ID A0A091JAV7_EGRGA Unreviewed; 376 AA.
AC A0A091JAV7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=SHC-transforming protein 1 {ECO:0000256|ARBA:ARBA00020297};
DE AltName: Full=Src homology 2 domain-containing-transforming protein C1 {ECO:0000256|ARBA:ARBA00031530};
DE Flags: Fragment;
GN ORFNames=Z169_02065 {ECO:0000313|EMBL:KFP16845.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP16845.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP16845.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP16845.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK501639; KFP16845.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091JAV7; -.
DR STRING; 188379.A0A091JAV7; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd01209; PTB_Shc; 1.
DR CDD; cd09925; SH2_SHC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006019; PID_Shc-like.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035676; SHC_SH2.
DR PANTHER; PTHR10337; SHC TRANSFORMING PROTEIN; 1.
DR PANTHER; PTHR10337:SF2; SHC-TRANSFORMING PROTEIN 1; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR PRINTS; PR00629; SHCPIDOMAIN.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Growth regulation {ECO:0000256|ARBA:ARBA00022604};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 15..126
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 282..373
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 214..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP16845.1"
FT NON_TER 376
FT /evidence="ECO:0000313|EMBL:KFP16845.1"
SQ SEQUENCE 376 AA; 41316 MW; CEA420F4C74B8638 CRC64;
RSLNSILGKS NLKFAGMPIT LTISTSSLNL MASDCKQIIA NHHMQSISFA SGGDPDTAEY
VAYVAKDPVN QRACHILECP EGLAQDVIST IGQAFELRFK QYLKNPPKLV TPHDRMAGFD
GSAWDEEEEE PAPDHQYYND FPGKEPPIGG VVDMRLREGA APTPNHLGAT LVRPWARPHG
EAPHYKGDAG TPSRPWAFGS GLFHHESHGT CLPGISSSPG SGKGWGEQRD SPPASPFSLA
QRDLFDMKPF EDALRVPASV PVGLPPAQVV ASMEEQLRRE PWYHGKMNRK EAEKLLKVNG
DFLVRESTTT PGQYVLTGLQ GGQPKHLLLV DPEGVVRTKD HRFESVSHLI SYHMDNHLPI
ISAGSEMCLQ QPVERR
//
