ID A0A091IHB4_CALAN Unreviewed; 4041 AA.
AC A0A091IHB4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Dynein heavy chain 3, axonemal {ECO:0000313|EMBL:KFP07994.1};
DE Flags: Fragment;
GN ORFNames=N300_06906 {ECO:0000313|EMBL:KFP07994.1};
OS Calypte anna (Anna's hummingbird) (Archilochus anna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC Trochilidae; Calypte.
OX NCBI_TaxID=9244 {ECO:0000313|EMBL:KFP07994.1, ECO:0000313|Proteomes:UP000054308};
RN [1] {ECO:0000313|EMBL:KFP07994.1, ECO:0000313|Proteomes:UP000054308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N300 {ECO:0000313|EMBL:KFP07994.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
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DR EMBL; KL218765; KFP07994.1; -; Genomic_DNA.
DR STRING; 9244.A0A091IHB4; -.
DR Proteomes; UP000054308; Unassembled WGS sequence.
DR GO; GO:0005930; C:axoneme; IEA:UniProt.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF1; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054308}.
FT DOMAIN 1351..1490
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1991..2138
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 745..775
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2830..2895
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP07994.1"
FT NON_TER 4041
FT /evidence="ECO:0000313|EMBL:KFP07994.1"
SQ SEQUENCE 4041 AA; 461891 MW; 0F5EDE71B9D40652 CRC64;
EDDSVNNMTN PNQLPEVSSL PASTSGAASE VDQPVLESTY YPPLMQQMSW TQAAPFKEQR
FCRGPSDSIA NNYSLTARDL TMKNLRKIKS SSVRGTSQGA VQQTSSLCHT CPQMTASVFP
KLFFLVFFPP TSTPISSGSW NPTPLHAPAH IPELCYTDNQ PLTPEEQFVV MHLIEKEISE
QEKPPSATEI ERYCHYIHHE VREDMVIPLD KEVMNVILEH IPPLLLANPD LKNLLASLKE
EIKAGYIISI MKATVDYILL DPEERERLSI GSTPRPFPLR VVRAPVPWHK SYKAMKSWNE
KNLFIVNPLM FTLQQLWFSD YSHLRFVRTQ ELLSRGLPML PAQFQEVTQR HCMEARHILQ
NKWIPACASI LANQKKKWLH FAPKKDSDSS QQVESYFNSV AALMSLKLRE MVINSLEDFL
VFFNIHKDGN DFAEPYQERE FFISPILTVK LNVEEPKIVF EPPLEEYWHL ISRCFREILQ
SAEELPKVER FLFPELKRDD LTLRTVRPDE SLFTERVNKL EKVFERNILG PQKYLNVYRK
YNNLLDNNAQ QDVTDFLKED TSLEALTEKI DSLRELKREI ASMRITASLA LFSLDAAHLN
KDLCNRTQNL IDRLVEFAVM ENREFNNRIC DEYDLIAKKM NEVPQNTEEL VEYDAYLKKS
SEVTVFDLKK KVAEAAHRLK FLMDYAFFRW PKEIETIFES SREKSRERRQ NAEMALLKRC
SEFEEILQRY DEEIQSYKTV DVISVEEIEY NAESFKELNK NLDNALTEYD AINKEEELLG
REKSQYPLLQ AILASKQPFE QLWVTAHDFH TKSEDWMNES LQKLNAEEIT EEVDGMWRTM
YKLSKTFAEL PGPKRLAETM RTKINEFKEH LPVMSVVCNR GMKERHWEQI SEVVGSQIKP
DETTTFADML KFELFKYIEQ LEPIGASASK EYSLEKSIEK MKLEWVSINF SLVQYRDTNT
SILSAVDDIQ LLLDDHLIKI QTMCGSPFIK PIETECRAWK DKLSLMQDII DSWLKCQATW
LYLEPIFSSE DIVAQMPEEG RKFGVVNTYW HTIMAQVVKD PKVLAAAEQP MMLNRLQEAN
ALLEDVQKGL NTYLEKKRLY FPRFFFLSND ELLEILSETK DPLRVQPHLK KCFEGIAKLE
FTEGLEILGM ISSENEIVSF INKIYPVNAK GMVEKWLLQV EEMMLASVKQ VIQDGVKGYV
EVPRKTWVLQ WPGQVVICVS SIYWTQEVCE AITNGTLPDY LEKSNLQIAD IVELVRGKLS
SGARLTLGAL TVIDVHARDV VAKLVEDRVT DLNDFHWISQ LRYYWEEDDV IVRMITTEAK
YGYEYLGNSS RLVITPLTDR CYRTLMGALK LNLGGAPEGP AGTGKTETTK DLAKALAKQC
