ID A0A091FQ89_9AVES Unreviewed; 631 AA.
AC A0A091FQ89;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Rac GTPase-activating protein 1 {ECO:0000313|EMBL:KFO72685.1};
GN ORFNames=N303_01326 {ECO:0000313|EMBL:KFO72685.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO72685.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO72685.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO72685.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL447381; KFO72685.1; -; Genomic_DNA.
DR RefSeq; XP_009554469.1; XM_009556174.1.
DR AlphaFoldDB; A0A091FQ89; -.
DR STRING; 55661.A0A091FQ89; -.
DR KEGG; cuca:104055092; -.
DR OrthoDB; 22770at2759; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd20821; C1_MgcRacGAP; 1.
DR CDD; cd04382; RhoGAP_MgcRacGAP; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46199; RAC GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR46199:SF1; RAC GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 285..334
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 348..538
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 182..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 30..106
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 249..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 70756 MW; 76ED1FB03094E313 CRC64;
MEATMLSLRR LCDQLMRQVE VLSEGNECQF IQLAKNFEEY RRKLQKAEHE LDRYKDLLMK
AEAERSALDV KLKHARNQVD VEIKRRQKAE MDCEKLERQI QLIRELLMCD ASGSIQLSEE
QKSALAFLNR PRVSVEGPGR KKLSTIDESG SILSDISFDK TDESLDWDSS VVKAVRLKRR
GKRRSSRQFI EGPPGPQKKT RSIGSTVDQG NESIVAKTTL MVPNDGGPIE AISTIQTVPY
SLRSQRKSGP LQAWSSESSI GSKQLESKSE SDVPSTPKNN GGVRLHDFVS KTVIKPESCV
PCGKRVKFGK ISLKCRDCRV VTHPECRERC PLPCIPTLTG TPVRVGEGTL MDFVPSTPPM
IPSIIVHCVN EIEQRGLHET GLYRISGCDK TVRELKEKFL RGKNTPLLSK VDDIHAICSL
LKEFLRSLKE PLLTFRLNKT FMEAAEIPDE DNSVAAMYQA LGELPQANRD TLAFLMVHLQ
RVARSPETKM DVANLAKVFG PTIVAHAVPD PDPMTLLQDT KRQPKVVERL LLLPMDYWSQ
LMMVEQENVD PVHVIENVNA YSAPQTPDFQ VSILGPLTTP EHQLSKMQSS SSLSQRVRST
FSKTTPKFGS KSKSTTLLGH QGRFFASPVL K
//
