ID   A0A091I8H8_CALAN        Unreviewed;       484 AA.
AC   A0A091I8H8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=Protein tweety homolog {ECO:0000256|RuleBase:RU361114};
DE   Flags: Fragment;
GN   ORFNames=N300_09827 {ECO:0000313|EMBL:KFP04532.1};
OS   Calypte anna (Anna's hummingbird) (Archilochus anna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC   Trochilidae; Calypte.
OX   NCBI_TaxID=9244 {ECO:0000313|EMBL:KFP04532.1, ECO:0000313|Proteomes:UP000054308};
RN   [1] {ECO:0000313|EMBL:KFP04532.1, ECO:0000313|Proteomes:UP000054308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N300 {ECO:0000313|EMBL:KFP04532.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable chloride channel. {ECO:0000256|RuleBase:RU361114}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU361114};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU361114}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the tweety family.
CC       {ECO:0000256|ARBA:ARBA00009849, ECO:0000256|RuleBase:RU361114}.
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DR   EMBL; KL218366; KFP04532.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091I8H8; -.
DR   STRING; 9244.A0A091I8H8; -.
DR   Proteomes; UP000054308; Unassembled WGS sequence.
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-UniRule.
DR   CDD; cd07912; Tweety_N; 1.
DR   InterPro; IPR006990; Tweety.
DR   PANTHER; PTHR12424:SF4; PROTEIN TWEETY HOMOLOG 3; 1.
DR   PANTHER; PTHR12424; TWEETY-RELATED; 1.
DR   Pfam; PF04906; Tweety; 1.
PE   3: Inferred from homology;
KW   Chloride {ECO:0000256|RuleBase:RU361114};
KW   Chloride channel {ECO:0000256|RuleBase:RU361114};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|RuleBase:RU361114};
KW   Ion transport {ECO:0000256|RuleBase:RU361114};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361114};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361114};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361114};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361114}.
FT   TRANSMEM        6..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361114"
FT   TRANSMEM        39..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361114"
FT   TRANSMEM        170..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361114"
FT   TRANSMEM        198..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361114"
FT   TRANSMEM        348..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361114"
FT   REGION          375..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          450..484
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..391
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        450..471
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFP04532.1"
FT   NON_TER         484
FT                   /evidence="ECO:0000313|EMBL:KFP04532.1"
SQ   SEQUENCE   484 AA;  53858 MW;  F9FF7CFA6F224249 CRC64;
     QALLLLGGIA LSCLALDLLF LLFYSFWLCC RHRKSEEHLN ADCCCTAWCV IIATLVCSAG
     IAVGFYGNGE TSDGIHRLTY SLRHANRTVA GVQDRVLDTA VALNQTVEPN LLVLEEMFTK
     QTDYLHIIQK LQGLLDELLR QTTEIPFWKN EELSLEELAI QIDLYDWYRW LGYLGLLLFH
     VLICLLVLFG LIRNSRAILI GVCLLGVFAL IVSWASLGLE LAVAVGSSDF CVNPDAYVSQ
     VAEENAVLSA DTLRYYMSCS AGYPNPFQQK LSGSHKALVE MQDDVMELMR SASRDHPTSK
     EYLTRIQEVL NATEINLQQL TALVDCRSLH LDYVQALTGF CYDGVEGLIY LVLFSFVTAL
     MFSSIVCSIP HTWQQKRSSD DDGEEESAVQ GSRQTHDNLY RVHMPSLYSC GSSYGSETSI
     PAAAHTVSNA PVTEYMSQNA NFQNPRCENT PLIGRESPPP SYTSSMRAKY LATNQPRPDA
     GSVH
//