ID A0A091GSI3_BUCRH Unreviewed; 1931 AA.
AC A0A091GSI3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Myosin-6 {ECO:0000313|EMBL:KFO86541.1};
DE Flags: Fragment;
GN ORFNames=N320_11488 {ECO:0000313|EMBL:KFO86541.1};
OS Buceros rhinoceros silvestris.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO86541.1, ECO:0000313|Proteomes:UP000054064};
RN [1] {ECO:0000313|EMBL:KFO86541.1, ECO:0000313|Proteomes:UP000054064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO86541.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Muscle contraction. {ECO:0000256|ARBA:ARBA00037488}.
CC -!- SUBUNIT: Muscle myosin is a hexameric protein that consists of 2 heavy
CC chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2
CC regulatory light chain subunits (MLC-2).
CC {ECO:0000256|ARBA:ARBA00038612}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KL511489; KFO86541.1; -; Genomic_DNA.
DR Proteomes; UP000054064; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 5.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF11; MYOSIN-6; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 7.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000054064}.
FT DOMAIN 30..79
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 83..778
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 655..677
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1912..1931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 840..1156
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 176..183
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT NON_TER 1931
FT /evidence="ECO:0000313|EMBL:KFO86541.1"
SQ SEQUENCE 1931 AA; 223011 MW; 74ABCBBF709BFA79 CRC64;
MIDMSEFGDA APFLRKSEKE LMKLQTVAFD GKKKCWVPDE KKAYIEAEIT ESSDGKVTVE
TTDGRTLTIK EDDVQSMNPP KFDMIEDMAM LTHLNEASVL YNLKRRYSNW MIYTYSGLFC
VTINPYKWLP VYKPEVVAAY KGKRRSEAPP HIFSIADNAY HDMLRNRENQ SMLITGESGA
GKTVNTKRVI QYFATVAALG EPGKKSVTTR TGGTLEDQII QANPALEAFG NAKTLRNDNS
SRFGKFIRIH FGTTGKLSSA DIEIYLLEKS RVIFQQPGER DYHIFYQILS GKKPELLDML
LVSTNPYDYH FCSQGVVTVD NLDDGEELIA TDQAMDILGF VPDEKYGSYK LTGAIMHFGN
MKFKQRPREE QAEADGTESA DKAAYLMGIN SSDLIKGLLH PRVKVGNEYV TKGQSVEQVL
YAVGALSKAV YDRMFKWLVV RINKTLDTKL PRQFFIGVLD IAGFEIFDFN SFEQLCINFT
NEKLQQFFNH HMFVLEQEEY KKEGIEWVFI DFGMDLQACI DLIEKPLGIL SILEEECMFP
KATDMTFKAK LYDNHLGKSP NFQKPRPDKK RKYEAHFELR HYAGSVPYNI IGWLEKNKDP
LNETVVGIFQ KSSNKLLASL FESYVGADSA DQGGEKKRKK GASFQTVSSL HKENLNKLMT
NLRSTAPHFV RCIIPNESKT PGEMDPFLVL HQLRCNGVLE GIRICRKGFP NRVLYADFKQ
RYRILNPGAI PEDTFVDSRK AAEKLLASLD VDHNQYRFGH TKVFFKAGLL GHLEEMRDER
LAKILTMIQA RARGRLMRIE FQKIVERRDA LLVIQWNIRA FMAVKNWPWM KLYFKIKPLL
KSAETEKEMA NMKEEFLKLK EALEKSEARR KELEEKQVSL VQEKNDLLLQ LQAEQDTLAD
AEERCDLLIK SKIQLEAKVK ELTERVEDEE EMNSELTSKK RKLEDECSEL KKDIDDLEIT
LAKVEKEKHA TENKVKNLTE EMATLDENIS KLTKEKKSLQ EAHQQVLDDL QAEEDKVNTL
SKAKAKLEQQ VDDLEGSLEQ EKKVRMDLER AKRKLEGDLK LTQESVMDLE NDKLQMEEKL
KKKEFEMSQL NSKIEDEQAI VMQLQKKIKE LQARIEELEE ELEAERAARA KVEKQRSDLA
RELEELSERL EEAGGATAAQ LEMNKKREAE FLKLRRDLEE ATLHYEATAA TLRKKHADSV
AEMGEQLDNL QRVKQKLEKE KSELKMEVDD LSSNMEQMAK GKANAEKLCR TYEDHLNEAK
TKLDEMTRLM NDLTTQKTKL QSENGEFIRQ LEEKESLISQ LSRGKTSFTQ QIEELRRQLE
EETKSKNALA HALQAARHDC DLLREQYEEE QEAKAELQRA LSKGNAEVAQ WRTKYETDAI
QRTEELEDAK KKLAARLQEA EEAIEAANAK CSSLEKTKHR LQNELEDMMI DLEKANSAAA
SLDKKQRGFD KMINDWKQKY EESQAELEAS QKEARGLSTE LFKLKNAYEE TLDHLETLKR
ENKNLQEEIS DLTNQISEGN KNLHEIEKTK KQIEQEKSEV QLALEEAEGA LEHEESKTLR
FQLELSQLKA EFERKLSEKE EEMENIRRNQ QRAIDSLQST LDSEARSRNE AIRLKKKMEG
DLNEMEIQLS HANRHAAEAT KSTRGLQMQI KELQVQLDDL GHVNEDLKEQ LAVSDRRNNL
LQSELDELRA LLDQTERGRK VAEHELLEAT ERVNLLHTQN TSLINQKKKL EGDISQMQNE
VEESIQECRN AEEKAKKAIT DAAMMAEELK KEQDTSAHLE RMKKNMEQTI KDLQKRLDEA
EQIALKGGKK QIQKLESRVR ELENELETEL RRNSDAQKGA RKFERRIKEL TYQSEEDKKN
LARMQDLIDK LQLKVKSYKH QAEEAEAQAN LYLSKYRKQQ HDLDDAEERA EIAESQVNKL
RSKSRDIGMK K
//
