ID A0A091FTN5_9AVES Unreviewed; 1337 AA.
AC A0A091FTN5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Putative ATP-dependent RNA helicase DHX57 {ECO:0000313|EMBL:KFO72993.1};
DE Flags: Fragment;
GN ORFNames=N303_01279 {ECO:0000313|EMBL:KFO72993.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO72993.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO72993.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO72993.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL447392; KFO72993.1; -; Genomic_DNA.
DR STRING; 55661.A0A091FTN5; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17985; DEXHc_DHX57; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR CDD; cd14317; UBA_DHX57; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 2.30.30.1190; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR042615; DHX57_UBA.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF256; ATP-DEPENDENT RNA HELICASE DHX57-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF05773; RWD; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00165; UBA; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFO72993.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFO72993.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 121..165
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 246..273
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 505..672
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 780..960
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT ZN_FING 246..273
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 23..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..441
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO72993.1"
FT NON_TER 1337
FT /evidence="ECO:0000313|EMBL:KFO72993.1"
SQ SEQUENCE 1337 AA; 151334 MW; 959D95729A15C1F8 CRC64;
GGNRKCSTKI WDDGDDFCLF EEPRLESRSN ASARRGGQTK QKAEARMPLQ TIHMTSENQR
RVKELLQELQ GQELAPESEV AGSGEDNDET DYLDDEQCWS TDQEVSDIIP KLPADLPVHR
IVESEVSSFA VHKLSRYGFD SELCRTVLRS CNGNIGASLE YLLLKCFTER YGEKIQISTT
AVEASQKECL EQRQEEAFAL QSIYGEKFVE RIQNRVWTFT LEMEYLANRL SKSKQKGDCT
TNTAKQTSKE ICKFYLQGGC RFGSKCRFRH ELPPSHPLKP AKNSVDDAHL RLDNDGPVYE
LEVRFPEENK YPLQAPLVAF YSTNENLPLA CRLHIAEFLF GKALIAAESN EPVVYTLVTS
LEDESEISEL LKNTHHKYSV PPVSLLATPS VKLQTEMLMK SYSLVTRTPS IHSLSQAPIV
SRPQEEEEVA EEEEDEPEEA VAENESYVKL KKKLSEKYDV PAKSLYNENV KICMQFRLKK
SSRHFRSMLY ERQKLPAWQE RETILDLLKS HQVLVVSGMT GCGKTTQIPQ FILDESLQGS
PSRVANIICT QPRRISAISV AERVAKERTE RIGLTVGYQI RLESVKSSAT RLLYCTTGVL
LRRLEGDLTL QGVTHVIVDE VHERTEESDF LLLVLKDIMV QRPDLRIILM SATLNADLFS
QYFHSCPIIN IPGRTFPVDQ FFLEDVLAMT RYVLEDSSPY RRKTKQENKQ NGRQKRTAFE
EVEEDLRRAG VLEGTDTVVR DSDPDQKLSL KQLLSRYKGV NKTVLKTMSV MDLDKVNLEL
IEALLEWIVA GRHSYPPGAV LIFLPGLAEI KMLYEQLQSN ALFNNRHSER CVVYPLHSSL
SSEEQQSVFL RPPTGVIKII ISTNIAETSV TIDDVVYVID SGKMKEKRYD PSKGMESLED
TFVSKANALQ RKGRAGRVAS GVCFHLFSSH HYNHLLIRQQ LPEIQRVPLE QLCLRIKILE
MFSAQSLHSV LSQLIEPPRT ESLRASKVRL QDLGALTPDE KLTPLGYHLA SLPVDVRIGK
LMLFGTIFRC LDPALTIAAS LAFKSPFVSP WDKREEANKK KLEFAVGNSD YLALLQAYKG
WCLSIKEGSQ ASYNYCRENF LSGRVLQEIA SLKRQFTELL SDIGFVKEGL RARDIEKKWS
QGGDGVLDAT GEEANSNAEN IKLISAMLCA ALYPNVVQVK KPEGKYQKTS TGAVKMQPKA
EELKFVTKND GYVHIHPSSV NYQTKHFESP YLVYHEKIKT SRVFIRDCSM VSVYPLVLLG
GGQVHMHLQK GEFVISLDDG WIRFVAASHQ VAELVKNLRC ELDQLLQDKI KNPGMDLCVC
PRGSQIISMI VKLVTTQ
//
