ID A0A091JF69_EGRGA Unreviewed; 966 AA.
AC A0A091JF69;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Alanine--tRNA ligase {ECO:0000256|ARBA:ARBA00017959};
DE EC=6.1.1.7 {ECO:0000256|ARBA:ARBA00013168};
DE Flags: Fragment;
GN ORFNames=Z169_06093 {ECO:0000313|EMBL:KFP19664.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP19664.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP19664.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP19664.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Alax-L subfamily. {ECO:0000256|ARBA:ARBA00008429}.
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DR EMBL; KK502030; KFP19664.1; -; Genomic_DNA.
DR RefSeq; XP_009641635.1; XM_009643340.1.
DR AlphaFoldDB; A0A091JF69; -.
DR STRING; 188379.A0A091JF69; -.
DR GeneID; 104130306; -.
DR KEGG; egz:104130306; -.
DR CTD; 16; -.
DR OrthoDB; 3639120at2759; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00673; AlaRS_core; 1.
DR Gene3D; 2.40.30.130; -; 1.
DR Gene3D; 3.10.310.40; -; 1.
DR HAMAP; MF_00036_B; Ala_tRNA_synth_B; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002318; Ala-tRNA-lgiase_IIc.
DR InterPro; IPR018162; Ala-tRNA-ligase_IIc_anticod-bd.
DR InterPro; IPR018165; Ala-tRNA-synth_IIc_core.
DR InterPro; IPR018164; Ala-tRNA-synth_IIc_N.
DR InterPro; IPR023033; Ala_tRNA_ligase_euk/bac.
DR InterPro; IPR003156; DHHA1_dom.
DR InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR012947; tRNA_SAD.
DR NCBIfam; TIGR00344; alaS; 1.
DR PANTHER; PTHR11777:SF36; ALANINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR11777; ALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF02272; DHHA1; 1.
DR Pfam; PF01411; tRNA-synt_2c; 1.
DR Pfam; PF07973; tRNA_SAD; 1.
DR PRINTS; PR00980; TRNASYNTHALA.
DR SMART; SM00863; tRNA_SAD; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF101353; Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS); 1.
DR SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS50860; AA_TRNA_LIGASE_II_ALA; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KFP19664.1};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 5..766
FT /note="Alanyl-transfer RNA synthetases family profile"
FT /evidence="ECO:0000259|PROSITE:PS50860"
FT NON_TER 966
FT /evidence="ECO:0000313|EMBL:KFP19664.1"
SQ SEQUENCE 966 AA; 106460 MW; 6B49948505BB4E9C CRC64;
MEATLTASQI RQRFIDFFKA NKHTYVHSSS TIPLDDPTLL FANAGMNQFK PIFLNTIDPS
HPLAKLNRAT NTQKCIRAGG KHNDLDDVGK DVYHHTFFEM LGSWSFGDYF KELACKLALD
LLTKEFGIPA DRLYVTYFGG NEAAGLQPDL ECKQIWLNLG LAEGRILPGN MKDNFWEMGD
TGPCGPCSEI HYDRIGDRDA SHLVNQDDPN VLEIWNLVFI QFNREADGTL KPLPKKSIDT
GMGLERLVSV LQNKMSNYDT DLFLPYFEAI QKGTGARPYM GKVGAEDADG IDMAYRVLAD
HARTITLALS DGGRPDNTGR GYVLRRILRR AVRYSHEKLN APKGFFASLV DVVVQSLGDA
FPELKKDPDM VKDIINEEED QFLKTLSRGR RILDRKIQSL GDSKTIPGDT AWLLYDTYGF
PVDLTGLIAE EKGLVVDMEG FEEERKNAQL KSQGKGAGGE DLLMLDIYAI EELRARGLEV
TDDSPKYSYA SDQSGAYDFG SLVATVKAIR REKKFVEEVS TGQECGIVLD RTCFYAEQGG
QIYDEGYMVK DDDGREDKTE FTVKNVQVRG GYVLHIGTLY GSLKVGDQVQ LSIDEARRGP
GMSNHTATHI LNFALRSVLG EADQRGSLVA PDRLRFDFTA KGALSTQEIK KVEGIANQMI
EEAKTVYAKD CPLAAAKAIQ GLRAVFDETY PDPVRVVSIG IPVEELLADP SGPAGSITSI
EFCGGTHLQN SSHAGPFVIV SEEAIAKGIR RIVAVTGAEA RKALRKVDSL RKLLSALEAK
VKVQTAPNKD LQKEIADLSE TLATAVIPQW QKDELREAVK ALKKVMDDLD RASKADIQKR
VLEKTKQVIE SHPNQPLVIM EMENGASAKA LNESLKLFKT HSPQTATMLF AVDNEAGRIT
CLCQVPQETA NKGLKASQWV QEVSGLMDGK GGGKDISAQA TGKNVGCLRE ALKLATDFAR
LRLGEL
//
