ID A0A091IP26_EGRGA Unreviewed; 1070 AA.
AC A0A091IP26;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Ubiquitin-protein ligase E3B {ECO:0000313|EMBL:KFP09190.1};
GN ORFNames=Z169_08037 {ECO:0000313|EMBL:KFP09190.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP09190.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP09190.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP09190.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK500582; KFP09190.1; -; Genomic_DNA.
DR RefSeq; XP_009634217.1; XM_009635922.1.
DR AlphaFoldDB; A0A091IP26; -.
DR STRING; 188379.A0A091IP26; -.
DR GeneID; 104123645; -.
DR KEGG; egz:104123645; -.
DR CTD; 89910; -.
DR OrthoDB; 1386at2759; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR45700:SF3; UBIQUITIN-PROTEIN LIGASE E3B; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SMART; SM00015; IQ; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
DR PROSITE; PS50096; IQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Ligase {ECO:0000313|EMBL:KFP09190.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 704..1070
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT COILED 9..36
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 1038
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 1070 AA; 122886 MW; 257AAE4539BC225E CRC64;
MFSASQSSKA QFLDKARQAR EERRELKERE RAAIQIQALI RRFLCRCRLQ REIRREVEDF
FGANESGSSK RSALSIFRIA RKLLFVFNHK EDKERFEKLC RCILNSMDVE NEPKVWYVSL
ALSKDLTLLW IKQIKDVLWF CCEFLKQLKP DILQDSRLVN LHLTMLVTFT DTSTWKILRG
KGETLRPAMN HICANIMGHL NQKGFYSVLQ ILLTNGLARS RPSLSKGSLT AVFSLALRPV
VAAQFSDNLL RSFLIHIMSV PAIMTHLATL TPERLAVIES HDLFRKFILF LSREAQCRDV
CVCLEGSHTL CLLGNLVYLG SLNDKVLEEE TAHFVGVLIH MLSYCQKYVS QKKSNLTHWH
PVLGWFSQTV DYGLNESMPL LTKQLQHLWG VHMIRILFSD VLSKKLLENQ EIAQLPAQPV
SPQNSLPMKN LFKRAFQKSA SVRNILKPVG GKRVDSAEVQ KVCSICVLYQ TTLATLTQIR
LQILTGLTYL DDLLPKLWAF ICELGPQGGL KLFLECLNND TEESKRLLAM LMLFCDCSRH
LITILDDIEV YEEQISFKLE ELVTISSFLN SFVFKMIWDG IVENARGETL ELFHSVHGWL
MVLYERDCRR RFAPEDHWLR KDLKPSVLFQ ELDKDKKRAQ LLLQYIPHVI PHKNRVLLFR
NMVTKEKEKL GLVETSSASP HVTHITIRRQ KKKPDGYEQL RQLSQNAMKG VIRVKFVNDL
GVDEAGIDQD GVFKEFLEEI IKKVFDPALN LFKTTSGDER LYPSPTSYIH ENYLQLFEFV
GKMLGKAVYE GIVVDVPFAS FFLSQLLGHH HSVFYSSVDE LPSLDSEFYK NLTSIKRYDG
DISDLGLTLS YDEDVMGQLV CHELVPGGKT IPVTNENKIS YIHLMAHFRM HTQIKSQTAA
LISGFRSIIK PEWIRMFSAP ELQRLISGDN AEIDLEDLKK HTVYYGGFHG SHRVIIWLWD
ILANDFSPEE RAMFLKFVTS CSRPPLLGFA YLKPPFSIRC VEVSDDQDTG DTLGSVLRGF
FTIRKKEPGG RLPTSSTCFN LLKLPNYSKK SILREKLRYA ISMNTGFELS
//
