ID A0A091GKK9_9AVES Unreviewed; 2260 AA.
AC A0A091GKK9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};
DE Flags: Fragment;
GN ORFNames=N303_06198 {ECO:0000313|EMBL:KFO82533.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO82533.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO82533.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO82533.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in the organization of the endoplasmic reticulum
CC exit sites (ERES), also known as transitional endoplasmic reticulum
CC (tER). Required for secretory cargo traffic from the endoplasmic
CC reticulum to the Golgi apparatus. {ECO:0000256|RuleBase:RU364101}.
CC -!- SUBUNIT: SEC16A and SEC16B are each present in multiple copies in a
CC heteromeric complex. {ECO:0000256|RuleBase:RU364101}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}. Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU364101}.
CC -!- SIMILARITY: Belongs to the SEC16 family.
CC {ECO:0000256|ARBA:ARBA00005927, ECO:0000256|RuleBase:RU364101}.
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DR EMBL; KL448313; KFO82533.1; -; Genomic_DNA.
DR STRING; 55661.A0A091GKK9; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:UniProt.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09233; ACE1-Sec16-like; 1.
DR Gene3D; 1.25.40.1030; -; 1.
DR InterPro; IPR024298; ACE1_Sec16_Sec31.
DR InterPro; IPR024880; Sec16.
DR InterPro; IPR024340; Sec16_CCD.
DR PANTHER; PTHR13402:SF13; PROTEIN TRANSPORT PROTEIN SEC16A; 1.
DR PANTHER; PTHR13402; RGPR-RELATED; 1.
DR Pfam; PF12932; Sec16; 1.
DR Pfam; PF12931; Sec16_C; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|RuleBase:RU364101};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892,
KW ECO:0000256|RuleBase:RU364101};
KW Golgi apparatus {ECO:0000256|RuleBase:RU364101};
KW Membrane {ECO:0000256|RuleBase:RU364101};
KW Protein transport {ECO:0000256|RuleBase:RU364101};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Transport {ECO:0000256|RuleBase:RU364101}.
FT DOMAIN 1339..1436
FT /note="Sec16 central conserved"
FT /evidence="ECO:0000259|Pfam:PF12932"
FT DOMAIN 1508..1742
FT /note="Ancestral coatomer element 1 Sec16/Sec31"
FT /evidence="ECO:0000259|Pfam:PF12931"
FT REGION 1..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 867..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 910..1067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1097..1127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1211..1264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1881..1943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1957..2088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2100..2119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2139..2203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..628
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 913..1026
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1050..1064
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1211..1244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1246..1264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1914..1943