VVFNCSDGLD YKAMGKFFKG LAQSGAWACF DEFNRIEVEV LSVVAQQILS IQQAIMRKLK
TFIFEGTEIS LNPTCAVFIT MNPGYAGRAE LPDNLKALFR TVAMMVPDYA LIGEISLYSM
GFLDSRSLAQ KIVATYRLCS EQLSSQHHYD YGMRAVKSVL TAAGNLKLKY PTENESVLLL
RALLDINLAK FLSQDVPLFQ GIISDLFPGV VLPAPDYDLF VQALTENIKK MTLQPVPWFI
EKIIQVYEMM LVRHGFMIVG EPLSGKTCSY KVLAAALGDL YAAKSMDEFA VEYKVINPKA
VTMGQLYGSF DPVSHEWSDG VLATAFREQA SSTTDDRKWI IFDGPVDAVW IENMNTVLDD
NKKLCLMSGE IIQMNSKMSL IFEPADLEEA SPATVSRCGM IYMDSHQLGW KPLKDSYLEK
LPPNLEEEHR EMVNGLFMWL VQPCLDFIHL NCKAFVQTSP IHLSYSLMKL YDCLLDVIKQ
PEEEEKRSMS SQEIIMWLQG LFLFSLVWTV GGIIDADSRK KFDVFYRDLL VGRNSENPCP
ESVKFNRGNS FPDKGSVYDY YIDKHGQWKM WMEYITKEEQ VIAPDAKVSE LIIPTMETAR
QMFFLKTYVE HSVPLLLVGP TGTGKSAITN SFLLQLPKEV YIPSFINFSA RTSASQTQDI
VMSKLDRRKK GLFGPPAGKK AIMFVDDLNM PAKEVYGAQP PIELLRQWID HGHWYDKKDT
SKINITDVLF VSAMGPPGGG RNDITGRFTR HLNVVSICSF DDDILTRIFT AVADWHFSKG
FEPAFLRLGN VMVQATMAIY KSAVANFLPT PSKSHYVFNL RDFSRVIRGV LLCPHTHLKD
EDKLIRLWIH EVYRVFYDRL IDEEDRNVFF QLVQEATSNT FNQSLDKVVG HLSPTGKVSD
DNIRSLFFGD FFLPDSSDKV YDEITDLQQL TAVMEHYLEE YNNMSKAPMP LVMFKFAIEH
ISRICRVLKQ DNGHLLLVGI GGSGRQSATK LATFMNTFEL FQIEITKSYG INEWKDDVKK
VMVKTGVENK NISFLFCDNQ IKDEAFVEDV NMLLNTGDVP SIFPADEKAE IAEKMQNAAR
MENKKIETSP VAMYNFFIER VKKNLHIVLA MSPIGDAFRN RLRMFPSLIN CCTIDWFQTW
PTDALEMVAN KFLEDVELDD DVRKEVVSMC KYFHESVREL SIDYFTILRR HNYVTPTSYL
ELILTFKTLL NRKRQEVDMM RTRYLTGLQK LEFASSQVSE MQKELTDLQP ELIQTSAETD
KMMVQIEKET TEVDAKKELV SADEKEANEA AAVAKAIKDE CEGDLAEAMP ALEAALAALD
TLNPSDISLV KSMQNPPGPV KLVMESICVM KGSKPERKPD PSGSGKMVED YWGPSRKILG
DLKFLESLKT YDKDNIPPAI MKRIREKFID HPDFQPAVIK NVSSACEGLC KWVRAMEVYD
RVAKVVAPKR ERLKEAEEVL DVQMQKLQTK QAELKELLDR LQALNDDFER MNNRKTELEN
NIELCSQKLV RAEQLISGLG GEKERWTEAA RLLGIRYTDL VGDVLLSSGT VAYLGAFTVD
YRLRCQKQWQ DLCIEKNIPC SSDFSLSNTL GDPVKTRAWQ IAGLPIDSFS VDNGIIVSNS
RRWALMIDPQ RQANKWVKNM EKNNTLSVIK LSDAQYVKTL ENAIQLGTPV LLEDIGEELD
AFIEPILLKL TFKQQGVEYM KLGENIIEYS RDFRFYMTTR LRNPHYLPEV AVKVCLLNFM
ITPLGLQDQL LGIVAAKEKP ELEEKKNQLI IESAANKKQL KEIEDKILEV LSSSEGNILE
DETAINVLSS SKELSQEISE KQKIATATEE EIDSTRLGYK PVAVHSAVVF FCISDLANIE
PMYQYSLIWF INLYVQSIAK SEKSEDLEKR IENIIDHFTV SIYNNVCRSL FEKDKLLFSF
LLTVGIMKGK GLIDDEVWRF LLTGGVALDN PHPNPAPDWL SDKSWAEIVR ASNLTNLSGL
MEHVKESFSK WKPIYDSVRP HEEAFPDTWS TLAGLDRMVI LRCLRPDKII PAVQDFIVEN
MGRTFIEPPT FDLGKSYSDS SCCTPLIFIL SPGADPMAGL LKFADDVGMG GTNIQTISLG
QGQGPIAAQM IHEGISRGTW VVLQNCHLAT SWMPTLEKIC EEVIVPENTN DRFRLWLTSY
PSEKFPVSIL QNGIKMTNEP PKGVRANLLR SYFNDPISDP VFFSSCEKAE IWQKLLFGLC
FFHAIVQERR NFGPLGWNIP YEFNESDLRI SMRQIQMFLN EYEEIPFEAL TYLTGECNYG
GRVTDDKDRR LLLSLLSIIY SKDIVQDKYM LAAGDDYYIP PHGPYESYIE YIQSLPITTH
PEVFGLHENA DITKDNQETN QLFQGILLTL PRVAGGGGKS SQETVEDLAQ DILSKLPTSF
DMEEVMKAYP VLYEESMNTV LRQELIRFNR LTEVIRSSLI NLRKAIKGQV LMSSELEDVF
NSMLIGKVPS MWDAKSYPSL KPLGSYVSDL LCRLAFFQEW VKKGPPTVFW LSGFFFTQSF
LTGVLQNYAR KYTIPIDGIG FEFEVMKQEQ TMEKMPEDGA YVRGLFLEGA RWDRESAVIG
ESLPKVLYDP LPVIWLKPGE ISKFLHENIY SCPVYKTSAR RGVLSTTGHS TNYVLSIELP
SDKPQKHWIN RGVAALCQLD D
//
