ID A0A091J5Z8_EGRGA Unreviewed; 270 AA.
AC A0A091J5Z8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=GRHPR reductase {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=Z169_01920 {ECO:0000313|EMBL:KFP15145.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP15145.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP15145.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP15145.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; KK501480; KFP15145.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091J5Z8; -.
DR STRING; 188379.A0A091J5Z8; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR10996:SF236; 2-KETOGLUCONATE REDUCTASE; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119}.
FT DOMAIN 2..270
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 60..239
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP15145.1"
FT NON_TER 270
FT /evidence="ECO:0000313|EMBL:KFP15145.1"
SQ SEQUENCE 270 AA; 29816 MW; 17E55C2819B98F42 CRC64;
IWYHKPVINE ELLQSLPNLK IVANAGVGID NLDLNLLSSY GVKVSNTPFV VSTDTADFGM
ALMLASSRRL MEGYQMAVSP DTEYFPANWL GAEVSGATLG IVGMGTIGYK VAERAKAFEM
KILYHNRNQR NKEEESAVRA IYCKKIDDLL QQSDFVLLSV NLTPQTHKLI GKRELELMKP
TATLINISRG LVVDQDALVE ALQNKVIKAA ALDVTYPEPL PRDHTLLKLK NVIITPHIGS
ATTKTRRLMM ENMTESIQAG LTGLPIPNEV
//
