unreviewed; 376 AA.
AC A0A091EQZ7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=PH and SEC7 domain-containing protein 3 {ECO:0000313|EMBL:KFO38156.1};
GN ORFNames=H920_00551 {ECO:0000313|EMBL:KFO38156.1};
OS Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Fukomys.
OX NCBI_TaxID=885580 {ECO:0000313|EMBL:KFO38156.1, ECO:0000313|Proteomes:UP000028990};
RN [1] {ECO:0000313|EMBL:KFO38156.1, ECO:0000313|Proteomes:UP000028990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Liver {ECO:0000313|EMBL:KFO38156.1};
RA Gladyshev V.N., Fang X.;
RT "The Damaraland mole rat (Fukomys damarensis) genome and evolution of
RT African mole rats.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN120636; KFO38156.1; -; Genomic_DNA.
DR RefSeq; XP_010623299.1; XM_010624997.1.
DR AlphaFoldDB; A0A091EQZ7; -.
DR Ensembl; ENSFDAT00000010869; ENSFDAP00000021601; ENSFDAG00000007589.
DR GeneID; 104862749; -.
DR CTD; 23362; -.
DR OMA; NLSGMMD; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000028990; Unassembled WGS sequence.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR CDD; cd13295; PH_EFA6; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041681; PH_9.
DR InterPro; IPR001605; PH_dom-spectrin-type.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF337; PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF15410; PH_9; 1.
DR PRINTS; PR00683; SPECTRINPH.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028990}.
FT DOMAIN 113..226
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..89
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..376
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 42445 MW; E5477B4084D8D78C CRC64;
MIGVNSVQSA SKVRVRTSGS VKYSREDSIR RQSHRSKSMK ISNSSEFSAK ETKALYNSIK
NEKLEWAVDD EEKKKSPSEG TDEKANGTHP KTISRIGSTT NPFLDIPHDP NAAVYKSGFL
ARKIHADMDG KKTPRGKRGW KTFYAVLKGT VLYLQKDEYK PEKALSEEDL KNAVSMHHAL
ASKATDYEKK PNVFKLKTAD WRVLLFQTQS PEEMQGWINK INCVAAVFSA PPFPAAIGSQ
KKFSRPLLPA TTTKLSQEEQ LKSHESKLKQ ITTELAEHRS YPPDKKVKAK DVDEYKLKDH
YLEFEKTRYE TYVSILKEGG KQLLSHDENE AAGLKKSHSS PSLNPDSSPI TAKVKRNVSE
RKDHRPETPS IKQKVT
//
