ID A0A091GM28_9AVES Unreviewed; 706 AA.
AC A0A091GM28;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ATP-dependent zinc metalloprotease YME1L1 {ECO:0000313|EMBL:KFO82336.1};
DE Flags: Fragment;
GN ORFNames=N303_01955 {ECO:0000313|EMBL:KFO82336.1};
OS Cuculus canorus (common cuckoo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cuculiformes; Cuculidae; Cuculus.
OX NCBI_TaxID=55661 {ECO:0000313|EMBL:KFO82336.1, ECO:0000313|Proteomes:UP000053760};
RN [1] {ECO:0000313|EMBL:KFO82336.1, ECO:0000313|Proteomes:UP000053760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N303 {ECO:0000313|EMBL:KFO82336.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR EMBL; KL448311; KFO82336.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091GM28; -.
DR STRING; 55661.A0A091GM28; -.
DR MEROPS; M41.026; -.
DR Proteomes; UP000053760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR23076:SF37; ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000313|EMBL:KFO82336.1};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:KFO82336.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053760};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..441
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 17..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO82336.1"
FT NON_TER 706
FT /evidence="ECO:0000313|EMBL:KFO82336.1"
SQ SEQUENCE 706 AA; 79019 MW; 4A324E0700FECF70 CRC64;
ATVPLSHLIN AFHSPKSSTA TANTASVKPV QRDASPEHDP QKSESVLNLR DLGLSDLKAN
QFKELVNRLL PGYCVENKVS SQWHTSYISA ESFFENKHGF VDVFSVLRSS CLYRQHPSPL
HNFCSDVRCW PVYIQSRNFK TLRSRARRLQ STSEQFTETK SSLSSLLKGF ILRKRRIDVE
NLDALMKTKN IPEAHQDAFK TGFAEGFLKA QVFLQKTLDS LRRSRLLSFF LFVLCFYLAI
YSSFLPGKVR FRTSSIFDAA VDPIQLKNVT FEHVKGVEEA KQELQEVVEF LKNPHKFTVL
GGKLPKGILL VGPPGTGKTL LARAVAGEAD VPFYYASGSE FDEMFVGVGA SRIRSLFREA
KANAPCVIFI DELDSVGGKR IESPMHPYSR QTINQLLAEM DGFKPNEGVV IIGATNFPEA
LDNALIRPGR FDMQVTVPKP DVRGRTEILK WYLNKIKYDP SVDPEIIARG TVGFSGAELE
NLVNQAALKA AVDGKDMVTM KELEFSKDKI LMGPERRSVE IDEKNKTITA YHESGHAIIA
YYTKDAMPIN KATIMTRGTT LGHVSLLPEN DRWSETKSQL LAQMDVCMGG RVAEELIFGS
DHITTGASSD FDNATKIAKL MVTRFGMSEK LGVMTYTDTG KVSPETQSAI EQEVRTLLRE
SYERAKNILK THAKEHKNLA EALLKYETLD AKEIQIVLEG KKLEVR
//
