ID A0A091F3X1_CORBR Unreviewed; 753 AA.
AC A0A091F3X1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
DE Flags: Fragment;
GN ORFNames=N302_12924 {ECO:0000313|EMBL:KFO63284.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO63284.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO63284.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO63284.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|RuleBase:RU361221}.
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DR EMBL; KK719436; KFO63284.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091F3X1; -.
DR STRING; 85066.A0A091F3X1; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd04591; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd03685; ClC_6_like; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR002249; Cl_channel-7.
DR PANTHER; PTHR11689; CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER; 1.
DR PANTHER; PTHR11689:SF166; H(+)_CL(-) EXCHANGE TRANSPORTER 7; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR PRINTS; PR01118; CLCHANNEL7.
DR SMART; SM00116; CBS; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 81..102
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 181..199
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 242..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 277..299
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 329..353
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 442..461
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 467..489
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 501..525
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 531..552
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 689..747
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO63284.1"
FT NON_TER 753
FT /evidence="ECO:0000313|EMBL:KFO63284.1"
SQ SEQUENCE 753 AA; 83376 MW; 68ED6A6FA239CAA9 CRC64;
QLTPSSFLRI GQLSNVDLNE DIHELETELP RQHPNEIPHN EKLLSLKYES LDYDNSENQL
FLEEERRINH AAFRTVEIKR WVICAMIGIL TGLVACFIDI VVENLAGLKY RVVKDNIDKF
TAKGGLSFSL LLWATLNASV VMVGSVIVAF IEPVAAGSGI PQIKCYLNGV KIPHVVRLKT
LVIKVCGVIL SVVGGLAVGK EGPMIHSGSV IAAGISQGRS TSLKRDFKIF EYFRRDTEKR
DFVSAGAAAG VSAAFGAPVG GVLFSLEEGA SFWNQFLTWR IFFASMISTF TLNSVLSVYH
GNAWDLSSPG LINFGRFDSE KMGYTIQEIP IFIFMGVVGG ILGALFNALN YWLTMFRIRY
IHRPCLQVVE AMLVAAVTAT VGFVMIYCSR DCQPIQGSSV AYPLQLFCAD GEYNSMATAF
FNTPEKSVVN LFHDAPGSYN PMTLGMFTLM YFFLACWTYG LTVSAGVFIP SLLIGAAWGR
LFGISLSYLT KGSIWADPGK YALMGAAAQL GGIVRMTLSL TVIMMEATGN VTYGFPIMLV
LMTAKIVGDY FVEGLYDMHI QLQSVPFLHW EAPVTSHSLT AREVMSTPVT CLRRIERVGT
VVDILSDTSS NHNGFPVVES NADTTQLCGI VPNHLFPPKV FVERANLNLV QRRLKLKDFR
DAYPRFPPIQ SIHVSQDERD CMIDLSEFMN PSPYTVPQEA SLPRVFKLFR ALGLRHLVVV
DNRNEVVGMV TRKDLARYRL GKEGLEELSL AQT
//
