ID A0A091GIM8_9AVES Unreviewed; 734 AA.
AC A0A091GIM8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Cyclic nucleotide-gated channel cone photoreceptor subunit alpha {ECO:0000313|EMBL:KFO74002.1};
DE Flags: Fragment;
GN ORFNames=N303_07514 {ECO:0000313|EMBL:KFO74002.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO74002.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO74002.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO74002.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL447476; KFO74002.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091GIM8; -.
DR STRING; 55661.A0A091GIM8; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.5.300; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR032406; CLZ_dom.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638:SF6; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3; 1.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF16526; CLZ; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KFO74002.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 348..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 524..638
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 147..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 665..710
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 148..191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 734
FT /evidence="ECO:0000313|EMBL:KFO74002.1"
SQ SEQUENCE 734 AA; 84925 MW; 76254F0303846CE8 CRC64;
MAKINTQHSY PGMHSLSVRT TDEDIERIGN GYIRTHSLCE DASSELQRVI SVDGRHLSES
QTSSFTGRGA MARLSRFVIS VRSWATRHSH HEDQRPDSFL ERIRGPELIE VSSRQSNIRS
FLGIREQPGG IKSRWPLARF NVNYSNNTNE DKKEEKKEVK EEKKEEKKEE KKEEKKEEKK
DDKKDDKKDD KKKEEKKKEI YVIDPSSNIY YNWLTIIAAP VFYNWCMLVC RACFDELQVD
HIKLWLFLDY GSDIIYVFDM FVRFRTGFLE QGLLVHDEKK LRDHYTKTVQ FKLDVLSLVP
TDLAYLKLGL NYPELRFNRL LRISRLFEFF DRTETRTNYP NMFRIGNLVL YILIIIHWNA
CIYFAISKLI GFGTDSWVYP NVSIPEYGRL SRKYIYSLYW STLTLTTIGE TPPPVKDEEY
LFVVIDFLVG VLIFATIVGN VGSMISNMNA SRAEFQAKVD SIKQYMHFRK VTKDLEARVI
KWFDYLWTNK KTVDEKEVLK NLPDKLKAEI AINVHLDTLK KVRIFQDCEA GLLIELVLKL
KPTVFSPGDY ICKKGDIGRE MYIIKEGKLA VVADDGITQF VVLSDGSYFG EISILNIKGS
KSGNRRTANI RSIGYSDLFC LSKDDLMEAL TEYPEAKKAL EEKGRQILMK DNLIDEEAAK
AGADPKDLEE KVERLETALD TLQTRFARLL AEYTASQQKV KQRLAKVETR VKKYGSGTLS
VGEAEAEKTE EEKK
//
