ID   A0A091H9V9_BUCRH        Unreviewed;      1480 AA.
AC   A0A091H9V9;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Neurofibromin {ECO:0000313|EMBL:KFO92651.1};
DE   Flags: Fragment;
GN   ORFNames=N320_08807 {ECO:0000313|EMBL:KFO92651.1};
OS   Buceros rhinoceros silvestris.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX   NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO92651.1, ECO:0000313|Proteomes:UP000054064};
RN   [1] {ECO:0000313|EMBL:KFO92651.1, ECO:0000313|Proteomes:UP000054064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO92651.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KL530599; KFO92651.1; -; Genomic_DNA.
DR   Proteomes; UP000054064; Unassembled WGS sequence.
DR   CDD; cd05130; RasGAP_Neurofibromin; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF142; NEUROFIBROMIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00616; RasGAP; 2.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054064}.
FT   DOMAIN          1210..1405
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFO92651.1"
FT   NON_TER         1480
FT                   /evidence="ECO:0000313|EMBL:KFO92651.1"
SQ   SEQUENCE   1480 AA;  167259 MW;  C7FE01622CF60E23 CRC64;
     LPIKAAQQNT HTKVSTEHNK ECLINISKYK FSLVISGLTN ILKNVNNMRI FGETAEKNLY
     LSQLIILDTL EKCLAGQPKD TMRLDETMLV KQLLPEICHF IHTYREGNQH AAELRNSASG
     VLFSLSCNNF NAVFSRISTR LQELTVCSED NADVHDIELL QYISVDCSKL KRLLQETVFK
     FKALKKVAQL AVINSLEKAF WNWVENYPDE FTKLYQTPQT DMADCAEKLF DLVDGFAEST
     KRKAAVWPLQ IILLVLCPEI IQDIVKDVVE ETKMNKKLFL DNLRKALAGH SGSRQLTESA
     AIACVKLCKA STYINWEDNS VIFLLVQSMV VDLKNLLFNP SKPFSRGNQN ADVDLMIDCL
     VSCFRINPHN NQHFKICLAQ NSPSTFHYVL VNSLHRIITN SALDWWPKID AVYCHSVELR
     SMFSETLHKA IQGCGAHPAI RMTPSLTFKE KMTSLKFKEK PTDLETRSYK FLLLSLVKLI
     HADPKLLLCN PRKQGPETQG STAELITGLV QLVPQSSMPD IAQEAMEALL VLHQLDSIDL
     WNPDAPIETF WEISSQMLFY ICKKLTSHQM LSSTEILKWL REILICRNKF LLKNKQSDRS
     SCNFLFLYDV SGGGTSQISL DHEEMIRCAP GATLRKGKGN SSMESTAGCS GTPICRQAQT
     KLEVALYMFL WSPDIEAVLV AMSCFRHLCE EADIRCGVDE VSVHNFLPNY NTFMEFASVS
     NMMSTGRAAL QKRVMALLRR IEHPTAGNTE AWEDTHAKWE QATKLILNYP KTKMEDGQVT
     ESLHKTIVKR RMSHVSGGGS IDLSDTDSLQ EWINMTGFLC ALGGVCLQHR SNAGLATYSP
     PMGPVNERKG SMISMVSTEG NAETPVSKFI DRLLTLMVCN HEKVGLQIRT NIKDLVGLEL
     SPALYPMLFN KLKNTISKFF DSQGQVLLTE TNTQFVEQTI AIMKNLLDNH TEGSSEHLGQ
     ASIETMMLNL VRYVRVLGNL VHAIQIKTKL CQLVEVMMER RDDLSFCQEM KFRNKMVEYL
     TDWVMGTSNQ ATDEDVKCLT RDLDQASMEA VVSLLAGLPL QPEEGDGVEL MEAKSQLFLK
     YFTLFMNLLN DCSEVEDESA QTGGRKRGMS RRLASLRHCT VLAMSNLLNA NVDSGLMHSI
     GLGYHKDLQT RATFMEVLTK ILQQGTEFDT LAETVLADRF ERLVELVTMM GDQGELPIAM
     ALANVVPCSQ WDELARVLVT LFDSRHLLYQ LLWNMFSKEV ELADSMQTLF RGNSLASKIM
     TFCFKVYGAT YLQKLLEPLL RTVITSSEWQ HVSFEVDPTR LEPTESLEEN QRSLLQMTEK
     FFHAIINSSS EFPPQLRSVC HCLYQVVSQR FPQNSIGAVG SAMFLRFINP AIVSPYEAGI
     LDKKPPPRIE RGLKLMSKIL QSIANHVLFT KEEHMRPFND FVKSNFEAAR RFFLDIASDC
     PASDTVNHSL SFISDGNVLA LHRLLWNNQE KIGQYLSSNR
//