ID A0A091G7E9_9AVES Unreviewed; 1784 AA.
AC A0A091G7E9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Signal-induced proliferation-associated 1-like 1 {ECO:0000313|EMBL:KFO70132.1};
GN ORFNames=N303_05375 {ECO:0000313|EMBL:KFO70132.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO70132.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO70132.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO70132.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL447129; KFO70132.1; -; Genomic_DNA.
DR RefSeq; XP_009562008.1; XM_009563713.1.
DR STRING; 55661.A0A091G7E9; -.
DR OrthoDB; 25782at2759; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 6.10.140.210; -; 1.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR021818; SIPA1L_C.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF10; SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF21022; Rap-GAP_dimer; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR Pfam; PF11881; SPAR_C; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760}.
FT DOMAIN 599..816
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT DOMAIN 954..1018
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 44..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1069..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1147..1214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1251..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1311..1343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1362..1457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1486..1557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1625..1646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1721..1769
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1069..1096
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1147..1170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1186..1214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1253..1283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1311..1333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1376..1457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1486..1531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1532..1557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1784 AA; 197522 MW; 8C355FDBF02D8E3A CRC64;
MTSLKRSQTE RAVATGVSVG TDGTSKVHSD DFYMRRFRSQ NGSLGSAVMA PVGPPRNESS
HHVTSTPGVP KMGVRARIAD WPPRKENIKE TSRSSQDIET SSCLDSMSSK SSPGSQGSSV
NLNAGDSVML KSIQSTLKTK TRQSENLDSR FLTPDGYPSS PRKALRRIRQ RSNSDITISE
LDVDSFDECI SPTFKSGPSL HREYGSTSSI DKQGTSGESF FDLLKGYKDE KSDQRSQATT
KLSELLIASG SKGSGFSLDV IDGPITQREN LRLFKEREKP LKRRSKSETG DSSIFRKLRN
AKGEGELGKS SDLEDNRSED SIKPWTCPKC FAHYDVQSIL FDLNEAAINR HNVIKRRNTT
TGASAAAVAS LVSGPLSHSA SFNSPMGSTE DLNSKGSLNM DQGDDKSNEL VMSCPYFRNE
IGGEGERKIS LSKCNSGSFS GCESTSFEST LSSHCTNAGV AVLEVPKENH MLHLDRVKRY
IVEHVDLGAY YYRKFFYQKE HWNYFGADEN LGPVAVSIRR EKPEEIKENG PQYNYRIIFR
TSELMTLRGS VLEDAIPSTA KHCTARGLPL KEVLEYVVPE LNIHCLRLAF NTPKVTEQLM
KLDEQGLSYQ LKVGIMYCKA GQSTEEEMYN NESAGPAFEE FLQLLGERVR LKGFEKYRAQ
LDTKTDSTGT HSLYTTYKDY EIMFHVSTML PYTPNNKQQL LRKRHIGNDI VTIVFQEPGA
QPFSPKNIRS HFQHVFVIVR VHGPCTDSVC YSVAVTRSRD VPSFGPPIPK GVTFPKSNVF
RDFLLAKVIN AENAAHKSEK FRAMATRTRQ EYLKDLAEKN VTNTPIDPSG KFPFISLASK
KKEKSKPYPG AEIYSSGAIV WSVHAKDYSK GMEIDCLLGI SNEFVVLIEQ DTKSVVFNCS
CRDVIGWTST DTNIKIFYER GECVSLESFI SNIDDIKEIV KRLELVTKGC ETVEMTLRRN
GLGQLGFHVN YEGIVADVEP YGYAWQAGLR QGSRLVEICK VAVATLTHEQ MIDLLRTSVT
VKVVIVPPYE DCTPRRSSSE NYRMPVMEYK VNEGMSYEFK FPFRNNNKWQ RNASKGQGPH
VAQVPSQIQS PVTSRIGSGK EGKMPPPERA ANIPRSISSD GRPLESRRLS PGSDVYVTVS
SIALARSQQC RNSPSNLSSS SETGSGGGTY RQKSMPEGFG ISRRSPASID RQNTQSDTGG
SGKSTPSWQR SEDSIADQME PTCHLPAVSK VLPTFRESPS GRLMRQDPVV HLSPNKQGHS
DSHYSSHSSS NTLSSNASSA HSDEKWYDSG ERTESEMNSY NYLQGTSADS GIDTTSYGPS
HGSTASLGAA TSPRTGLTKE KVAPLWHSSS EVVSIADRTL EKESHMDRKT ESSLSLDIHS
KSQPASNPLT RENSAYSLSD AVSHTSTMSS RHSASPVVLT SARSSPKEEL HSATSPQLAP
SFSSSSSSAS GPRTFYPRQG ATSKYLIGWK KPEGTINSVG FMDSRKRHQS DGNEMAHPRL
RASARDLRAS PKRASKSTVE EELKKLIDLD SPTPESQKNF KSHTLSCQSP FPSTPTTRRA
LQRTLSDESI YSGQRDHFFT SRASLLDQAM PNDVLFTSTY PSLPKSLPLR RPSYTLGMKS
LHGEFSASDS SLTDLQEQRR QPMPDPGLMP LPDSASDLDW SNLVDAAKAF EVQRASFFAA
ADENHRPVSA ASSGDQAEDQ LTAQIKPYTG KESPPTLASK VDQLEGLLKM LQEDLRKEKE
DKASLQAEVQ HLREDNLRLQ EESQNATEKL KKFTEWVFNT IDMS
//
