ID A0A091IR03_CALAN Unreviewed; 5559 AA.
AC A0A091IR03;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Midasin {ECO:0000256|ARBA:ARBA00017143};
DE Flags: Fragment;
GN ORFNames=N300_01159 {ECO:0000313|EMBL:KFP02091.1};
OS Calypte anna (Anna's hummingbird) (Archilochus anna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes;
OC Trochilidae; Calypte.
OX NCBI_TaxID=9244 {ECO:0000313|EMBL:KFP02091.1, ECO:0000313|Proteomes:UP000054308};
RN [1] {ECO:0000313|EMBL:KFP02091.1, ECO:0000313|Proteomes:UP000054308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N300 {ECO:0000313|EMBL:KFP02091.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the midasin family.
CC {ECO:0000256|ARBA:ARBA00007188}.
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DR EMBL; KL218085; KFP02091.1; -; Genomic_DNA.
DR STRING; 9244.A0A091IR03; -.
DR Proteomes; UP000054308; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd01460; vWA_midasin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 7.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR012099; Midasin.
DR InterPro; IPR041190; Midasin_AAA_lid_5.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR Pfam; PF07728; AAA_5; 8.
DR Pfam; PF17865; AAA_lid_5; 1.
DR Pfam; PF17867; AAA_lid_7; 3.
DR PIRSF; PIRSF010340; Midasin; 2.
DR SMART; SM00382; AAA; 6.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 6.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054308}.
FT DOMAIN 5347..5546
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 483..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3524..3545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4637..5111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5130..5222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4637..4710
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4711..4725
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4726..4740
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4741..4758
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4777..4840
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4850..4868
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4869..4884
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4885..4907
