ID A0A091HK02_CALAN Unreviewed; 1524 AA.
AC A0A091HK02;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Brain-specific angiogenesis inhibitor 1 {ECO:0000313|EMBL:KFO95397.1};
DE Flags: Fragment;
GN ORFNames=N300_02737 {ECO:0000313|EMBL:KFO95397.1};
OS Calypte anna (Anna's hummingbird) (Archilochus anna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC Trochilidae; Calypte.
OX NCBI_TaxID=9244 {ECO:0000313|EMBL:KFO95397.1, ECO:0000313|Proteomes:UP000054308};
RN [1] {ECO:0000313|EMBL:KFO95397.1, ECO:0000313|Proteomes:UP000054308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N300 {ECO:0000313|EMBL:KFO95397.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL217465; KFO95397.1; -; Genomic_DNA.
DR STRING; 9244.A0A091HK02; -.
DR Proteomes; UP000054308; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
DR CDD; cd15990; 7tmB2_BAI1; 1.
DR Gene3D; 1.25.40.610; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 5.
DR InterPro; IPR043838; AGRB_N.
DR InterPro; IPR032471; GAIN_dom_N.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR008077; GPCR_2_brain_angio_inhib.
DR InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR12011:SF39; ADHESION G PROTEIN-COUPLED RECEPTOR B1; 1.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF19188; AGRB_N; 1.
DR Pfam; PF16489; GAIN; 1.
DR Pfam; PF02793; HRM; 1.
DR Pfam; PF00090; TSP_1; 5.
DR PRINTS; PR01694; BAIPRECURSOR.
DR PRINTS; PR00249; GPCRSECRETIN.
DR PRINTS; PR01705; TSP1REPEAT.
DR SMART; SM00008; HormR; 1.
DR SMART; SM00209; TSP1; 5.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 5.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50092; TSP1; 5.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 893..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 931..950
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 962..980
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1001..1020
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1040..1063
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1084..1106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 520..590
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 896..1137
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 276..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1380..1411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1445..1490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1445..1469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO95397.1"
FT NON_TER 1524
FT /evidence="ECO:0000313|EMBL:KFO95397.1"
SQ SEQUENCE 1524 AA; 170096 MW; A88BD36D75D37483 CRC64;
CTTLVQGKFF GYFSSFAVFP LNSSLCSWII QNPDPRRYTL YMKILKPTGG CDHQHIRTYQ
FDSFLESTRT YLGMESFDDV LKLCDGSTRF AFLQSNKQFL QMKQTSPPGV ETWPVRWKPI
KAQERDFSVE YLVVGNRNPS KAACQMLCKW LDACLAISSS SHPCGIMQTP CSCSGGEVLD
QASEILGLNR KKEDCYKDGI YLENCMSSPK DSSGVDFLGG WNSWSAWGDC TKDCGGGLQT
RMRTCKPLPK EGLVCEGVLE EGRLCNRKAC NTNGRYNSRS QSLRSTDNRK REDTEELQHY
GYPAPQIGDP AAEEWSPWSV CSTTCGEGWQ TRTRFCVSSS YSTQCSGPLR EQRQCNNSAV
CPVHGTWDEW SPWSLCSSTC GRGYRDRTRT CKPPQFGGNP CEGPEKQTKF CNIALCPVDG
NWNEWSSWSS CSASCSNGTQ QRTRECNGPS YGGAECQGHW VETRDCFLRQ CPDDGKWQAW
GVWGSCTATC GGGTQRRDRV CYGPFFGGET CQGPKEEYKQ CNDRKCPEPH EICDEETVAS
VVWKETPAGD AAAVRCPRNA TGLILRRCIL DEEGIAYWEP PTYIKCVSID YRNIQMMTRD
HLAKAQRGLM GDGLSEVLQN LVEISQDGTS YSGDLLSTID VLRNVTEIFR RAYHSPTSGD
VQNFVQIISN LLSEENREKW EEAQLIGPNA KELFRLVEDF IDVIGFRMKD FRDSYQVTDN
LVLGIHKLPA NAATDITFPM KGWRGMVDWA KNSEDKVTVS KSILSSGLTA SDDSSVFVVG
TVLYRNVGNI LSLQRNSTVL NSKVISVTVK PLPRSLLTPL EIEFSHLYNG TTNQTCILWD
ETDGSSDGGC VPASSRQHLC SAVDSTKVMC DCVQLDLVVL VVNLSWQCNM EKVLVPSVTL
IVGCGVSSLT LLLLIIIYVS VWRYIRSERS VILINFCLSI ISSNALILIG QTQTRNKVIC
TLVAAFLHFF FLSSFCWVLT EAWQSYMAVT GRLRNRIIRK RFLCLGWGLP ALVVAISVGF
TKAKGYGTVN YCWLSLEGGL LYAFVGPAAA VVLVNMVIGI LVFNKLVSKD GITDKKLKER
AGASLWSSCV VLPLLALTWM SAVLAITDRR SALFQILFAV FDSLEGFVIV MVHCILRREV
QDAVKCRVVD RQEEGNGDSG GSFQNGHAQL MTDFEKDVDM ACRSVLNKDI TTCRTSTITG
TLKRPSLPDE EKLKLNHQKG SSNFNSLPAN VSKMHLQGSP HYLGAINLNE FSNHSLTLKK
DKNQPPKSIY ICDGDIFKKL DSELSRAQEQ TLDTSYVILP TNTSTLRAKP PKDESKYSIN
IDQMPQTRLI HLSMATDPGF VVKSPPREPV TMTCSEVQGS SMIQQQQQQL ASQNISNESQ
IPNSLVDTGD SGNSGVVSKS ETVSTLSMSS LERRKSRYAE LDFEKIMHTR KRHQDMFQDL
NRKLQHAEKE KESPTTDSKQ EKQQTPNKRP WEGIRKVQSP PSWVKKDMEP VAQSPLELKT
VEWEKTGATI PLVGQDIIDL QTEV
//
