ID A0A091HWQ4_CALAN Unreviewed; 817 AA.
AC A0A091HWQ4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Ras GTPase-activating protein 1 {ECO:0000313|EMBL:KFO99567.1};
DE Flags: Fragment;
GN ORFNames=N300_13719 {ECO:0000313|EMBL:KFO99567.1};
OS Calypte anna (Anna's hummingbird) (Archilochus anna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC Trochilidae; Calypte.
OX NCBI_TaxID=9244 {ECO:0000313|EMBL:KFO99567.1, ECO:0000313|Proteomes:UP000054308};
RN [1] {ECO:0000313|EMBL:KFO99567.1, ECO:0000313|Proteomes:UP000054308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N300 {ECO:0000313|EMBL:KFO99567.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL217827; KFO99567.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091HWQ4; -.
DR STRING; 9244.A0A091HWQ4; -.
DR Proteomes; UP000054308; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd08400; C2_Ras_p21A1; 1.
DR CDD; cd13260; PH_RASA1; 1.
DR CDD; cd05391; RasGAP_p120GAP; 1.
DR CDD; cd10354; SH2_Cterm_RasGAP; 1.
DR CDD; cd11788; SH3_RasGAP; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR035842; RasGAP_C_SH2.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR035652; RasGAP_SH3.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR10194:SF146; RAS GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00239; C2; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00323; RasGAP; 1.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 49..111
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 121..211
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 244..347
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 347..460
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 518..712
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFO99567.1"
FT NON_TER 817
FT /evidence="ECO:0000313|EMBL:KFO99567.1"
SQ SEQUENCE 817 AA; 94129 MW; AEF589B42AA03A86 CRC64;
RIIAMCGDYY IGGRRFASLS DLIGYYSHVS CLLKGEKLLF PVAPPEPVED RRRVRAILPY
TKVPETDEIS FLKGDMFIVH NELEDGWMWV TNLRTDEQGL IVEDLVEEVG REEDPHEGKI
WFHGKISKQE AYNLLMTVGQ VCSFLVRPSD NTPGDYSLYF RTSENIQRFK ICPTSNNQFM
MGGRYYNSIA DIIEHYRKEQ IVEGYYLKDP VPMQHQEQVL NDTVDGKEIY NTIRRKTKDA
FYKNIVKKGY LLKKSKGKRW KNLYFILEGN DAQLIYFESE KRATKPKGLI DLSVCSVYGV
HDSLFGRPNC FQIVVQHFSE EHYIFYFAGE TPEQAQDWMK ALQMFCSLRK TSPGTSNKRL
RQVSSLILHV EEAHTLPVKH FTNPYCNIYL NSVQVAKTHI REGQNPVWSE EFVFDDLSSD
INRFEISLSN KTKKSKDPDI LFMRCQLSRL QKGHATDEWF QLSSHVPLKG IEPGSLRVRA
RYSMEKIMPE EEYNEFKELI LQKELHVVYA LSHVCGQDRT LLAGILLKIF LHEKLESLLL
RTLNDREISM EDEATTLFRA TTLASTLMEQ YMKATATSFV HHALKDSILK IMESKQSCEL
NPSKLEKNED VNTNLAHLLS ILSELVEKIF MAAEILPPTL RYIYGCLQKS VQNKWPANTT
MRTRVVSGFV FLRLICPAIL NPRMFNIISD SPSPTAARTL TLVAKSVQNL ANLVEFGAKE
PYMEGVNPFI KSNKHRMIMF LDELGNVPEL PDTTEHSRTD LSRDLAALHE ICVAHSDELR
TLSNERGVMQ HVLKKLLAIT ELLQQKQNQY SVSNNIR
//
