ID A0A091IQ37_EGRGA Unreviewed; 607 AA.
AC A0A091IQ37;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Mitochondrial Rho GTPase 2 {ECO:0000256|ARBA:ARBA00040475};
DE AltName: Full=Ras homolog gene family member T2 {ECO:0000256|ARBA:ARBA00042451};
DE Flags: Fragment;
GN ORFNames=Z169_01996 {ECO:0000313|EMBL:KFP09520.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP09520.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP09520.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP09520.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004200}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004200}.
CC -!- SIMILARITY: Belongs to the mitochondrial Rho GTPase family.
CC {ECO:0000256|ARBA:ARBA00007981}.
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DR EMBL; KK500657; KFP09520.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091IQ37; -.
DR STRING; 188379.A0A091IQ37; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007005; P:mitochondrion organization; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd01893; Miro1; 1.
DR CDD; cd01892; Miro2; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR013566; EF_hand_assoc_1.
DR InterPro; IPR013567; EF_hand_assoc_2.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR021181; Miro.
DR InterPro; IPR020860; MIRO_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR003578; Small_GTPase_Rho.
DR PANTHER; PTHR24072:SF311; MITOCHONDRIAL RHO GTPASE 2; 1.
DR PANTHER; PTHR24072; RHO FAMILY GTPASE; 1.
DR Pfam; PF08355; EF_assoc_1; 1.
DR Pfam; PF08356; EF_assoc_2; 1.
DR Pfam; PF00071; Ras; 1.
DR PIRSF; PIRSF037488; Mt_Rho_GTPase; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51423; MIRO; 2.
DR PROSITE; PS51419; RAB; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 581..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..157
FT /note="Miro"
FT /evidence="ECO:0000259|PROSITE:PS51423"
FT DOMAIN 293..328
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 405..568
FT /note="Miro"
FT /evidence="ECO:0000259|PROSITE:PS51423"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP09520.1"
FT NON_TER 607
FT /evidence="ECO:0000313|EMBL:KFP09520.1"
SQ SEQUENCE 607 AA; 67909 MW; 1D1CE115AAA59401 CRC64;
QVGKTSLIMA LVGEEFPEEV PPRAEEITIP ADVTPEKVPT HIVDYSVHHR DPPSPRSDAS
FLQANVVCVV YDVTKEATIE KIRTKWIPMV NGGVEKGSRI PIILVGNKSD LQVGSSMDVI
LPIMNQFSEI ETCVECSAKN LKNISELFYY AQKAVLHPTA PLYDPEEKQL KPACARALTR
IFNLSDQDNN QILSDDELNY FQKSCFGNPL APQALEDVKM VVWKNTTDGV QDNGLTLNGF
LFLNTLFIQR GRHETTWTIL RRFGYDDELE LTDDYLYPQF RLPPGCSTEL NHLGYQFLQR
LFEKHDKDQD GALSPTELQN FFSVFPCVPW GPELYNTVCT TDKGLLSLHG FLCQWTLVAY
LDVRHCLECL GYLGYPILSE QDSQTQALTV TREKRIDLEK GQTQRNVFLC KVLGARGAGK
SAFLQAFLGR SLAVQRENPG EPSLYAINTV QVNGQEKYLI LYEVSADTKF VKPSDAACDV
ACFIYDLRDP RSFSYCASLY KQHYMDSQIP CVFVASKTDL PEASQQPGLS PSQFCYKHCL
PPPFLFSCHG QGPPGTTVYT KLATAATFPH LNAVELGAAS FWLRVALGAT VTALVGFTLY
RLLAKNK
//
