ID A0A091GGW9_9AVES Unreviewed; 1109 AA.
AC A0A091GGW9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Sushi, nidogen and EGF-like domain-containing protein 1 {ECO:0000313|EMBL:KFO81208.1};
DE Flags: Fragment;
GN ORFNames=N303_11050 {ECO:0000313|EMBL:KFO81208.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO81208.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO81208.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO81208.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL448192; KFO81208.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091GGW9; -.
DR STRING; 55661.A0A091GGW9; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR CDD; cd00054; EGF_CA; 9.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.10.25.10; Laminin; 12.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003886; NIDO_dom.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF30; DELTA-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 10.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF06119; NIDO; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR PRINTS; PR01983; NOTCH.
DR SMART; SM00032; CCP; 1.
DR SMART; SM00181; EGF; 13.
DR SMART; SM00179; EGF_CA; 11.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00539; NIDO; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 8.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS00022; EGF_1; 12.
DR PROSITE; PS01186; EGF_2; 11.
DR PROSITE; PS50026; EGF_3; 12.
DR PROSITE; PS01187; EGF_CA; 3.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS51220; NIDO; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 34..189
FT /note="NIDO"
FT /evidence="ECO:0000259|PROSITE:PS51220"
FT DOMAIN 199..240
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 242..278
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 280..316
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 318..354
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 360..396
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 399..431
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 472..508
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 546..582
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 598..655
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 655..691
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 693..729
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 731..767
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 769..805
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 810..908
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 909..1007
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1008..1100
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DISULFID 230..239
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 268..277
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 306..315
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 344..353
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 386..395
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 421..430
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 498..507
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 572..581
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 626..653
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 681..690
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 719..728
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 757..766
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 795..804
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO81208.1"
FT NON_TER 1109
FT /evidence="ECO:0000313|EMBL:KFO81208.1"
SQ SEQUENCE 1109 AA; 120722 MW; E1EBE5490292DFC2 CRC64;
LQVNNNGIIS FLKEVSQFTP VAFPISKDRR VVAAFWADVD NRRAGDVYYR ESTEQPILER
ASRDIVQYFP EFPEFSAQWV FIATWYRVTF FGGNSFSPVN TFQIVLITDG KLSFTIFNYE
SITWTTGMHA SSGGDFAGLG GIAAQAGFNA GDGKRYFNIP GSRTDDIADV EMTTNVGIPG
RWVFRIDDAQ VQVGGCSNTT SVCLTLRPCL NGGKCIEDCI TGNPSYTCSC LAGFTGKRCH
IDVDECLSHP CLNGATCLNG AGNFSCRCPT GFRGANCETE ESPCESKVCQ NSGRCQVVNG
TATCSCQLGY TGADCQTEVN ECESSPCLNG GHCVDLLNNY TCVCLEPFVG QRCETGGPRV
PSACLSQPCQ NAGSCVDTEQ GYVCECPEGY TGQDCRDKFW EGCECRNGGS CLEGNMTVCQ
CPPGFFGLVC EFEVTTTPCN MNTQCPDGGY CMEYGGSYLC VCHTDYGTNH TMPSPCDSEP
CLNGGSCEVH DDSYTCECPR GFLGKHCEKV RVSVGRWREA EALGGPGAAG GSCPYRFTGK
HCEIGKPDPC ASGPCQNGGT CFHYIGKYKC DCPLGYAGRH CEIGRCTTPP TPHLSPEVDC
GVPSEVKHAQ VSFNSTKVGS LAEYQCELGY TLSPHNHPRV CRLPGVWTDP PECDEIDECR
SQPCLNGGHC KDRIAEFLCL CEPGYTGAQC ESDVDECHSE PCKNGGTCRD LPGTFTCHCP
EGFVGTQCET EVNACESSPC RNGGECESYR GSYLCVCPEG FFGYHCETAS DPCFSSPCGS
RGYCLSSNGT HSCTCKVSYT GKSCEKELLP PTSLKVERVE DTGVLISWHP PEDAAARQLI
DGYAVTYVSL DGSYRRTDFV DRSRSAHQLR ALASGRAYNI SVFSVKRNVN NKNDISRPVM
LTTRTRPRPV EGFEITNVTA SAITVQWALH RLKHSTVSRV RVSIRQLGDL ADRTVELNSS
VAKYTFLDLQ PGERYIVHVT TLSGLGTEDH PSESLATAPF HVWTRPLPPQ NLTASRVTAT
SVSMAWEQPP AGAVEGYIIN VTTTQSVKSR YVPNGKLMSY TVRDLLPGQQ YRLSVTAVQN
TEQGQVHSEP VHLYVTTREC RDGTQGRRW
//
