ID   A0A091GK83_9AVES        Unreviewed;       685 AA.
AC   A0A091GK83;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Myeloperoxidase {ECO:0000313|EMBL:KFO74537.1};
DE   Flags: Fragment;
GN   ORFNames=N303_13047 {ECO:0000313|EMBL:KFO74537.1};
OS   Cuculus canorus (common cuckoo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX   NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO74537.1, ECO:0000313|Proteomes:UP000053760};
RN   [1] {ECO:0000313|EMBL:KFO74537.1, ECO:0000313|Proteomes:UP000053760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO74537.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL447524; KFO74537.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091GK83; -.
DR   STRING; 55661.A0A091GK83; -.
DR   Proteomes; UP000053760; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   CDD; cd09824; myeloperoxidase_like; 1.
DR   Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR   InterPro; IPR019791; Haem_peroxidase_animal.
DR   InterPro; IPR010255; Haem_peroxidase_sf.
DR   InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR   PANTHER; PTHR11475:SF63; EOSINOPHIL PEROXIDASE; 1.
DR   PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR   Pfam; PF03098; An_peroxidase; 1.
DR   PRINTS; PR00457; ANPEROXIDASE.
DR   SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR   PROSITE; PS50292; PEROXIDASE_3; 1.
PE   4: Predicted;
KW   Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Peroxidase {ECO:0000313|EMBL:KFO74537.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053760}.
FT   BINDING         446
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO74537.1"
FT   NON_TER         685
FT                   /evidence="ECO:0000313|EMBL:KFO74537.1"
SQ   SEQUENCE   685 AA;  77795 MW;  3F05839E7D12DA43 CRC64;
     LAEELSDVSI LSSVDKAKLL VDAAYKRTRD RIKEHLQNDA LTPVELLGYF KQPVAGTRTA
     SRAADYMETT LLKEKLHRAV RGDFNVTDLL TPVQLERIFK ASGCDQQEKK MTCDASGQYR
     TITGECNNRK HPSLGASNRA LVRWLPADYE DGVSIPHGWT EGKHFFGFPF PLVRKVSNEI
     VRFSPEQLRL DQQRSLMFMQ WGQFIDHDLD FSPDTPSRVT FSGKVDCETS CDKEPPCFPI
     KIPPNDPRIK NTKDCLPFSR SAAVCPSGRA TREQINALTS FLDGSMVYGS EVPLANKLRN
     QTNQLGLLAV NHNFTDQGRE YMPFAGTAKD PCLIVSKGAK IPCFLAGDFR ANEMLGLTCM
     HTLFVREHNR LARQLKRLNP HWGGEKLYQE ARKILGAMIQ IITYRDYLPL LLGRSFQKLI
     PLYRGYNESV DPRISNVFTL AFRFAHASVP PTVDRLNENY KPIGPKIPLR NAFFAVWRIV
     KEGGIDPFFR NLIVSQAKLM TQKQMVVDDL RDHMFEQVER IGFDLPALNM QRGRDHGLAG
     YSSWRKFCGL SQPSGLNSLA QVLRNVDLAK KFLQLYGTPK NIDIWIGALA EPFVKGGRVG
     PLMACLIGAQ FRNVRDGDRF WWQNSGVFTP QQRSSLAKIS LSRIICDNTN ISKVPKRIFL
     ANRNPWFFVS CRRFPKLDLR AWKSK
//