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4920..4953
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4983..5000
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5030..5066
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5067..5092
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5093..5107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5162..5179
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5202..5222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP02091.1"
FT NON_TER 5559
FT /evidence="ECO:0000313|EMBL:KFP02091.1"
SQ SEQUENCE 5559 AA; 631446 MW; 943149BC082E68F0 CRC64;
QIWTPQDRQC ILDILAQLLL DKECTLLVGR QARPILLDLL ERNAESIRAG GQLNHDRHER
LCVAMSKLVA DHPDVLPFAL RYFKNTSPVF QRLFLESSDA NTVRYGRRRM KLRDLMEAAY
RFLQKEPSVF RELWDWSVCI PLLRSHDTLV RWYTSNCLAL VTCMNDEHKL SFLKKIFNPE
ELIHFRLKLL EESQLQNVEQ ALVLANPDSS FWQKEKELQY TQGHIVSGDL SANVVSVCGV
VLPRLQLVSE DQCNNSSFIF EQENNTSSFV LVESAFTNLQ NLAMAVAYQT PVLLEGPIGC
GKTSLIEYLA AVTGRAKPPH ILKVQLGDQT DSKTLLGMYR CTDLPGEFVW QPGTLTQAVT
KGHWILLEDI DYAPLDVISV LIPLLEKREL LIPGRGDCLK VATGFQFFAT RRIFSCGGGW
YRQQSSHAAL LDKYWTKIHL DNMSKGELKE VLQRRYPSLA LVTDHLLDIY IHLAGDKYQA
SENSASSCRP IPEDSSEQRS ENKKPNLEGR ELSLRDLLNW CSRIAYNFDS NSSTTAVNIF
QEALDCFTAM LSSQASRQKM AKVIGTKLNI SKKQVEFFCE LYKPEILIRE QEVSVGRVHL
VKKQIQALTA QRAKQAFAAT RPSAVLIEQL AVCVVKGEPV LLVGETGTGK TSTVQYLAHI
TGHRLRVINM NQQSDTADLL GGYKPVDNKL IWLPLRESFE ELFSQTFSRK KNQTFLGHIQ
TCYRQKRWHD LLKLMQHIHK SAINKEAKEN ASGSPLKEKW EAFGLKLNHA HQQMKMTENA
LLFAFVEGTL AQAVKKGEWV LLDEINLAAA ETLECLSGLL EGSSGSLVLL DRGDTEPLVR
HPDFRLFACM NPATDVGKRN LPPGIRNRFT ELYVEELRSE GDLQILIMDY LRGLNVNKNT
VQGIVNFYLS VRKEAEAKLV DGTGHRPHYS LRTLCRALRF AASNPCSSIQ RSLYEGFCLS
FLTQLDRSSH PVVQKLICQH IVSGNIKSLL RQQIPKPHVG RHILIEGYWI SAGDQEPAVD
ETYVLTPSVK LNLKDIARVV SAGTHPVLIQ GETSVGKTSL ILWLAAATGN HCVRINNHEH
TDIQEYIGCY TSDASGKLVF KEGILIDAMR KGYWIVLDEL NLAPTDVLEA LNRLLDDNRE
LFITETQEVV KAHPRFMLFA TQNPPGLYGG RKVLSRAFRN RFVELHFDEL PSAELETILH
KRCSLPPSYC SKLVKVMLDL QSHRRGSTVF AGKHGFITLR DLFRWAERYR LAEQLEKECD
WLQHLANDGF MLLAGRVRKQ EEVDVIQSVL EKHFKKKLYP ESLFSVESVK KLLAKSSTQM
SVMDRDFNHI VWTRGMRRLA VLVGRALEFG EAVLLVGDTG CGKTTICQIF AALTNQKLYS
VNCHLHMETS DFLGGLRPVR QRSKDQEESD GSRLFEWCDG PLVLAMKEEG FFLLDEISLA
DDSVLERLNS VLEAEKTLVL AEKGGQDDEE NEVELLVAGK KFRILATMNP GGDFGKKELS
