ID A0A091JI44_EGRGA Unreviewed; 667 AA.
AC A0A091JI44;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=Z169_14138 {ECO:0000313|EMBL:KFP20699.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP20699.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP20699.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP20699.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK502100; KFP20699.1; -; Genomic_DNA.
DR RefSeq; XP_009642815.1; XM_009644520.1.
DR AlphaFoldDB; A0A091JI44; -.
DR STRING; 188379.A0A091JI44; -.
DR GeneID; 104131361; -.
DR KEGG; egz:104131361; -.
DR CTD; 56924; -.
DR OrthoDB; 460351at2759; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01093; CRIB_PAK_like; 1.
DR CDD; cd06659; STKc_PAK6; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR033923; PAK_BD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR035066; STKc_PAK6.
DR PANTHER; PTHR48015; SERINE/THREONINE-PROTEIN KINASE TAO; 1.
DR PANTHER; PTHR48015:SF19; SERINE_THREONINE-PROTEIN KINASE PAK 6; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00285; PBD; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:KFP20699.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Transferase {ECO:0000313|EMBL:KFP20699.1}.
FT DOMAIN 12..25
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 393..644
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 422
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 667 AA; 74672 MW; 1DC4A4DA5BEDA4FE CRC64;
MFRKKKKKRP EISAPQNFEH RVHTSFDPKE GKFVGLPPQW QNILDTLRRP KPVVEGIRGR
LLLPLGFPTV VRGSTVEVEG YISGILNDIQ KLSAISSNTL RGRSPTSRRR AQSLGLLGED
RPPDMYLQSP EADWADKYGN YLNCNGGTKV TRRQTMWPDY KPRLEGQSHP NGMVMKAQSL
GPSEFQGADS TCLQRASGLQ HMPTLPGESE KTGKRSSEEC WPQPCLIRQA NSRPSGEGSP
SSKSRENSLK RRLLRSVFPS SSGSNKSGPS LQIKPNTFFR PQQWGSPRSP AAKAQSLPPD
QPASDFPRMT SEAGTPQKSP TVEKAIALPQ GRPSPAGSPR NRQTQTSSSN LHLPQDSSVK
GQLASEDPVV VTHEQFKAAL RMVVDQGDPR TLLENYVKIG EGSTGIVCIA REKHSGRQVA
VKMMDLRKQQ RRELLFNEVV IMRDYQHVNV VEMYKSYLVG EELWVLMEFL QGGALTDIVS
QIRLNEEQIA TVCESVLQAL SYLHSQGVIH RDIKSDSILL TLDGRVKLSD FGFCAQISKD
VPKRKSLVGT PYWMAPEVIA RIPYATEVDI WSLGIMVIEM VDGEPPYFSD SPVQAMKRLR
DSPPPKLKNF HRTSPVLRDF LERMLTRDPL ERATAQELLD HPFLLQTGLP ECLVPLIQQY
RKRTSTC
//
