ID A0A091IJW2_EGRGA Unreviewed; 550 AA.
AC A0A091IJW2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|EMBL:KFP08939.1};
DE Flags: Fragment;
GN ORFNames=Z169_13994 {ECO:0000313|EMBL:KFP08939.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP08939.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP08939.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP08939.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the eIF2D family.
CC {ECO:0000256|ARBA:ARBA00010359}.
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DR EMBL; KK500571; KFP08939.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091IJW2; -.
DR STRING; 188379.A0A091IJW2; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001731; P:formation of translation preinitiation complex; IEA:InterPro.
DR CDD; cd11608; eIF2D_C; 1.
DR CDD; cd11610; eIF2D_N; 1.
DR CDD; cd21156; PUA_eIF2d-like; 1.
DR Gene3D; 3.10.400.20; -; 1.
DR Gene3D; 3.30.780.10; SUI1-like domain; 1.
DR InterPro; IPR039757; EIF2D.
DR InterPro; IPR048247; eIF2D_N.
DR InterPro; IPR039759; eIF2D_SUI1.
DR InterPro; IPR041366; Pre-PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR048248; PUA_eIF2d-like.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR003121; SWIB_MDM2_domain.
DR PANTHER; PTHR12217; EUKARYOTIC TRANSLATION INITIATION FACTOR 2D; 1.
DR PANTHER; PTHR12217:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 2D; 1.
DR Pfam; PF17832; Pre-PUA; 1.
DR Pfam; PF01253; SUI1; 1.
DR SUPFAM; SSF55159; eIF1-like; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR PROSITE; PS50890; PUA; 1.
DR PROSITE; PS50296; SUI1; 1.
DR PROSITE; PS51925; SWIB_MDM2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:KFP08939.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:KFP08939.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119}.
FT DOMAIN 349..433
FT /note="DM2"
FT /evidence="ECO:0000259|PROSITE:PS51925"
FT DOMAIN 457..530
FT /note="SUI1"
FT /evidence="ECO:0000259|PROSITE:PS50296"
FT REGION 202..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP08939.1"
FT NON_TER 550
FT /evidence="ECO:0000313|EMBL:KFP08939.1"
SQ SEQUENCE 550 AA; 61483 MW; 7F670676C40D612D CRC64;
RRKLRTDVAA AFPNLSAEQL TEFIPNKEEL NVIKIHSHKG EAVTVYMNNR NPILFEIEKA
LYPTVYSLWV YPDLLPAFST WPPVLQKLAG GADLMLPGVV VPSSGFPQVE RGTLCAVTLL
GNRAPVAVAV ATMSTAEMLA AGMKGKGFAV LHTYLDHLWE YGDKSYPPTL APLHVDVGDL
SLKERDGCTV LTGKEELNKN RAAETAEHAN TEVQQEAEDS RTPQEQMDAL FSQCFFHALK
CKVKKSDLPL LTSTFLRSHM FSCCPAGQQL DIKKSSYKKF SKFLQCMQHQ KILQVKELNK
GVESIVEVDW KHPDVKAFAV PEGFSSASAA QDSKSEDREQ VYHAPEIIPL YGVSAKMMPL
FQESGHRKGS ILSSSEVRNI IINYVKTNEL VDETNKNLVK VNAILCDCLL DKSEQDEISN
LKWDDLVSRC LERLQPLHQV TFFGQEPVVR KGNVEPIDIT IAQRSSNKKV TIIKNLELYG
LDPQCVANIL QQKVQASATI TPVPGTKDRV QVQIQGNQIH HLAKMLLEEY QLPRKYIQGL
EKAPKLGRKK
//