PALRNRFTEI WCPQSNGRGD LIQIVKHNLR PGLSLRGINS QGADIAEFMM DFVEWLTNQE
FSRQCILSVR DVLSWVNFMN AMVENEESNS AKEYSLLHTS PVMSFIHAAC LVYIDGIGSG
TTSCSAETAL LAREKCLTFL CEKMSQFLEL TDYQRNELQI YDRTKKRELV WMDNFMGIHP
FFIPKGRPVL QRNSITDYAL NAGTTGVNAQ RLLRALQLNK PVLLEGSPGV GKTSLVAALA
KASGNCLVRI NLSEQTDVTD LFGTDLPVEG GKGGEFAWRD GPLLAALKAG HWIVLDELNL
ASQSVLEGLN ACFDHRAEIY VPELGMNFHV QHKKTKIFGC QNPYRQGGGR KGLPKSFLNR
FTQASSLVYV DPLSAEDMEF IGNTLFPAID RSIIAKMVDF NNKIDKEVMA EKKWGQKGGP
WEFNLRDLFR WCQLMLVDQS PGCYNPGQHV FLVYGERMRT REDKEKVIST FKDIFGQEAD
VYRGTREFHI TPYNVQIGYS ILSRGNYIPR PGRSLSLLHH SLQSLEPIMK CVHMNWMIIL
VGPAAVGKTS LVELLAHLTG HRLKIMAMNS AMDTTELLGG FEQVDINRPW QHLMEKVENA
VSTLVRDSLL LTEICADDAE LVLRAWSNFI LNYKPKSLGE GGRSITAELV SKLEGILVLM
QRMNNKINSY SKAEFAHLVE EFRRFKLQQA QVADCKSHGT FEWVDGMLVQ ALQSGDWLLM
DNVNFCNPSV LDRLNALLEP GGVLTMSERG VIDGTIPTIA PHPNFRLFLS MDPAHGEISR
AMRNRGIEIY IPGENDGTVL DNFDLKLLLH GLGLVGDSIC DALLAVHSET KAAIAGKKSS
VSSLSPLLQA AALIVQQIQR GLGLAKSFSR ACWEVYGRSQ QLQVNQKLVL ELVTKHASSL
ASHETWGDSL LAMGLWPNSL PTALFASEDS LLSTVWRDAQ VLMYCLNRLN LKNCRTLPLT
LKDLQSIIQS TNPESLKFSA VERDENWMDK MEVLQVSVKL FIEKATNQDW TLRVKWLNSL
AKNLPQVLDP VRIQLEAGAV ALGSFYASPL SSGVSNMIKL LQPTLTDEHV IPLDLRWNMQ
FLEIIRNSMN FDTEMEHADQ LQILLKSVAN RAVLFLDREK RSYTEKNLIA SKKSRNSVLR
MSLDFRKGGW ISPVHFVVVN LAAFFELWDA FLFHWVKSTQ VALSDDDTHD ILYCLLWRDR
FWAVSDTLTV DSPGLSLLSL HWHWVVKHLI DRIPQMLIGS DQHKVSREIQ SVSQQIQCCL
ANPAGIFANM KILQKSLGRP LPFKDKLGME CFSQLKVLSK PLNISELRLV FEESRWPEKM
RCLKIVATGW KMKKALLQAD GLIIRANHLE DVNLGQLNIF LKAVRSQLRA EGVVYSHSEE
RFTEDTISNQ LDSAVLNQLC SRIQLWPAME YIGMLWQYRL TADYVAKACA RRENCSQEPS
TCSDLVQLIA FSLKLTPAAS HQLSGLWHLL HLNKVSPEDM SVLSSQLVNA ALASFWSSTF
TTDPDYWLSW RPLPATEEKN FSKSHVNCSM KGPGILTRAV FSKCFFEILT SSSKTSQWDV
SGLPVLSSSH VTLGEWMERA QQLHEVNTAL WTNLAVSSIA DFRYTDTRLQ GIILGRQLSS
LVDLVPVDHQ EEFLECCEKL YLKDPIAYEY LLKILTSITD QELLPKEFLF LLLTCLQQFF
GEGLEELPET AWRGSLWVNI GLVQIQVWLP QTRFDPAVKR EYKLKYMKEE LHQVECEWKT
NDLSSQLHTG KSIEDEAISN YIHPHLRLLH ERMQRLKDQI ISLSRKKAFR PPAPPYDCLY
QEAHQYINSI ARVSSVQDLL SRLLQFLHGE RPKSLQAIQN LLNEEASWQQ SHHQFRKHLA
EEYAVFPDAI IPLQAAILQL QHGMRLVASE AYAMLKSCVH PADLTNLLTS LLTFPSVGRA
FPTYFARAEI LCSVNSVEVL RGLKKFSLKH SQVESEGAEQ PCPTLEQLLV NALLQLRCHV
LSRGDMDKES LQLFRHLCQA IINEWDEQER RAEEQEAMER SLYRYRSKSH GKGQTEEEED
