ID A0A091FAP2_CORBR Unreviewed; 167 AA.
AC A0A091FAP2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 30.
DE RecName: Full=Epithelial membrane protein 2 {ECO:0000256|ARBA:ARBA00013552};
GN ORFNames=N302_11689 {ECO:0000313|EMBL:KFO58880.1};
OS Corvus brachyrhynchos (American crow).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae;
OC Corvus.
OX NCBI_TaxID=85066 {ECO:0000313|EMBL:KFO58880.1, ECO:0000313|Proteomes:UP000052976};
RN [1] {ECO:0000313|EMBL:KFO58880.1, ECO:0000313|Proteomes:UP000052976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N302 {ECO:0000313|EMBL:KFO58880.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Apical cell membrane
CC {ECO:0000256|ARBA:ARBA00004221}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm, perinuclear region
CC {ECO:0000256|ARBA:ARBA00004556}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane raft
CC {ECO:0000256|ARBA:ARBA00004285}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363088}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU363088}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the PMP-22/EMP/MP20 family.
CC {ECO:0000256|ARBA:ARBA00006864, ECO:0000256|RuleBase:RU363088}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU363088}.
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DR EMBL; KK718885; KFO58880.1; -; Genomic_DNA.
DR RefSeq; XP_008631604.1; XM_008633382.2.
DR AlphaFoldDB; A0A091FAP2; -.
DR STRING; 85066.A0A091FAP2; -.
DR GeneID; 103615351; -.
DR KEGG; cbrc:103615351; -.
DR CTD; 2013; -.
DR OrthoDB; 5349350at2759; -.
DR Proteomes; UP000052976; Unassembled WGS sequence.
DR GO; GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR003933; EMP-2.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR InterPro; IPR004032; PMP22_EMP_MP20.
DR PANTHER; PTHR10671:SF32; EPITHELIAL MEMBRANE PROTEIN 2; 1.
DR PANTHER; PTHR10671; EPITHELIAL MEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
DR PRINTS; PR01453; EPMEMFAMILY.
DR PRINTS; PR01455; EPMEMPROT2.
DR PROSITE; PS01221; PMP22_1; 1.
DR PROSITE; PS01222; PMP22_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363088};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000052976};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363088};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363088}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..167
FT /note="Epithelial membrane protein 2"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001873240"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363088"
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363088"
FT TRANSMEM 138..163
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363088"
SQ SEQUENCE 167 AA; 18993 MW; 131DC25EB05A0CBA CRC64;
MLILLAFIIV FHITSAALLF ISTIDNAWWV GDNFSTDVWR MCATNTSICM AITDEFNEYQ
SIQAVQAAMI LSTILCCVAF LVFILQLFRL KQGERFVLTS IIQLLSCLCV MIAASIYTDR
HEELHQSRGY GMEVSKGQYG YSFVLAWIAF AFTLISGVMY LVLRKRK
//
