ID A0A091HPS8_CALAN Unreviewed; 1428 AA.
AC A0A091HPS8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Peroxidasin {ECO:0000313|EMBL:KFO97861.1};
GN ORFNames=N300_08587 {ECO:0000313|EMBL:KFO97861.1};
OS Calypte anna (Anna's hummingbird) (Archilochus anna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC Trochilidae; Calypte.
OX NCBI_TaxID=9244 {ECO:0000313|EMBL:KFO97861.1, ECO:0000313|Proteomes:UP000054308};
RN [1] {ECO:0000313|EMBL:KFO97861.1, ECO:0000313|Proteomes:UP000054308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N300 {ECO:0000313|EMBL:KFO97861.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL217679; KFO97861.1; -; Genomic_DNA.
DR STRING; 9244.A0A091HPS8; -.
DR Proteomes; UP000054308; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0140825; F:lactoperoxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd05745; Ig3_Peroxidasin; 1.
DR CDD; cd05746; Ig4_Peroxidasin; 1.
DR CDD; cd09826; peroxidasin_like; 1.
DR Gene3D; 6.20.200.20; -; 1.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR047018; Peroxidasin_Ig-like3.
DR InterPro; IPR034828; Peroxidasin_Ig-like4.
DR InterPro; IPR034824; Peroxidasin_peroxidase.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR PANTHER; PTHR11475:SF75; PEROXIDASIN HOMOLOG; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF01463; LRRCT; 1.
DR Pfam; PF00093; VWC; 1.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SMART; SM00406; IGv; 3.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00214; VWC; 1.
DR SUPFAM; SSF57603; FnI-like domain; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 4.
DR PROSITE; PS51450; LRR; 3.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
DR PROSITE; PS01208; VWFC_1; 1.
DR PROSITE; PS50184; VWFC_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR619791-2};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 194..280
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 290..376
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 381..468
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 469..558
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1361..1419
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT COILED 1337..1364
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 1022
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ SEQUENCE 1428 AA; 161207 MW; B82786DFC571B296 CRC64;
MLQRIPNLSS KAALRDLRFN RIKEIQPGEF RRLKNLNTLL LNNNQIKRIP SGAFEDLENL
KYLYLYKNEI QSIDRQAFKG LASLEQLYLH FNQIETLEPE SFTHLPKLER LFLHNNRIAH
LTPGTFSHLE SMKRLRLDSN ALHCDCEILW LAELLKTYAE SGNAQAAATC EYPRRIQGRS
VATITPEELN CERPRITSEP QDVDVTSGNT VYFTCRAEGN PKPEIIWLRN NNELSMKEDS
RLNLLDDGTL MIQNTQETDQ GIYQCMAKNV AGEVKTQEVT LRYFESPARP SFVIQPQNTE
VLVGESVTLE CSAAGHPQPR ITWTKGDRTP LPSDPRITIT PSGGLYIQNV KQEDSGEYTC
FATNSIDNIH ATAYIIVQAL PQFTVTPQDK TVIEGQTVDF PCEAQGYPQP VIAWTKGGGQ
LSVDRRHLVL SSGTLRISRV ALHDQGQYEC QAVNIIGSQR IVVYLTIQPR VTPVFASVPS
DMTVEVGTNV QIPCSAQGEP EPVITWNKDG VQVTESGKFH VSPEGFLTIR DVGTADEGRY
ECVARNTIGY SSVSMVLSVN VPNVSRNGDP FVQTSIVEAI ATVDRAINST RTHLFDSRPR
SPNDLLALFR YPRDPYTVEQ ARAGEIFERT LQLIQDHVQD GLMVDLNGTS YHYNDLVSPQ
YLNLIANLSG CTAHRRVNNC SDMCFHQKYR THDGTCNNLQ HPMWGASLTA FERLLKSVYE
NGFNLPRGIE PRRLSNGYPL PMPRLVSTTL IGTETITPDD QYTHMLMQWG QFLDHDLDLT
VAALSEARFS DGQHCSSVCT NDPPCFSIMI PPNDPRVRNG ARCMFFVRSS PVCGSGMTSL
LMNSVYPREQ INQLTSYIDA SNVYGSSDHE ALEIRDLASQ RGLLRQGIVQ RSGKPLLPFA
TGPPTECMRD ENESPIPCFL AGDQRSNEQL GLTSIHTLWF REHNRIATEL LKLNPHWDGD
TIYHETRKIV GAEMQHITFS HWLPKIFGEV GMKMLGEYKG YDPSVNSGIT NEFATAAFRF
GHTLINPFLY RLDENFEPIP QGHLPLHKAF FSPFRIVNEG GIDPLLRGLF GVAGKMRVPS
QLLNTELTER LFSMARTVAL DLAAMNIQRG RDHGIPPYHD FRVYCNLSSA QTFEDLKNEI
KNPEIREKLS RLYGSPLNID LFPALMVEDL VPGSRLGPTL MCLLSTQFRR IRDGDRLWYE
NPGVFTPAQL TQIKQTSLAR VLCDNGDNIT RVQHDVFKVA EFPHGYSSCE DIPKLDLRMW
QDCCEDCRTR GQFNAFSYHF RGRRSLDYSF QEDKPLKNMK ISKAVSSVKQ SKYFRNATST
SKENSNMPAV NDFKEFVLEM QKTISSLRNQ IKKLESRLSK TDCTDEKGKS YSSNETWKRD
PCTVCECKVG QITCFVESCP PADCEAPVKV KGDCCPVCLK QNINRKEP
//
