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Database: UniProt
Entry: A0A091J6F0_EGRGA
LinkDB: A0A091J6F0_EGRGA
Original site: A0A091J6F0_EGRGA 
ID   A0A091J6F0_EGRGA        Unreviewed;       431 AA.
AC   A0A091J6F0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   13-FEB-2019, entry version 13.
DE   RecName: Full=Hyaluronidase {ECO:0000256|RuleBase:RU610713};
DE            EC=3.2.1.35 {ECO:0000256|RuleBase:RU610713};
DE   AltName: Full=Hyaluronoglucosaminidase {ECO:0000256|RuleBase:RU610713};
DE   Flags: Fragment;
GN   ORFNames=Z169_13936 {ECO:0000313|EMBL:KFP15383.1};
OS   Egretta garzetta (Little egret).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX   NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP15383.1, ECO:0000313|Proteomes:UP000053119};
RN   [1] {ECO:0000313|EMBL:KFP15383.1, ECO:0000313|Proteomes:UP000053119}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP15383.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random hydrolysis of (1->4)-linkages between N-acetyl-
CC         beta-D-glucosamine and D-glucuronate residues in hyaluronate.;
CC         EC=3.2.1.35; Evidence={ECO:0000256|RuleBase:RU610713};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 56 family.
CC       {ECO:0000256|RuleBase:RU610713}.
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DR   EMBL; KK501488; KFP15383.1; -; Genomic_DNA.
DR   Proteomes; UP000053119; Unassembled WGS sequence.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR018155; Hyaluronidase.
DR   PANTHER; PTHR11769; PTHR11769; 1.
DR   Pfam; PF01630; Glyco_hydro_56; 1.
DR   PIRSF; PIRSF038193; Hyaluronidase; 1.
DR   PRINTS; PR00846; GLHYDRLASE56.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053119};
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR038193-3};
KW   Glycosidase {ECO:0000256|RuleBase:RU610713};
KW   Hydrolase {ECO:0000256|RuleBase:RU610713};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053119}.
FT   ACT_SITE    127    127       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR038193-1}.
FT   CARBOHYD    349    349       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000256|PIRSR:PIRSR038193-2}.
FT   DISULFID     39    332       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   DISULFID    203    219       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   DISULFID    357    368       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   DISULFID    362    419       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   DISULFID    421    430       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFP15383.1}.
FT   NON_TER     431    431       {ECO:0000313|EMBL:KFP15383.1}.
SQ   SEQUENCE   431 AA;  49477 MW;  C4A3E3A1EC4C3F7B CRC64;
     LAVTALLTVV DAQLPKPAQA PLVLHKPFMV VWNAPTEQCR LRYKVDLDLS VFDIASNTNE
     TLSGSNVTIF YHTHLGYYPY YSDNGDPVNG GVPQNESLIK HLNKAKSDID YCIPMKKFQG
     LAVIDWENWR PQWDRNWGNK SIYRNKSLEM VRRRHPQWSE DKIRKVAKEE FENAGKSFMN
     NTILLAEHMR PNGLWGYYLY PDCYNYDYKE HPQTYTGKCP AIESSRNDLL LWLWKESTAL
     YPSIYLDYIL KSSPNALKFV HYRVKEAIRV ASIARKDYVL PVFVYSRPFY AYTFHVLTET
     DLVNTIGESA ALGAAGVVLW GSMQYASSKE SCSTVKRYID GPLGHYVINV TSAAKLCSKV
     LCKKNGRCIR KNSDSSAYLH LSPANFKIRA RHSERGPRFQ VTGEPSLESI EAMRQRFMCQ
     CYQGWTGIFC E
//
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