ID A0A091JCT2_EGRGA Unreviewed; 3014 AA.
AC A0A091JCT2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=Z169_08344 {ECO:0000313|EMBL:KFP09551.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP09551.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP09551.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP09551.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC {ECO:0000256|ARBA:ARBA00007025}.
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DR EMBL; KK500658; KFP09551.1; -; Genomic_DNA.
DR STRING; 188379.A0A091JCT2; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18668; CD1_tandem_CHD5-9_like; 1.
DR CDD; cd18663; CD2_tandem_CHD5-9_like; 1.
DR CDD; cd18059; DEXHc_CHD7; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 3.40.5.120; -; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR006576; BRK_domain.
DR InterPro; IPR037259; BRK_sf.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR46850; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9; 1.
DR PANTHER; PTHR46850:SF3; DNA HELICASE; 1.
DR Pfam; PF07533; BRK; 2.
DR Pfam; PF00385; Chromo; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00592; BRK; 2.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF160481; BRK domain-like; 2.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50013; CHROMO_2; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:KFP09551.1};
KW Helicase {ECO:0000313|EMBL:KFP09551.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 802..869
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 884..949
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 982..1156
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1296..1466
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 92..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1578..1603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1839..1870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2152..2292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2828..2903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2949..3014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..420
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..518
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..541
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..560
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..692
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..767
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 782..797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1578..1601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1854..1870
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2152..2170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2171..2241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2259..2277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2278..2292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2843..2867
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2868..2903
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2953..2987
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2990..3014
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3014 AA; 338542 MW; FA3F72DD5635224C CRC64;
MADPGMMSLF GEDGNIFSEG LEGLGECGYP ENTVNPMGQQ MPMDQGFPSL QSSLHHPPAN
