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Database: UniProt
Entry: A0A091GCQ8_9AVES
LinkDB: A0A091GCQ8_9AVES
Original site: A0A091GCQ8_9AVES 
ID   A0A091GCQ8_9AVES        Unreviewed;        74 AA.
AC   A0A091GCQ8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Vesicle-associated membrane protein 8 {ECO:0000256|ARBA:ARBA00039271};
DE   AltName: Full=Endobrevin {ECO:0000256|ARBA:ARBA00042205};
DE   Flags: Fragment;
GN   ORFNames=N303_01045 {ECO:0000313|EMBL:KFO80165.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO80165.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO80165.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO80165.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004521};
CC       Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004521}.
CC       Early endosome membrane {ECO:0000256|ARBA:ARBA00037832}; Single-pass
CC       type IV membrane protein {ECO:0000256|ARBA:ARBA00037832}. Endosome
CC       membrane {ECO:0000256|ARBA:ARBA00037867}; Single-pass type IV membrane
CC       protein {ECO:0000256|ARBA:ARBA00037867}. Late endosome membrane
CC       {ECO:0000256|ARBA:ARBA00037845}; Single-pass type IV membrane protein
CC       {ECO:0000256|ARBA:ARBA00037845}. Lysosome membrane
CC       {ECO:0000256|ARBA:ARBA00037863}; Single-pass type IV membrane protein
CC       {ECO:0000256|ARBA:ARBA00037863}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC       {ECO:0000256|ARBA:ARBA00004211}. Zymogen granule membrane
CC       {ECO:0000256|ARBA:ARBA00037825}; Single-pass type IV membrane protein
CC       {ECO:0000256|ARBA:ARBA00037825}.
CC   -!- SIMILARITY: Belongs to the synaptobrevin family.
CC       {ECO:0000256|ARBA:ARBA00008025}.
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DR   EMBL; KL448090; KFO80165.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091GCQ8; -.
DR   STRING; 55661.A0A091GCQ8; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042589; C:zymogen granule membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.20.5.110; -; 1.
DR   InterPro; IPR001388; Synaptobrevin-like.
DR   InterPro; IPR016444; Synaptobrevin/VAMP.
DR   InterPro; IPR042855; V_SNARE_CC.
DR   PANTHER; PTHR45701; SYNAPTOBREVIN FAMILY MEMBER; 1.
DR   PANTHER; PTHR45701:SF7; VESICLE-ASSOCIATED MEMBRANE PROTEIN 8; 1.
DR   Pfam; PF00957; Synaptobrevin; 1.
DR   PRINTS; PR00219; SYNAPTOBREVN.
DR   SUPFAM; SSF58038; SNARE fusion complex; 1.
DR   PROSITE; PS50892; V_SNARE; 1.
PE   3: Inferred from homology;
KW   Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW   ProRule:PRU00290}; Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        53..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..49
FT                   /note="V-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000259|PROSITE:PS50892"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO80165.1"
FT   NON_TER         74
FT                   /evidence="ECO:0000313|EMBL:KFO80165.1"
SQ   SEQUENCE   74 AA;  8435 MW;  B3E861114B2E6BBD CRC64;
     KSIMTRNVER ILARGENLEQ LHSKSQDLEA TSEHFKTTSQ KVARRHWWKN VKLLFILGVV
     GAIILILIIL LATG
//
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