ID A0A091JHI6_EGRGA Unreviewed; 689 AA.
AC A0A091JHI6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 33.
DE SubName: Full=Neurofilament heavy polypeptide {ECO:0000313|EMBL:KFP19358.1};
DE Flags: Fragment;
GN ORFNames=Z169_14618 {ECO:0000313|EMBL:KFP19358.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP19358.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP19358.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP19358.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KK501992; KFP19358.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091JHI6; -.
DR STRING; 188379.A0A091JHI6; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0005883; C:neurofilament; IEA:InterPro.
DR GO; GO:0061564; P:axon development; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR033183; NF-H.
DR PANTHER; PTHR23214:SF1; NEUROFILAMENT HEAVY POLYPEPTIDE; 1.
DR PANTHER; PTHR23214; NEUROFILAMENT TRIPLET H PROTEIN; 1.
DR Pfam; PF00038; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119}.
FT DOMAIN 1..118
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 41..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..200
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..515
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP19358.1"
FT NON_TER 689
FT /evidence="ECO:0000313|EMBL:KFP19358.1"
SQ SEQUENCE 689 AA; 75371 MW; 43B2465DCC42B343 CRC64;
RLDKLSEVAK VNTDAIRLAQ EEICEYRRQL QSKTTELEAL KGTQESLERQ RQDSEERHHA
DVLSYQETIQ QLDSELRNTK WEMAAQLREY QDLLNVKMAL DIEIAAYRKL LEGEEYRIES
GFGMVSFPEV VPKAPSITTD IKVKSEEKIK VVEKSEKETV IVEEQTEEIQ VTEEVTEEEE
AEKEVEEEEK KEEEKDEAEG EEEAKSPAKE EAKSPEKPKS PSKEEAKSPP VKSPEKPPTP
SKEEAKSPAV KSPEKPTPPS KEEAKSPAVK SPEKPATPSK EEAKSSAVKS PEKPATPSKE
EAKSSAVKSP EKPPTPSKEE AKSPAVKSPE KPATPSKEEA KTPSVKSPEK PPTPAKEEAK
SPAVKSPEKP PTPSKEEAKT PAVKSPEKPP TPSKEETKPP AVKSPEKPAP PSKEEAKSPP
VKSPEKPPTP SKEEVKPPAV KSPEKPAAPS KEEAKTPSVK SPEKPPTPSK EEAKSPAVKS
PEKPPTPSKE EAKTVKSPEK VKSPMKEEAK SPQKEAAPAK EPTPSPLKEP KGPVKEEQPK
EVKAPSKPRA EEGRKEEAPK KDIPAKMEEK PKEKVTAGLE PAAPQVKETT KPGPKPTEEG
KAEKEAPPKP QQEVGKVAVK EAEKPKAKEK VEEPKKEKVE EPKKEKVEEP KAKAKPKDEP
QASKEPAKAE APSSKESKAP EPAPAVGKK
//