QNQAKLTHFD HYNQYEQQKM HLMDQPNRMI SNAPGNGISS PHSQYHNPPV PQVPHGSGAS
GQMGVYPSMQ NERHGQPFVD SGSMWGPRAV QVPDQIRAPY QQQQQQQPQP TQPPQAPSGP
PGQGHPQHMQ QMGNYMARGD FSMQQHGQPQ QQRMNQFSQG QEGLNQGNPF IATSGPGHLS
HVPQQNPSMA PSLRHSVQQF HHHPPTALHG ESVAHSPRFS PNPPQQGAVR PQTLNFSSRS
QTVPSPTINN SGQYSRYPYS NLNQGLVNNT GMNQNLGLTN NTPMNQSVPR YPNAVGFPSN
SGQGLMHQQP IHPSGSLNQM NTQTMHPSQP QGTYASPPPM SPMKAMSNPA GTPPPQVRPG
SAGIPMEVGS YPNIPHPQPS HQPPGAMGIG QRNMGPRNMQ QNRPFMGMSS TPREMGGHMR
PNGCPGVGLA DPQAIQERLI SGQQLPSQQQ SFQQQMPTCP PMQPHPGIHH QSSPPPHPHH
QPWAQLHQSP QNTPQKVPVL QHSPSEPFLE KPVPDMTQVS GPNTQLVKSD DYLPSIEPQP
QQKKKKKKNN HIAAEGPSKG FGKEDFAGGL DNQNLSRNSV DCSQEDKKKK KKPKAKKEPK
DPKEPKEKKE PKTPKVPKTP KEPKEKKAKN TTPKPKTSKK ASNKKTDSET SAAKKKVNKG
KEGSENSDLE KTPPPSPHPE DEDDPGVQKR RSSRQVKRKR YTEDLEFKIS DEEADDADAA
GRDSPSNTSQ SEQQESADAE GPVVEKIMSS RSVKKKMENG EEVEIEEFYV KYKNFSYLHC
QWASVEELDK DKRIQQKIKR FKAKQGQNKF LSEIDDELFN PDYVEVDRIM DFSRSTDDNG
EPVMHYLVKW CSLPYEDSTW ELKQDIDQAK IEEFEKLMSR EPEIERVERP PADDWKKSES
SREYKNNNKL REYQLEGVNW LLFNWYNTRN CILADEMGLG KTIQSITFLY EIYLKGIHGP
FLVIAPLSTI PNWEREFRTW TELNVVVYHG SQASRRTIQL YEMYFKDPQG RVIKGSYKFH
AIITTFEMIL TDCPELRNIP WRCVVIDEAH RLKNRNCKLL EGLKMMDLEH KVLLTGTPLQ
NTVEELFSLL HFLEPGRFPS ETTFMQEFGD LKTEEQVQKL QAILKPMMLR RLKEDVEKNL
APKEETIIEV ELTNIQKKYY RAILEKNFTF LSKGGGQANV PNLLNTMMEL RKCCNHPYLI
NGAEEKILEE FKETHNADSP DFQLQAMIQA AGKLVLIDKL LPKLKAGGHR VLIFSQMVRC
LDILEDYLIQ RRYPYERIDG RVRGNLRQAA IDRFSRPDSD RFVFLLCTRA GGLGINLTAA
DTCIIFDSDW NPQNDLQAQA RCHRIGQSKS VKIYRLITRN SYEREMFDKA SLKLGLDKAV
LQSMSGRENA TNGVQQLSKK EIEDLLRKGA YGALMDEEDE GSKFCEEDID QILLRRTHTI
TIESEGKGST FAKASFVASG NRTDISLDDP NFWQKWAKKA ELDIDALNGR NNLVIDTPRV
RKQTRLYSAV KEDELMEFSD LESDSEEKPS TKPRRPQDKS QGYARSECFR VEKNLLVYGW
GRWTDILSHG RYKRQLTEQD VETICRTILV YCLNHYKGDE NIKSFIWDLI TPTADGQTRA
LVNHSGLSAP VPRGRKGKKV KAQSSQPMLQ DADWLTSCNP DVLFQEDSYR KHLKHHCNKV
LLRVRMLYYL RQEVIGDQAD KILEGADSSE VDIWIPEPFH AEVPADWWDK EADKSLLIGV
FKHGYEKYNS MRADPALCFL ERVGMPDAKA IAAEQRGTDM LADGGDGGEF DREDEDPEYK
PTRTPFKDEI DEFANSPPED KEESIEIHQN KHSESNAELG QLYWPNTSTL TTRLRRLITA
YQRSYKRQQM RQEALMKTDR RRRRPREEVR ALEAEREAII TEKRQKWTRR EEADFYRVVS
TFGIIFDPVK HQFDWNQFRA FARLDKKSDE SLEKYFNGFV NMCRRVCRMP VKPDDEPPDL
STMIEPITEE RASRTLYRIE LLRKIREQVL HHPQLGERLK LCQPSLDLPE WWECGKHDKD
LLVGAAKHGV SRTDYHILND PELSFLEAHK NFAQNRGTGN ANTVSSVNPL GAGCSQTPPI
VPSTPVQEEK TTEQMESKVE GSENPAAKEK SDIKEETDIA DKDTKPDCDA EAEPGSVKCE
LKDIEMSTDV DPKSISEKGS EEDEEEKLDD DDKSEESSQP EAGAVSQGKN FDEESNASMS
TARDETRDGF YMEDGDPSVV QLLHERTFAF SFWPKDRVMI NRLDNICEAV LKGKWPVNRR
QMFDFQGLIP GYTPTAVDSP LQKRSFAELS MVGQASVSGS EDITASPQLS KARLHALNLS
VPRQRRRRRR KIEIEAERAA KRRNLMEMVA QLRESQVVSE NGQEKVVDLS KASREATSST
SNFSSVTSKF ILPNVSTPVS DAFKTQMELL QAGLSRTPTR HLLNGSLIDG EPPMKRRRGR
RKNVEGLDLL FMSNKRTSLT VEDAEVTKAF EEDMEALPAR NIPSPGQLDP DTRIPVINLE
DGTRLVGEDA PKNKDLVEWL KLHPTYTVDM PSYVPKSADV LFSPFQKPKQ KRHRCRNPNK
LDINTLTGEE RVPVVNKRNG KKMGGAMAPP MKDLPRWLEE NPEFAVAPDW TDIVKQSGFV
PESMFDRLLT GPVVREEGAS RRGRRPKSEI AKAAAAAAAV ASTSGINPLL MNSLFAGMDL
TSLQNLQNLQ SLQLAGLMGF PPGLATAAAA GGDTKNPAAM LPLMLPGMAG LPNMFGLSGL
LNNPITATTG NATTASGQGE TEDGASKAEE KKNENEEENK DSEKSTDAVS ATDSANGSVS
AATAATTATA TTTTTTNTGL PTNPLAFNPF LLSTMAPGLF YPSMFLPPGL GGLTLPGFPA
LAGLQNTVGS NEEKATDKTE GTAFKDEENL EGSDAEESLD KTADSSVLED EIAQGEELDS
LDGGEEIENN ENDE
//
