ID A0A091HAT0_BUCRH Unreviewed; 212 AA.
AC A0A091HAT0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Visual system homeobox 2 {ECO:0000256|ARBA:ARBA00014891};
DE AltName: Full=Ceh-10 homeodomain-containing homolog {ECO:0000256|ARBA:ARBA00030203};
DE AltName: Full=Homeobox protein CHX10 {ECO:0000256|ARBA:ARBA00031274};
DE Flags: Fragment;
GN ORFNames=N320_00846 {ECO:0000313|EMBL:KFO84503.1};
OS Buceros rhinoceros silvestris.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO84503.1, ECO:0000313|Proteomes:UP000054064};
RN [1] {ECO:0000313|EMBL:KFO84503.1, ECO:0000313|Proteomes:UP000054064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO84503.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the paired homeobox family.
CC {ECO:0000256|ARBA:ARBA00005733}.
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DR EMBL; KL504944; KFO84503.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091HAT0; -.
DR Proteomes; UP000054064; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR023339; CVC.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR003654; OAR_dom.
DR PANTHER; PTHR46892; VISUAL SYSTEM HOMEOBOX 2; 1.
DR PANTHER; PTHR46892:SF1; VISUAL SYSTEM HOMEOBOX 2; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF03826; OAR; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51496; CVC; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS50803; OAR; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000054064};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Vision {ECO:0000256|ARBA:ARBA00023305}.
FT DOMAIN 1..55
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 57..110
FT /note="CVC"
FT /evidence="ECO:0000259|PROSITE:PS51496"
FT DOMAIN 153..166
FT /note="OAR"
FT /evidence="ECO:0000259|PROSITE:PS50803"
FT DNA_BIND 3..56
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 175..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO84503.1"
FT NON_TER 212
FT /evidence="ECO:0000313|EMBL:KFO84503.1"
SQ SEQUENCE 212 AA; 24075 MW; 6B0ACF02384D0510 CRC64;
RTIFTSYQLE ELEKAFNEAH YPDVYAREML AMKTELPEDR IQVWFQNRRA KWRKREKCWG
RSSVMAEYGL YGAMVRHSIP LPESILKSAK DGIMESCAPW LLGMHKKSLE AAAEAGRKTE
VERQALSKLD KGDKDERGLD PKTTISQEEL RENSIAALRA KAQEHSTKVL GTIVGDTPAL
GRKPETGEEV AVAEDERQME KLNSSQKAEK LI
//
