ID A0A091FT44_9AVES Unreviewed; 756 AA.
AC A0A091FT44;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 26.
DE SubName: Full=Microprocessor complex subunit DGCR8 {ECO:0000313|EMBL:KFO72319.1};
GN ORFNames=N303_02150 {ECO:0000313|EMBL:KFO72319.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO72319.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO72319.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO72319.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL447300; KFO72319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091FT44; -.
DR STRING; 55661.A0A091FT44; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0070877; C:microprocessor complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0031053; P:primary miRNA processing; IEA:InterPro.
DR CDD; cd19867; DSRM_DGCR8_rpt1; 1.
DR CDD; cd19868; DSRM_DGCR8_rpt2; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.160.590; -; 1.
DR InterPro; IPR040375; DGCR8.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR13482:SF3; MICROPROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR PANTHER; PTHR13482; MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 494..561
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..42
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 84899 MW; 69A7F30F4753F459 CRC64;
MEKYENVPPL PKEPAREMDV ENHACPPPLP PNEQPPPPPL QTSSDAEVMD VGSGGDGQSD
TPAGDTHSIC RTQLLTKGSA CYKSRLIVDP NNSDQSPRTA RHAPSVRKFT PDLKLLKDVK
ISVSFTESCK SKDRKVLYTG VEQDYKADTD FGVNNVNGDL HVCPFGGSNG KAVGVGGEND
DKKDDENDID QEKRVEYAVL DELEDFTDNL MEIDEEGGGF TSKAIVQRDK VDEETLNYSY
EDDFDNDVDA LLEEGLRAPK TRRLENEKYG GESDHQSDGE TSVQPMMTKI KTVLKSRGRP
PTEPLPDGWI MTFQPYFLGT GSIRKHDPPL SSIPCLHYKK MKENEEREQN NDITPNGEVS
PVKHLDKSSE PDCQAEEPDS TAADSGPLDE KDPPGGDAAQ GALGQVKAKV EVCKDESVDL
EDFRCYLEKC FDFEQVTVKK FRTWAERRQF NREMKRKQAE SERPILPANQ KLITLSVQDA
PTKKEFVINP NGKSEVCILH EYMQRVLKVR PVYNFFECEN PSEPFGASVI IDGVTYGAGT
ASSKKLAKNK AARATLEILI PDFVKQTSEE KPKDSEELEY FNHISIEDSR VYELTSKAGL
LSPYQILHEC LKRNHGMGDT SIKFEVIPGK NQKSEYVMTC GKHTVRGWCK NKRVGKQLAS
QKILQLLHPH VKNWGSLLRM YGRESSKMVK QETSDKSVIE LQQYAKKNKP NLHILNKLQE
EMKKLAQERE ETRKKPKMTI VESAQPGSEP LCTVDV
//
