ID A0A091GJF4_9AVES Unreviewed; 479 AA.
AC A0A091GJF4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Noelin {ECO:0000313|EMBL:KFO82525.1};
DE Flags: Fragment;
GN ORFNames=N303_06190 {ECO:0000313|EMBL:KFO82525.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO82525.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO82525.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO82525.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
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DR EMBL; KL448313; KFO82525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091GJF4; -.
DR STRING; 55661.A0A091GJF4; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR GO; GO:0003190; P:atrioventricular valve formation; ISS:AgBase.
DR GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; ISS:AgBase.
DR GO; GO:0010629; P:negative regulation of gene expression; ISS:AgBase.
DR GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:AgBase.
DR GO; GO:0010628; P:positive regulation of gene expression; ISS:AgBase.
DR InterPro; IPR022082; Noelin_dom.
DR InterPro; IPR003112; Olfac-like_dom.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR PANTHER; PTHR23192:SF34; NOELIN; 1.
DR PANTHER; PTHR23192; OLFACTOMEDIN-RELATED; 1.
DR Pfam; PF12308; Noelin-1; 1.
DR Pfam; PF02191; OLF; 1.
DR SMART; SM00284; OLF; 1.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS51132; OLF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00446}; Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..479
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001873977"
FT DOMAIN 221..473
FT /note="Olfactomedin-like"
FT /evidence="ECO:0000259|PROSITE:PS51132"
FT COILED 89..137
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 173..219
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 222..404
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00446"
FT NON_TER 479
FT /evidence="ECO:0000313|EMBL:KFO82525.1"
SQ SEQUENCE 479 AA; 54907 MW; 59E07CE8EAEEC8BB CRC64;
MSVPLLKIGV VLSTMAMITN WMSQTLPSLV GLNTTKLTAA TGGTLDRSTG VKESWQVYSS
AQDSEGRCIC TVVAPQQTMC SRDARTKQLR QLLEKVQNMS QSIEVLDRRT QRDLQYVEKM
ENQMRGLESK FKQVEESHKQ HLARQFKAIK AKMEELRPLI PVLEEYKADA KLVLQFKEEV
QNLTSVLNEL QEEIGAYDYE ELQNRVSNLE ERLRACMQKL ACGKLTGISD PITIKTSGSR
FGSWMTDPLA PEGENKVWYM DSYHNNRFVR EYKSMADFMN TDNFTSHRLP HPWSGTGQVV
YNGSIYFNKY QSHIIIRFDL KTETILKTRS LDYAGYNNMY HYAWGGHSDI DLMVDENGLW
AVYATNQNAG NIVISKLDPN TLQSLQTWNT SYPKRSAGEA FIICGTLYVT NGYSGGTKVH
YAYQTNASTY EYIDIPFQNK YSHISMLDYN PKDRALYAWN NGHQILYNVT LFHVIRSDE
//
