ID   A0A091FVU7_9AVES        Unreviewed;       406 AA.
AC   A0A091FVU7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 21.
DE   SubName: Full=Aminopeptidase N {ECO:0000313|EMBL:KFO73773.1};
DE   Flags: Fragment;
GN   ORFNames=N303_08283 {ECO:0000313|EMBL:KFO73773.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO73773.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO73773.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO73773.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M1 family.
CC       {ECO:0000256|ARBA:ARBA00010136}.
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DR   EMBL; KL447470; KFO73773.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091FVU7; -.
DR   STRING; 55661.A0A091FVU7; -.
DR   MEROPS; M01.016; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 1.25.50.20; -; 1.
DR   Gene3D; 2.60.40.1910; -; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR024571; ERAP1-like_C_dom.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR11533:SF172; AMINOPEPTIDASE N; 1.
DR   PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR   Pfam; PF11838; ERAP1_C; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000313|EMBL:KFO73773.1};
KW   Hydrolase {ECO:0000313|EMBL:KFO73773.1};
KW   Protease {ECO:0000313|EMBL:KFO73773.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760}.
FT   DOMAIN          2..98
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
FT   DOMAIN          189..406
FT                   /note="ERAP1-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11838"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO73773.1"
FT   NON_TER         406
FT                   /evidence="ECO:0000313|EMBL:KFO73773.1"
SQ   SEQUENCE   406 AA;  46658 MW;  CB7966F87481246C CRC64;
     TDALATSHPL SFPEDEINTP AQISEVFDSI AYSKGASVLR MLSDFLTDDV FKKGLQSYLH
     NFSYSNTVYT DLWLHLQEAA RENNIVLPYN VSHIMDRWTL QMGFPVVTVN TLTGTVNQSH
     FLLDPNSVVE RPSAFNYIWI VPITWMTPQG SGDRYWLTQV SGMAHHAQAW GSRCHLLAAV
     EIRVPRRCSG YFRVNYNQEN WNHLLNQLST NHQVIPVINR AQIIDDAFNL ARAKYINVTL
     ALRTTRFLSN ETEYMPWEAA LNNLHYFQLM FDRSEVFGVM TKYIQKQVTP LFNYYKNITN
     NWVSIPSGLM DQYNEINAIS TACSYGITEC RDLATSYFSH QWQANVTNNP IPPNLRSSIY
     CSIVATGGEE AWNFIWERFR EATVVSESDK LRTALSCSTQ PWILKR
//