ID A0A091HGC4_BUCRH Unreviewed; 426 AA.
AC A0A091HGC4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Multidrug and toxin extrusion protein 2 {ECO:0000313|EMBL:KFO86423.1};
DE Flags: Fragment;
GN ORFNames=N320_06349 {ECO:0000313|EMBL:KFO86423.1};
OS Buceros rhinoceros silvestris.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Bucerotiformes; Bucerotidae; Buceros.
OX NCBI_TaxID=175836 {ECO:0000313|EMBL:KFO86423.1, ECO:0000313|Proteomes:UP000054064};
RN [1] {ECO:0000313|EMBL:KFO86423.1, ECO:0000313|Proteomes:UP000054064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N320 {ECO:0000313|EMBL:KFO86423.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199}.
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DR EMBL; KL511042; KFO86423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091HGC4; -.
DR Proteomes; UP000054064; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206:SF270; MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054064};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..426
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012226827"
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO86423.1"
FT NON_TER 426
FT /evidence="ECO:0000313|EMBL:KFO86423.1"
SQ SEQUENCE 426 AA; 45902 MW; BD2DC5D3A397E7C6 CRC64;
FVAQLLGLLI SVVSSIFCGH LGKAELDAVT LAVSVINVTG ISIGSGLASA CDTLMSQTYG
GKNLKQVGTI LQRGILILLL CCFPCWALFI NTEQILLLMR QDPEVSRLTQ VYVMIFIPAL
PAAFLYQLQT RYLLSQAIIL PQVLTGIAAN VLNVAMNAFF LYALKLGMVG SAWANTVSQY
TQAILLFLYV WWKKIHVETW GGWTRDCLLD WGSFIRLAVP GMLMMCIEWW TFEIGSFLAG
LLSVVELGAQ SVIYELSSAA YMVPLGFSVA ASVRVGNALG SGDVLQAKTS CITALLCTGV
FAVVVATLLG TLKDVVGYIF TNDKEIVVLV SKVMIIFAPF HLFDATAATC GGVLRGTGKQ
KLGAIANAIG YYAIGLPIGL SLMFAAKMGV LGLWVGMIVC ISLQALSFSA FVVRMDWKKA
AEEVRL
//
