ID A0A091F037_CORBR Unreviewed; 5429 AA.
AC A0A091F037;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Dystonin {ECO:0000313|EMBL:KFO62187.1};
DE Flags: Fragment;
GN ORFNames=N302_02565 {ECO:0000313|EMBL:KFO62187.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO62187.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO62187.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO62187.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR EMBL; KK719242; KFO62187.1; -; Genomic_DNA.
DR STRING; 85066.A0A091F037; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21239; CH_DYST_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 17.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 32.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF23; SHORT STOP, ISOFORM H; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 21.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21019; Spectrin_3; 1.
DR Pfam; PF21020; Spectrin_4; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01129; DELLA; 1.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00150; SPEC; 33.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 27.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51460; GAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..89
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 102..216
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 848..905
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 5055..5090
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 5091..5126
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 5131..5210
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 2951..2976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5215..5235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5253..5310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5339..5429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 695..729
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1169..1203
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1379..1407
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1606..1665
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1771..1840
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2192..2266
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2442..2469
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2656..2717
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2806..2833
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3091..3160
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3620..3660
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4079..4106
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4195..4229
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4335..4369
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4840..4867
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2951..2973
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5220..5235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5269..5304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5345..5366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5373..5399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO62187.1"
FT NON_TER 5429
FT /evidence="ECO:0000313|EMBL:KFO62187.1"
SQ SEQUENCE 5429 AA; 621703 MW; 4FD03EE2F2FE1E2D CRC64;
VQVRKHVNDL YEDLRDGHNL ISLLEVLSGD TLPREKGRMR FHRLQNVQIA LDYLKKRQVK
LVNIRNDDIT DGNPKLTLGL IWTIILHFQI SDIHVTGESE DMSAKERLLL WSQQTTEGYA
GIHCENFTTC WRDGRLFNAI IHKYRQVLCL LPWKMPDLID MSTVAVQSNL ANLEHAFFVA
EKLGVARLLD PEDVDVSSPD EKSVITYVSS LYDAFPKVPE GGEGISANDV EVKWVEYQNM
VNYLMQWIRH HVTIMSDRTF PNNPVELKAL YNQYLQFKET EIPPKETDKS KIKHLYKLLE
VWIEFGRIKL SQGYHPNDIE KEWGKLIIAM LEREKTLRPE VERLEMLQQI ANRIQRDSRS
CEDKLILARN ALQSDTKRLE SGLQFQHEAE IAGYLLESEN LLRQQVIDAQ ILIDGKYYQA
DQLVQRVAKL RDELMAIRTE CSSVYNKGHT LTTEQTKLMI SGITESLNSG FTTNLTPELN
AAMTQGLTPT LTSSSLTSGL SSGLTSRLTP TITPTYPPGI PPRLIQSYVT GVDSGALQTL
KLMQIRKPLM KSAFVDQNLT EEEVNMKFVQ DLLSWVEEMQ VQLDRAEWGS DLPSVESHLE
NHKNVHKAIE EFESSLKEAK ISEIQMTAPL KLSYTEKLHK LESQYSKLLN TSRNQERHLD
TLHNFVSRAT RELIWLNEKE EEEVAYDWSE RNPNIARKKE YHAELMRELD EKEEVIKSVQ
EIAEQLLLEN HPARLTIEAY RAAMQTQWSW ILQLCHCVEQ HLRENAAYFE FFSDAKEAME
YLKNLKDTIY RKYSCDRSSS LHRLEDLVQE SMEEKEQLLQ YKSTVAGLVG RAKAIIQLKP
RNPDCVLKTS IPIKAICDYR QIEITIYKDD ECVLANNSHR AKWKVISPSG NEAMVPSVCF
TVPPPNKEAI DTANRIEQQF QNVLALWHES HVNMKSVVSW HYLTNEIEAV RAGNVASIKT
MLPGEHQQVL SNLQSRFDDF VEDSQESKIF TSSDTAQLER EVNVCKQYYQ ELLKSAEREE
QEESIYNLYI SEVRNIRLRL ESCEERLIRQ IRTPMERDDV HENVLRISEQ EKLKKELDRL
KDDLGIITDK CEEFFSQAAG SPSVPTLRSE LNVVIQNMNQ VYSMSSIFID KLKTINLVLT
NTQTAESLVK QYETKLCEEE AVTADKNNIE NLMGTLKQWR SEVDEKRQTF HALEDELQKA
KMISDQMFKM HKERDLDFDW HKEKVDQLAE RWQNVHSQIE NRLRDLEGIN KSLKYYKDTY
NSLDTWIQQV EDTQRKIQEI HPENSKALAK QLNQHKMLVS EIEMKQSKID ECQKYSEQYS
AAVKDYELQT MTYRAMVDSQ QKSPVKRRRM QSSSDFIIQE FMDLRTRYTA LVTLMTQYIK
FAGDSLKRLE EEEKSVEEEK KEHVEKAGDL LKWVSNLSKT LGKEEGEKAE KTDLPKQQIS
LHEMSTKKEQ IAEALQTTQS FLAKHSDKMT DEERNEMEKQ VRSLQESYSL LSNEALKQLQ
EVHLGDEKME EKAVAERQHE CKEKLQEICD LLTQTENRLI GQQESLVIGD SKAELEQYQT
KQEEIQKDMR TSAQTLAEIV KNTETFLKEN GEKLSQEDKT VLEQKLNEAK TKCLLLSQKA
EESKKELDKA MTTAIKQETE KVAAIEQLEE SKNTIENLLD WLSNVDKEAE HGRKFKQVIE
QNGTHFEERD VKVLEGEEDD VNGNLLEMQQ DIETRVDGLV KSTDDNLNQQ YQKVKAQHEK
IISQQQAIIV ATQSAQALLE KQGHYLTPEE KDKMQRNMKE LKAQYETALA ESERKMKLTH
SLREELEKFD ADYSEFETWL QQAEQELDNL EAGASDFSGI MVKLKRQKSF SEDVISHKGD
LRYITISGQR VLDAARSCSK RDGVKVDKDG IDTSATYAEV QNKLDRASDR FKSLYTKCSI
LGNNLKDLVD KYQHYEDASS GLLSGLQASE IAVNKQLSEP IAVDPKNLQR QLEETKVLQG
QVSNHQIAVE KLKKAAEVLL DTRGELTPDK DEIQKTLDDI VERYDNLSKS VNERNEKLQV
TLTRSLSVQD GLDEMLDWME GVEKSLKEQD QVPLNSAAIQ DIISKSIMLE QDIAGRQSSI
NTMNEKVKKF METADPSTAS TLQAKMSELS GRFSEASNKH REKLMKMEEL KTKVELFEGL
SEKLQSFLDE KNQALSETEA PRKDVSEVSQ YMQEASVELA QHKKDLEVLK KLLEELSFHA
LPGDKALVLE KVNALSKKFK EVEETIKEKE EDVSSCQKEM DTFELLVESL KKWIKETTER
IPAAQPSLNT EELKKPLEDT LNLKDEWTLK APELQKMNSR GTLLCNLITA VTSPAKLRAV
AKSGGTILNG EGGAPGTQDF LKNKELTTVQ QAMSNVNHSY EDLGVLLNEK ISELESMLSK
MQNIQEESAS MMHWLQKMDK TASDWEAAPT DSEAVKAQVE QHKLFETELK QSANKVQELK
DKVTELLEKN PDSPEAPKWR QTLDKIDSKW KELNQVTSER QQKLEESSNY LTQFQTAEAQ
LKHWLVEKEL MVSVLGPLSI DPNMLNTQKQ QVQILLKEFD TRKPQYEQLT MAGEGILERP
GEHPPSHEIV KEQLAAVAQK WDSLTSQLKK RCERIDLAIV KSIEYQSLLR SLSDKLSALD
