ID A0A091F493_CORBR Unreviewed; 457 AA.
AC A0A091F493;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 28.
DE RecName: Full=Proton-coupled zinc antiporter SLC30A9, mitochondrial {ECO:0000256|ARBA:ARBA00034845};
DE AltName: Full=Solute carrier family 30 member 9 {ECO:0000256|ARBA:ARBA00033405};
DE AltName: Full=Zinc transporter 9 {ECO:0000256|ARBA:ARBA00034922};
DE Flags: Fragment;
GN ORFNames=N302_04065 {ECO:0000313|EMBL:KFO64968.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO64968.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO64968.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO64968.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H(+)(out) + Zn(2+)(in) = 2 H(+)(in) + Zn(2+)(out);
CC Xref=Rhea:RHEA:72627, ChEBI:CHEBI:15378, ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00034428};
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000256|ARBA:ARBA00004240}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion membrane
CC {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004225}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the cation diffusion facilitator (CDF)
CC transporter (TC 2.A.4) family. SLC30A subfamily.
CC {ECO:0000256|ARBA:ARBA00008873}.
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DR EMBL; KK719676; KFO64968.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091F493; -.
DR STRING; 85066.A0A091F493; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR CDD; cd21078; NTD_ZNT9; 1.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR Gene3D; 3.90.530.10; XPA C-terminal domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR040177; SLC30A9.
DR InterPro; IPR037129; XPA_sf.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR13414; HUEL-CATION TRANSPORTER; 1.
DR PANTHER; PTHR13414:SF9; ZINC TRANSPORTER 9; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc transport {ECO:0000256|ARBA:ARBA00022906}.
FT TRANSMEM 128..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO64968.1"
FT NON_TER 457
FT /evidence="ECO:0000313|EMBL:KFO64968.1"
SQ SEQUENCE 457 AA; 51146 MW; 89D8BD448A9C6EAA CRC64;
VKAVLKKREY GPKYTQNNFI TGVRAINEFC LKSSDLDQLR KIKRRSPHDD TETFTVYLRS
DVEAKSLEVW GSPEALARER KRRKEAEIKY RENLFRNQRL LWEYKEFFGN TKPRSSSAAM
FFKGPGKVVM VAICINGLNF FFKLLAWVYT GSASMFSEAI HSLADTCNQA LLALGISQSA
RTPDPSHPYG FTNMRYIASL ISGVGIFMMG AGLSWYHGII GLLHPHPVES LLWAYCILAG
SLVSEGATLL VAINEIRRSA RAKGLSFYQY VVQSRDPSTN VVLLEDAAAV LSVAVAATCM
GLTSLTGNPY YDSVGSLGVG TLLGTVSAFL IYTNTEALLG RSIEPEQLQR LTELLESDPV
VRAIHDVKAT DMGMSKVRFK AEVDFDGRVV TRSYLEKQDI EQLLQEIQQV KTLEELEAFM
LKHGENIIDT LGAEVDRLEK DLKQRNPDVR HVDLEIL
//
