ID A0A091FK09_9AVES Unreviewed; 224 AA.
AC A0A091FK09;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=HLA class II histocompatibility antigen gamma chain {ECO:0000313|EMBL:KFO69953.1};
DE Flags: Fragment;
GN ORFNames=N303_03219 {ECO:0000313|EMBL:KFO69953.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO69953.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO69953.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO69953.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL447122; KFO69953.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091FK09; -.
DR STRING; 55661.A0A091FK09; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035718; F:macrophage migration inhibitory factor binding; IEA:InterPro.
DR GO; GO:0042289; F:MHC class II protein binding; IEA:InterPro.
DR GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0070206; P:protein trimerization; IEA:InterPro.
DR Gene3D; 1.10.870.10; MHC class II-associated invariant chain, trimerisation domain; 1.
DR InterPro; IPR043530; CD74_antigen.
DR InterPro; IPR015386; MHC_II-assoc_invar/CLIP_MHC-bd.
DR InterPro; IPR022339; MHC_II-assoc_invar_chain.
DR InterPro; IPR011988; MHC_II-assoc_invariant_trimer.
DR InterPro; IPR036613; MHCII_invariant_trimer_sf.
DR PANTHER; PTHR14093; HLA CLASS II GAMMA CHAIN; 1.
DR PANTHER; PTHR14093:SF17; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN; 1.
DR Pfam; PF09307; MHC2-interact; 1.
DR Pfam; PF08831; MHCassoc_trimer; 1.
DR PIRSF; PIRSF001992; CD74_antigen; 1.
DR PRINTS; PR01990; CD74ANTIGEN.
DR SUPFAM; SSF48305; Class II MHC-associated invariant chain ectoplasmic trimerization domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..103
FT /note="MHC class II-associated invariant chain/CLIP MHC II-
FT interacting"
FT /evidence="ECO:0000259|Pfam:PF09307"
FT DOMAIN 118..185
FT /note="MHC class II-associated invariant chain
FT trimerisation"
FT /evidence="ECO:0000259|Pfam:PF08831"
FT REGION 181..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 224
FT /evidence="ECO:0000313|EMBL:KFO69953.1"
SQ SEQUENCE 224 AA; 24886 MW; ABF4D41629E2F456 CRC64;
MAEEQRDLIS DHGSNVLNVR DTQRSAWGRK AALSTLSILV ALLIVGQAVT IYFVYHQSGQ
IDKLTKTSQI LQLEALQKKL PASAKPVKKM TMVNSPLAMR VLPFVPSADI MDTAPASNKT
EDQVKHLLLQ TYPRKTFPEL NDNLMGNLKS LKSTLPDADW KALESWLHKW LLFEMAKNPK
PEEDKAVPEK HKVIPAQKDP APALGATVEP EDMIFSGVDV PKLS
//
