ID A0A091IL47_EGRGA Unreviewed; 328 AA.
AC A0A091IL47;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Cathepsin L1 {ECO:0000313|EMBL:KFP09409.1};
DE Flags: Fragment;
GN ORFNames=Z169_07409 {ECO:0000313|EMBL:KFP09409.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP09409.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP09409.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP09409.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; KK500603; KFP09409.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091IL47; -.
DR STRING; 188379.A0A091IL47; -.
DR MEROPS; C01.032; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411:SF57; CATHEPSIN L2; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 20..79
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 108..328
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP09409.1"
FT NON_TER 328
FT /evidence="ECO:0000313|EMBL:KFP09409.1"
SQ SEQUENCE 328 AA; 37204 MW; 1A1BFB30C68C7104 CRC64;
LCLGLAFGAP RPDPDLDGHW QLWKSWHNKA YHEREESWRR VVWEKNLKMI ELHNLDHTLG
KHSYKLGMNQ FGDMTTEEFR QLMNGYAHKK SQRRYRGSQF LEPSFLEVPR SVDWREKGYV
TPVKDQGQCG SCWAFSTTGA LEGQHFRKTG KLVSLSEQNL VDCSRPEGNQ GCNGGLMDQA
FQYVQDNGGI DSEESYPYTA KDDEDCRYKA EYNAANDTGF VDIPQGHERA LMKAVASVGP
VSVAIDAGHS SFQFYQSGVY YEPDCSSEDL DHGVLVVGYG FEGEDVDGKK YWIVKNSWGE
KWGNKGYIYM AKDRKNHCGI ATAASYPL
//
