ID A0A091J1T7_EGRGA Unreviewed; 2180 AA.
AC A0A091J1T7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Unconventional myosin-VIIa {ECO:0000313|EMBL:KFP14557.1};
DE Flags: Fragment;
GN ORFNames=Z169_07749 {ECO:0000313|EMBL:KFP14557.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP14557.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP14557.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP14557.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KK501377; KFP14557.1; -; Genomic_DNA.
DR STRING; 188379.A0A091J1T7; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0120025; C:plasma membrane bounded cell projection; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd17092; FERM1_F1_Myosin-VII; 1.
DR CDD; cd17093; FERM2_F1_Myosin-VII; 1.
DR CDD; cd14473; FERM_B-lobe; 2.
DR CDD; cd13198; FERM_C1_MyoVII; 1.
DR CDD; cd13199; FERM_C2_MyoVII; 1.
DR CDD; cd01381; MYSc_Myo7; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 1.20.80.10; -; 2.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR041793; MyoVII_FERM_C1.
DR InterPro; IPR041794; MyoVII_FERM_C2.
DR InterPro; IPR036106; MYSc_Myo7.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22692; MYOSIN VII, XV; 1.
DR PANTHER; PTHR22692:SF34; MYOSIN VIIA; 1.
DR Pfam; PF00373; FERM_M; 2.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00784; MyTH4; 2.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00295; B41; 2.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50057; FERM_3; 2.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 2.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 63..739
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1015..1251
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1256..1565
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 1563..1632
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1707..1861
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1867..2170
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 2096..2123
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 616..638
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 865..933
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 156..163
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP14557.1"
FT NON_TER 2180
FT /evidence="ECO:0000313|EMBL:KFP14557.1"
SQ SEQUENCE 2180 AA; 251312 MW; 6F3799E9FD6FFE21 CRC64;
LWFQGDYVWM DLKTGREFDV PIGAVVKLCD SGQIQVVDDE GNEHWISPQN ASHIKPMHPT
SIHGVEDMIR LGDLNEAGIL RNLLIRYREH LIYTYTGSIL VAVNPYQLLP IYSPEQIRLY
TNKKIGEMPP HIFAIADNCY FNMQRNNKDQ CCIISGESGA GKTESTKLIL QFLAAISGQH
SWIEQQVLEA NPILEAFGNA KTIRNDNSSR FGKYIDIHFN KRGAIEGAKI EQYLLEKSRV
CRQAQDERNY HVFYCMLRGM TMEQKKKLGL GKATDYNYLA MGNCTTCDGR DDSKEYANIR
SAMKVLMFTD TENWEISKLL AAILHMGNLQ YEARTYDNLD ACEVVQSASL ITAASLLEVD
PQDVMNCLTS RTIITRGETV STPLSMEQAL DVRDAFVKGI YGRLFVWIVE KINAAIYRPP
SQELKSVRRS IGLLDIFGFE NFTVNSFEQL CINFANENLQ QFFVRHVFKL EQEEYNLENI
NWQHIEFTDN QDALDMIAIK PMNIISLIDE ESKFPKGTDA TMLHKLNSQH KLNTNYIPPK
NNYETQFGIN HFAGIVYYET KGFLEKNRDT LHGDIIQLVH SSKNKFIKQI FQADVAMGAE
TRKRSPTLSS QFKRSLELLM RTLSVCQPFF VRCIKPNEYK KPMLFDRELC VRQLRYSGMM
ETIRIRRAGY PIRYTFVEFV DRYRVLMPGV KPAYKQGDLR GTCQRIAEAV LGKDDDWQIG
KTKIFLKDHH DMLLEIERDK AITDKVILIQ KVVRGFKDRS NFLKVRNSAL MIQRYWRGHN
CRKNYGAMRI GFLRLQALYR SRKLHKQYHM ARRRIIEFQA RCRGYLVRRA FRHRLWAVLT
VQAYARGMIA RRLYKRLRGE YHRRLEAEKL RLAEEERLRK EMSAKKAKEE AEKKHQVRLA
QLAREDAERA VKEKEEARRK KELLEKMEKA RNEPVNDSEM VDKMFGFLGT TSSLPGQEGQ
APNGFEDLER AQKELEEEDL DAALPLPEEE EEDLSEYKFA KFAATYFQGT TTHTYIRRPL
KQPLLYHEDE GDQLAALAVW ITILRFMGDL PEPKYHTAMS DGGEKIPVMT KIYETLGKKT
YKKELQALQG EGESTHIDGH KKNSVRHKLV SLTLKKKSKL TEEVTKRLHD GESTLQGNSM
LEDRPTSNLE KLHFIIGNGI LRPALRDEIY CQICKQLTQN PSKSSHARGW ILMSLCVGCF
APSEKFVKYL RNFINGGPPG YAPYCEERLR RTFANGTRTQ PPSWLELQAT KSKKPIMLPV
TFMDGTTKTL LTDSATTAKE LCNSLADKIS LKDRFGFSLY IALFDKVSSL GSGNDHVMDA
VSQCEQYAKE QGAQERNAPW RLFFRKEIFT PWHNPSEDNV ATNLIYQQIV RGVKFGEYRC
DKEEDLAELA SQQYYVDYGS EMVLERLLNL IPSYIPDREI TASKTVEKWA QLIIAAHKKG
IYTQKRADPK KVKEEVVDFA RFKWPLLFSR FYEAFKFSGP SLPKNDVIVA VNWTGVYFVD
EQEQVLLELS FPEITAVSSS RGGKLQGQSF TLATIKGDEY TFTSNNAEDI RDLVVTFLEG
LRKRSKYVVT LQDNPNPVGE ESGFLSFLKG DLIVLDQDTG ENVMNSGWAN GFNERTKQRG
DFPTDSVYVL PTVTMPPLEI VALVTMTPDQ RQDVIRTSQM AISDSEERVK PYTLEEFSYD
YFRPPPKHTL SRVMITKSRG KDKLWCYTRE PIKQPLLKKI LGSEELSQEA CMLILDSSFP
PVLKYMGDYP SKRTRSVNEL TDQIFEGALK AEPLKDEIYC QTLKQLTDNH IKYSEEKGWE
LLWLCTGLFP PSNILLPHVQ RFLQSRKHHP LAADCIQRLQ KALRNGSRKY PPHLVEVEAI
QHKTTQIFHK VYFPDDTDEA FEVESSTKAK DFCQNISNRL LLKSSEGFSL FVKISDKVIS
VPEGDFFFDF VRHLTDWIKK ARPAKDGIVP SLTYQVFFMK KLWTNTTPGK DSMADSIFHY
YQELPKYLRG YHKCTREEVL QLAALIYRVK FEDDKSYFPS IPKLLKELVP QDLVRQLSPD
DWKRSIVAYY NKHAGKTREE AKLAFLKIIF KWPTFGSAFF EVKQTTEPNY PEILLIAINK
HGVSLIDPKT KDILITHPFT KISNWSSGNT YFHITIGNLV RGSKLLCETS LGYKMDDLLT
SYISQMLTAM SKQRSAKGSK
//