EEEFRRRFPL HEKDFEDITA QPSLEEKMET EAPLEGKLEV DRALLSKSSM QTVMMVHQQL
CLNFAQSLWY RQSLPSHQAK HYFSTFISCY QTGACLVSQF YPLIGSEMND SLLGSQLLVS
TLLHNTFFEE LTSDLVLQQD GPYDFYQHPN IQQVRQCQPV LSNFSKEVNG LLQEWPEHPV
LVQLLVVMDR IRSFPLSSPL SKFLNGLEIL LAKAQDWEEN ASRALSLRKH LDLVTQLIIQ
WRRLELNCWS VSLDNIMKQH VEKSTKHWFS IYQMIEKYIQ EHTEANTEEE PMDLKTLVST
LQAFIEGSTL GEFHARLQAL LVFHCHVLLM PQVTEKDVLC SVLWNLYNYY KQFSECVKGR
ITELRQPIEK ELKEFVKISK WNDVSFWAIK QSVEKIRRTL FKFMKKFEVV LDEPCRPALV
EIGKEEQLDC LENQEESENK ETKIQRLNNT LRKTLSARTD VAKRALPEEC EDGITFHKES
LQYRLPKLTK KMKKMCATVT ENNSFLSLVE NLDQFTGGII DSVAELQNLT FDQTADKEKQ
KSEAKHIQMQ KQRALSDLFK SLAKTGLSYR KGLSWSRSKD CNEILYLHPL DLHSALGVVN
CTAELDATLL TEISSAWDGC QKYFYRSLAR HSQLQAALLA PAKDIGLRSI ERCKGFTAHL
MQTLVRQRQS LTAVTEQWIL LRNLLNCLEE IDSRLAADRE YNVAFPPQDS IQHWTDKVQQ
LSMQCVMFLE ELSWFIQCCP KEELTKCGDS ERTDVKTNVL QSSEPEMRNM FMGIPDLIPS
ELKYLSPVAT EQLPPGCRMR NKDQLWVQLA TQLTAMLTNV KAMKAEVDKI RKQSSETLLY
SWRDFEVCTS AVSCLLEVSA QLQGIESLFL PSGEDRQAAN QMTLIKSLKY IQEEVHNTSA
DFTAWREHLL ASISDGNGNQ QKDEEFVEHF SAKVETVIHL VLYAIQCLVE RKQQDGEEEE
KSPEEGKDAA SFDVIKAGHI TKLLDEDLSA DLDSLHLQKT ILAVSELLEN LKSYQKAYTS
DKHKIFNQSC YLLVRLKPML CKYSDLILFY LTVSLASHRS TGKLLSVLTS IFTELAQKGF
CLPKELLEDE AGEGATQFHD YEDGGMGDGE GQKDVSDKIE SEDQAKDSFQ KGKENEKEDQ
DSKPDIEGED NAIEMSEDFE GKMHDGEQDK QENDEDSDEE EELDKQMGNL DNAEADDKLD
ERLWGDDDED EDDEDSSSKP EETGPGMDEE DSELVAKDDN LDSGNKDNKK QPPKNEEKEQ
EEDSGNKEKI HEQIDEREYD ENEVDPYHGQ QEKEPEVEPL DLPDNLNLEN DEKSDEEGED
EGAVEKEENA FEVDEKPVDL NEAEKTEEQN EEDTGDTEID DQDAEPVEEG ASENKEEKEG
EENNDADDQE ENAGNTEDAA EEEEEESQPP DEEKNESAED KGIPAADQGL QPQEEEGQDN
SEMDEEIPKP EERMEHETQG HTGQENLQSD SAVELAGEAS ERDQSKEEYG SGAASANQSE
GHESTRMARM ASQKQSRKNT QSFKRKPGQA DNERSMGDHN EHVHKRLRTI ESSSEAKQNT
TQPKQNVEEA DAFEHIKQGS ECYDAQTYDV ASKEQEKPVM PLEEKEEGDT EDAAMETEMQ
NNEDLRAVDT EELKPEKKSN LNKAPGPVEV EPEIQTFDSE DVSDPITEKP PKLTEEKPER
RTDSTIHTAH QFLMDTPQHI VKDPEELRKE LERQLEAWQT QQSGTPDEEK EAAQLWQRYL
VLTAPLSQQL CEQLRLILEP TQAAKLKGDY RTGKRLNMRK VIPYIASQFR KDKIWLRRTK
PSKRQYQICL AIDDSSSMID NHSKQLAYES LAVIGNALTL LEVGQIAVCS FGETVQLLHP
FHEQFSDHSG TRILRLCKFQ QKKTKIAQFL ETSANMFAAA QQLSQNINPE TAQLLLIVSD
GRGLFLEGKE RVTAAVQAAQ NANIFVIFVV LDNPNSRDSI LDIKVPIFKG PGELPEIRSY
MEEFPFPFYM ILRDVNALPE TLSDALRQWF ELVTASDTL
//
