ID   A0A091I8Y4_CALAN        Unreviewed;       313 AA.
AC   A0A091I8Y4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Aquaporin-4 {ECO:0000256|ARBA:ARBA00040878};
DE   Flags: Fragment;
GN   ORFNames=N300_12919 {ECO:0000313|EMBL:KFP03830.1};
OS   Calypte anna (Anna's hummingbird) (Archilochus anna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC   Trochilidae; Calypte.
OX   NCBI_TaxID=9244 {ECO:0000313|EMBL:KFP03830.1, ECO:0000313|Proteomes:UP000054308};
RN   [1] {ECO:0000313|EMBL:KFP03830.1, ECO:0000313|Proteomes:UP000054308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N300 {ECO:0000313|EMBL:KFP03830.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC       {ECO:0000256|ARBA:ARBA00004415}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004415}. Cell projection
CC       {ECO:0000256|ARBA:ARBA00004316}. Endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004608}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC       {ECO:0000256|ARBA:ARBA00006175, ECO:0000256|RuleBase:RU000477}.
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DR   EMBL; KL218275; KFP03830.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091I8Y4; -.
DR   STRING; 9244.A0A091I8Y4; -.
DR   Proteomes; UP000054308; Unassembled WGS sequence.
DR   GO; GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
DR   GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR   GO; GO:0015267; F:channel activity; IEA:InterPro.
DR   CDD; cd00333; MIP; 1.
DR   Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR034294; Aquaporin_transptr.
DR   InterPro; IPR000425; MIP.
DR   InterPro; IPR022357; MIP_CS.
DR   NCBIfam; TIGR00861; MIP; 1.
DR   PANTHER; PTHR19139; AQUAPORIN TRANSPORTER; 1.
DR   PANTHER; PTHR19139:SF34; AQUAPORIN-4; 1.
DR   Pfam; PF00230; MIP; 1.
DR   PRINTS; PR02016; AQUAPORIN4.
DR   PRINTS; PR00783; MINTRINSICP.
DR   SUPFAM; SSF81338; Aquaporin-like; 1.
DR   PROSITE; PS00221; MIP; 1.
PE   3: Inferred from homology;
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023139};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054308};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000477};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT   TRANSMEM        32..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        61..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFP03830.1"
FT   NON_TER         313
FT                   /evidence="ECO:0000313|EMBL:KFP03830.1"
SQ   SEQUENCE   313 AA;  33733 MW;  D56DA25007E41FB4 CRC64;
     SKCGRLFKCE SIMVAFKGVW TQPFWKAVSA EFLAMLIFVL LSLGSTINWG GAENPLPVDM
     VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SLAKSVFYIL AQCLGAIVGA
     GILYLITPPS VVGGLGVTAV HEDLSAGHGL LVELIITFQL VFTIFASCDS KRNDVTGSVA
     LAIGFSVAIG HLFAINYTGA SMNPARSFGP AVIMGRWENQ WVYWVGPIIG AVLAGALYEY
     VYCPDVELKR RFKDVFSKAT QPSKGKYIEV DDNRSHVETD DLILKPGIVH VIDIDRGEDK
     KGRDPSSEVL SSV
//