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1960..1983
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1994..2008
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2022..2055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2056..2080
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2152..2166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2185..2203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO82533.1"
FT NON_TER 2260
FT /evidence="ECO:0000313|EMBL:KFO82533.1"
SQ SEQUENCE 2260 AA; 245560 MW; 769DA2F933DBEE64 CRC64;
QTPQSSSLDN PPKGNALVMQ SSSPAAFPQP AVQPVSQWKP VQGNLQSPVR NFVPYPEPSS
QIDVHNISQS SVSASHPPPQ TNVQQSSVHQ GIPQNIIQAP LPVGCEKNGK NSSPNSSHHM
NSIQPGNVFR QNTELTNAWL NQPYQEQFYP QPPLQGSSFI IPTAQGNNPQ TQSPGMSETS
NRPVPTERDS GTLSMFFKGD EAENEEILSS EKNCVVEKTE FDACQPNSAS LYHPPMHLQR
VASNVLSQTQ TGPGLASEMV QRGVDVHDDK ACIGGTSGNG GSQYENVENL ECIQNQEVLP
SEPQNIDASS PAAGPDLYRY GSFPGHMLPK NAVVSHAEGG PNLEAPDSLP HPVRPDSVSS
NYSNISHRSA SGSARPPEQV GTFIQQESGK PDEESSASFF KQIDSSPLGG DLSELNLSKN
YHGNLSQPPT PSPPKPTGVF QTSANSSFEP VRSHGVGIKP AEIDQAKMVV ELQENHSNQK
NIKKNAAAPA ASPGNLEQPP DNLETIFMPQ VHPLPLAVAG EVGNMLHSGP ITESIQSVSE
RRSSTRAQGA VKKCDSPATT LWAHNELPNF GGNVLLAPAA PAVYVPAKQT VEIIQPPEEG
LSIQQPSKPG AIVGQLSQDG NISSENLENP PKMGEEEALQ SQASSGYASL LSSPPTESLQ
NQPILIAQPN QSYNLAQPIN FSISLSNQLS SNENNQPVKD TGIGDKLAMG PQTSHAGGII
SGENVPLPAM QVGSLLVNAL PNTNLVKHNL LQSPVNSSDT ASNQPANLLM KTPLNLAPEG
QKNIDLEGFV PEFASKVGSN SSISPGMSLP SGSAGEMVPP VNSVAQGNNP AHHSNSKEEI
TGVLDFTVSR TLEKSSANNS VLVHNQSLPG GPVYPHQSAG GAGQVGPEVR DNEHFYQQVI
KDVQHQAVSD RAVQGALPSQ PQMQAAQMQQ PAPSGQSSVP SNYQIAAGTK AMQASQQREN
QVLSNHPQPV GPPEASSAQL TRYDQTSPDK QPVSGQPSGA PSSTAPSTTT QSAVSNVQQD
LQRPPVPQTP QDAFGPPQNP YYYYRHPYDA YQPPYPPPYP PTDPRTGAHL YYMDDSYGQY
DPRYRHYDST SAAYMEPGSY RYPEPERPSS RASHCSERPS SRQGYPEDYY TKSGWSDYYP
GYYPNSYDYG DPSHWERYSS AYDPRYRDPR SYDRRYWYDA EHNPYQKRDA YSYGNRHDRY
EDNWRYDPRF TGSFDDESEP HRDPYGDEFD RRSVHSEHSG HSLRSSRSIH SHQSSFSSRS
QQSQLYRSNH DLTANVYETT VQAVSLHTDY PYGGYAANFD GQQPFTDYGY PAEAGWAAVE
QAPLRPSTPE KFSVPHICAR FGPGGFLIKV LPNLPSEGQP ALVEIHSMEA MLQHSPEQEE
MRAFPGPLDK DDTHKVDVIN FAQNKATQCF KNENLIDKES ASLLWDFIVL LCRQNGTVVG
TDLAELLLRD HKTVWLPGKS PNEANLIDFT NEAVEQVEEE SGEAQLSFLT DGLITTIDSL
EKETERFREL LLYGRKKDAL ESAMKHGLWG HALLLASKMD SRTHARVMTR FANSLPINDP
LQTVYQLMSG RMPAASTCCG DEKWGDWRPH LAMVLSNLTN NVDLESRTIA TMGDTLASKG
LLDAAHFCYL MAQVGFGVYT RKTTKLVLIG SNHSLPFLKF ATNEAIQRTE AYEYAQSLGT
QPGCLPNFQV FKFIYACRLA EMGLAAQAFH YCEVISRTVL KDPHYYSPVL IGQLIQMSSQ
LRLFDPQIKE KPDQESFIEP SWLVRLRHVD GQIKEGAIAY NTDRSTPPPY ACSTPSSELD
HGSQCDGAGV GRDMGPGAEN PLLASLLPNV AQQMQTVQLM PSVPQAALDG SAAMIPPGDQ
EAVRSVPFYS VASQPVGPGP GFAPPGFSNP YGTEPTPMYL GSALSPGGPP QETEPRSEEQ
TNLETGMQRI APESPSQNSF PDQREEDFYG RMASMGYGRR SRTASESSIH SVGREISSSA
AKQPSPPPSV PVAKETKKET KKEPAPRKTG ANWFRWLMGK GKNEAHLPDD KNKSIVWDEQ
KQRWVNLDEP EEESKPPPPP PTGFPKAPQA AAPGPAGPPS APAVNIFSRR AAGSRARYVD
VLNPGGTKSS GAVPAPSDLF APLAPMPMPA NVFVPNSVAE EPQPMEGSGA TEHTPAVNQT
NTDPAAAEPE YLNPAILPPG SGLPVSNLDG SQSGELSRSS SMSSLSREVS QHFNQPITLV
PSGLSLPLMF FILLLLYQSP AVTGSSRPGR IGQRKYPTLK
//
