ID   A0A091FMS2_9AVES        Unreviewed;       905 AA.
AC   A0A091FMS2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Catenin alpha-1 {ECO:0000313|EMBL:KFO70449.1};
GN   ORFNames=N303_10653 {ECO:0000313|EMBL:KFO70449.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO70449.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO70449.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO70449.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC       {ECO:0000256|ARBA:ARBA00004536}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the vinculin/alpha-catenin family.
CC       {ECO:0000256|ARBA:ARBA00008376}.
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DR   EMBL; KL447174; KFO70449.1; -; Genomic_DNA.
DR   RefSeq; XP_009566514.1; XM_009568219.1.
DR   AlphaFoldDB; A0A091FMS2; -.
DR   STRING; 55661.A0A091FMS2; -.
DR   OrthoDB; 2875365at2759; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0015629; C:actin cytoskeleton; IEA:InterPro.
DR   GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0045296; F:cadherin binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   Gene3D; 6.10.250.2510; -; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 5.
DR   InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR   InterPro; IPR001033; Alpha_catenin.
DR   InterPro; IPR006077; Vinculin/catenin.
DR   InterPro; IPR000633; Vinculin_CS.
DR   PANTHER; PTHR18914; ALPHA CATENIN; 1.
DR   PANTHER; PTHR18914:SF24; CATENIN ALPHA-1; 1.
DR   Pfam; PF01044; Vinculin; 1.
DR   PRINTS; PR00805; ALPHACATENIN.
DR   SUPFAM; SSF47220; alpha-catenin/vinculin-like; 4.
DR   PROSITE; PS00663; VINCULIN_1; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760}.
FT   REGION          864..892
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        864..883
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   905 AA;  100061 MW;  6D15156535BFFE44 CRC64;
     MTAVTAGNVN FKWDPKSLEI RTLAVERLLE PLVTQVTTLV NTSNKGPSNK KRGRSKKAHV
     LAASVEQATE NFLEKGDKIA KESQFLKEEL VAAVEDVRKQ GDLMKSASGE FADDPCSSVK
     RGNMVRAARA LLSAVTRLLI LADMADVYKL LVQLKVVEEG ILKLRNAGTE QDLGIQYKAL
     KPEVDKLNIM AAKRQQELKD VGHRDQMAAA RGILQKNVPI LYTASQACLQ HPDVAAYKAN
     RDLIYKQLQQ AVMGISNAAQ ATASDDAAQQ QGGGGELAYA LNNFDKQIIV DPSTFSEERF
     RPSLEERLES IISGAALMAD SSCTRDDRRE RIVAECNAVR QALQDLLSEY MGNAGRKERS
     DALNSAIDKM TKKTRDLRRQ LRKAVMDHVS DSFLETNVPL LVLIEAAKNG NEKEVKEYAQ
     VFREHANKLI EVANLACSIS NNEEGVKLVR MSASQLEALC PQVINAALAL AAKPQSKLAQ
     ENMDLFKEQW ERQVRVLTDA VDDITSIDDF LAVSENHILE DVNKCVIALQ EKDVDGLDRT
     AGAIRGRAAR VIHVVTSEMD NYEPGVYTEK VLEATKLLSN TVMPRFTEQV EAAVEALSSD
     PAQPMDENEF IDASRLVYDG IRDIRKAVLM IRTPEELDDS DFETEDFDNR SRTSIQTEDD
     QLIAGQSARA IMAQLPQEQK AKIAEQVASF QEEKSKLDAE VSKWDDSGND IIVLAKQMCM
     IMMEMTDFTR GKGPLKNTSD VISAAKKIAE AGSRMDKLGR TIADHCPDSA CKQDLLAYLQ
     RIALYCHQLN ICSKVKAEVQ NLGGELVVSG VDSAMSLIQA AKNLMNAVVQ TVKASYVAST
     KYQKSQGMAS LNLPAVSWKM KAPEKKPLVK REKQDETQTK IKRASQKKHV NPVQALSEFK
     AMESI
//