SKLSSSLAVS TQPDAVKQQL EIAKEMKEEI EQEMKNINAA QALCEELSTL VGEEYLKAEL
TRQLDGILKS FKDIEQKSDN HVQQLQSAYA TSHQFQQMSK DFQAWISKKK EELNQARPVS
AKLDVLQSLI EEQKDFTKTM SSQISSYERI VAEGESILQK TQGADKTELQ SQIAILKNNW
EEMNKQVKER EDKLADCLEK ALKYKQHVEN LQPWIEKCQS NLYELKVGIN PVEIEDSIVQ
VRAWQKDLDK HHGMVELLNN SAESLLSASQ TDKEIVEEET KKLNQNVKVV TEELHKKRDC
LENMAQRLKE FQDSSRETER QLRSAKEHLE AHDSLGPQSF SNKHLTMMQA QQKALQALKP
HVDLAKKLAQ DLVVEASDSA GVSDLLLQAE SLEQEYTAVK QQVEDRCSFL ETKLQGIGHF
QNSIREMFSQ FAEFDDELDS MAPVGRDVNV LQSQREDIKH FMKKLEDLIM NNENANKNCK
IMLATEAEAS PDLVGIKRDL EALNKQCNKL LDRAKAREDQ VDGTICRVEE FYSKLKEFST
LLGRAEEHEE SQGPVGMETE AINQQLNTFK VFQKEEIEPL QVKQQEVNWL GQGLIQSAAK
STNTENLEHD LEDVNTRWKT LNKKVAQRAA QLQEALLHCG RFQDALESLL SWLIDTEDLV
ANQKPPSAEF KVVKAQIQEQ KLLQRLLDDR KPTVEAIKRE GEKIAESAEP ADRVKILKQL
SFLDSRWDAL LSKAETRNRQ LEGISVVAQQ FHEALEPLVE WLTATEKRLA NAEPIGTQAS
KLQQQISQHK ALEDDVLAHN KSLHQAISAG QSLKTMSSRE DKDMVQEKLD SAQARYIEIQ
EKSNSRCELL QQAYSNAQIF GEDEVELMNW LNEIHDKLNK LSVQDCNTEL LEKQHSELLD
LQEEILLRKQ SVDLAIQNGL ELLKQTTGDE VVIVQDKLEG IKARYKDITK LSSDVSKTLE
QALQLAGQLH STHEELCKWL DEVEMELLSY ETQVPKAEEL SQVQERQKEL KKEAKNNKGL
LDSLNEVGSA FLELVPWRAR EGLDKMITED NERYRLVSDT ISQKVDEIDA AILRSQQFDQ
AADAEFAWIA ETEKKLMSLG DIRLEQDQTT AQLQVQKAFT MEILRHKDTI DELVKSGDKL
MKTCTEEEKQ MMKKKIESLL QKYDAVCQMN SERNLQLERA QSLVNQFWET YEELWPWLTE
TEMIISQLPA PALEYETLKQ QQEEHRQLRE LIAEHKPHID KMNKTGPQLL ELSPGEGFSI
QEKYVAADTL YSKIKEDVKK RALALDEAIS QCTQFHDKID PTLESLKRIV ERLRQPPSIS
AEVEKIKEQI SENKNVSVEL EKLQPVYETL KQRGEEMIAR SEGADKDISA KAVQDKLDQM
VLIWEDIQTL AEEREAKLLD VMELAEKFWC DHMALVATIK DTQDFIRELE GPGVDPSVVK
QQQEAAEAAK EEIDGLQEEL EAVVSLGSEL RAACGEPDKP IVNKSIDELN SAWDALNKTW
KERVDKLGEA MQAAVQYQDG LQALFDWVDI AGSKLASMSP VGTDLETVKQ QTEELKQFKT
EAYQQQIEME RLNHQAELLL KKATQESDKH TVQDPLSELR LLWDSLEDKI ISRQHKLEGA
LLALGQFQHA LDELLAWLTH TEDLLNEQKP VGGDPKAIEI ELAKHHVLQN DVLAHQSTVE
AVKKAGNDLI ESSAVEEASN LRSKLELLNQ RWQNLLEKTE QRKQQLDSAL IQAQGFHGEV
EDLQQWLTDT ERQLLASKPV GGLPETAREQ LNAHMELCAA FEAKEETYKC LMQKGQQMLA
RCPESAETNV EQDINNLKEK WESVQTKLSE RKTKLEEALN LAMEFHNSLQ DFINWLTQAE
QTLTAASRPS LILDTVLFQI DEHKVFATEV NSHRDQIIEL DKTGTHLKYF SQKQDVVLIK
NLLISVQSRW EKVVQRLVER GRALDDARKR AKQFHEAWHK LMEWLEESEK SLDSDLEIAN
DPDKIKMQLA QHKEFQKSLG AKHSVYDTTN RTGRSLKEKT TLADDNLKLD DMLSELRDKW
DTICGKSVER QNKLEEALLF SGQFTDALQA LIDWLYKIEP QLAEDQPVHG DIDLVMNLID
NHKVFQKELG KRTSSVQALK RSARELIEGS RDDSSWVKVQ MQELSTRWET VCALSVSKQT
RLEQALRQAE EFHSVVHVLL EWLAEAEQAL RFHGVLPDDE EALRTLIEQH REFMKKLEEK
KAELNKATGM GEAILAICHP DSITTIKHWI TIIRARFEEV LAWAKQHQQR LAGALAALIA
NQELLEALLS WLQWAETTLT EKDKEVIPQE IEEVKALIAE HQTFMEEMTR KQPDVDKVTK
TYKRKALEPS PVQSHIPVLD KGRAGRKRSP TPGIYPSAAQ AQIETKNPRV NLLLREFANF
DFDIWRKKYM RWMNHKKSRV MDFFRRIDKD QDGKITRQEF IDGILSSKFP TSRLEMSAVA
DIFDRDGDGY IDYYEFVAAL HPNKDAYKPL TDADKIEDEV TRQVAKCKCA KRFQVEQIGD
NKYRVSLLRT SFGDSQQLRL VRILRSTVMV RVGGGWMALD EFLVKNDPCR VHHHGSKMLR
SESNSSITTQ PTIAKGRTNV ELREKFILAD GASQSMAAFR PRGRRSRPSS RGASPNRSTS
LSSQAGQAAA PQAVTTSTPK GTPIQGSKLR LPGYLSGKGF HSGEDSGILS TAATRVRAQF
AETRRTPSRP GSRAGSKAGS RSSSRRGSDA SDFDISEIQS VCSDMSETVP ATSRPTPRAG
SRPGSAKPSK IPTPQRRPLA SKLDKSLKR
//
