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Database: UniProt
Entry: A0A091FMX7_9AVES
LinkDB: A0A091FMX7_9AVES
Original site: A0A091FMX7_9AVES 
ID   A0A091FMX7_9AVES        Unreviewed;       613 AA.
AC   A0A091FMX7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   05-JUN-2019, entry version 24.
DE   RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133};
DE            EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133};
DE   Flags: Fragment;
GN   ORFNames=N303_09174 {ECO:0000313|EMBL:KFO70988.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO70988.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO70988.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO70988.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-
CC         bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a
CC         1,2-diacyl-sn-glycerol + H(+); Xref=Rhea:RHEA:33179,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815,
CC         ChEBI:CHEBI:58456, ChEBI:CHEBI:203600; EC=3.1.4.11;
CC         Evidence={ECO:0000256|RuleBase:RU361133};
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DR   EMBL; KL447250; KFO70988.1; -; Genomic_DNA.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.150; -; 1.
DR   Gene3D; 3.20.20.190; -; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR001192; PI-PLC_fam.
DR   InterPro; IPR028398; PLC-epsilon1.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   InterPro; IPR001711; PLipase_C_Pinositol-sp_Y.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR10336; PTHR10336; 1.
DR   PANTHER; PTHR10336:SF6; PTHR10336:SF6; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF00387; PI-PLC-Y; 1.
DR   Pfam; PF00788; RA; 1.
DR   PRINTS; PR00390; PHPHLIPASEC.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00149; PLCYc; 1.
DR   SMART; SM00314; RA; 2.
DR   SUPFAM; SSF51695; SSF51695; 1.
DR   SUPFAM; SSF54236; SSF54236; 2.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50008; PIPLC_Y_DOMAIN; 1.
DR   PROSITE; PS50200; RA; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053760};
KW   Hydrolase {ECO:0000256|RuleBase:RU361133};
KW   Lipid degradation {ECO:0000256|RuleBase:RU361133};
KW   Lipid metabolism {ECO:0000256|RuleBase:RU361133};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW   Transducer {ECO:0000256|SAAS:SAAS01019513}.
FT   DOMAIN       68    158       PI-PLC Y-box. {ECO:0000259|PROSITE:
FT                                PS50008}.
FT   DOMAIN      185    257       C2. {ECO:0000259|PROSITE:PS50004}.
FT   DOMAIN      449    552       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   REGION        1     33       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A091FMX7}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFO70988.1}.
FT   NON_TER     613    613       {ECO:0000313|EMBL:KFO70988.1}.
SQ   SEQUENCE   613 AA;  68887 MW;  A087D45E97A43ADA CRC64;
     SSRGKERKSR KSIFGNNPGR LSPGESATLA KASGKGPFDV MRQTWEDPCS PYNSPASLSA
     IIRTPKCYHI SSLNENAAKR LCRRYSQKLI QHTTCQLLRT YPAATRIDSS NPHPLIFWLH
     GVQLVALNYQ TDDLPLQLNA AMFEANGGCG YVLKPPVLWD KNCSMYQQFC PLERDLDNKE
     PAIYSLTIVS GQNVCPSNST GSPCIEIDVL GMPMDSCHFR TKPIHRNTLN PMWNEQFLFR
     VHFEDLVFLR FAVVENNSSA VTAQRIIPLK ALKRGYRHVQ LHNLHNEALE ISSLFINSRR
     MEENPSGNTL PASKLFSTGE KKAAAIYKVT IHGIPGPEPF TVFNISGGTT AAQLLNQLLA
     STKGTESCAA DYFLMEEKSF ISKEKSECRK APFQRVIGPE EGLVQLLNSW FPEEGYVGRI
     IFKTREENLN ERNILQEAKE DTAISSEDDS FFVQVHDVSP EQPRTVIKAP RFSTAQDVIQ
     QTLCKAKYSY SILSNPNPSD YVLLEEVTKE PANKKSSTPK PSQRILSDQE CVFQAQSKWK
     GAGKFILKLK EQVQAARDDK RKGISFTSEL RKLTKSSKQY RGFISPPLQA LPDNPQSKDE
     RFACSLTFSD IME
//
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