ID   A0A091JKF4_EGRGA        Unreviewed;       974 AA.
AC   A0A091JKF4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 29.
DE   SubName: Full=Huntingtin-interacting protein 1 {ECO:0000313|EMBL:KFP21067.1};
DE   Flags: Fragment;
GN   ORFNames=Z169_00516 {ECO:0000313|EMBL:KFP21067.1};
OS   Egretta garzetta (Little egret).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX   NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP21067.1, ECO:0000313|Proteomes:UP000053119};
RN   [1] {ECO:0000313|EMBL:KFP21067.1, ECO:0000313|Proteomes:UP000053119}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP21067.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the SLA2 family.
CC       {ECO:0000256|ARBA:ARBA00010135}.
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DR   EMBL; KK502172; KFP21067.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091JKF4; -.
DR   STRING; 188379.A0A091JKF4; -.
DR   Proteomes; UP000053119; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   Gene3D; 1.20.5.1700; -; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   Gene3D; 6.10.250.920; -; 1.
DR   Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR   InterPro; IPR011417; ANTH_dom.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR032422; HIP1_clath-bd.
DR   InterPro; IPR035964; I/LWEQ_dom_sf.
DR   InterPro; IPR002558; ILWEQ_dom.
DR   InterPro; IPR030224; Sla2_fam.
DR   PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR10407:SF14; HUNTINGTIN-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF07651; ANTH; 1.
DR   Pfam; PF16515; HIP1_clath_bdg; 1.
DR   Pfam; PF01608; I_LWEQ; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00307; ILWEQ; 1.
DR   SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR   SUPFAM; SSF109885; I/LWEQ domain; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50945; I_LWEQ; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053119}.
FT   DOMAIN          1..116
FT                   /note="ENTH"
FT                   /evidence="ECO:0000259|PROSITE:PS50942"
FT   DOMAIN          723..964
FT                   /note="I/LWEQ"
FT                   /evidence="ECO:0000259|PROSITE:PS50945"
FT   REGION          452..473
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          502..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          930..959
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        456..473
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFP21067.1"
FT   NON_TER         974
FT                   /evidence="ECO:0000313|EMBL:KFP21067.1"
SQ   SEQUENCE   974 AA;  108371 MW;  65193EF565D5099F CRC64;
     QTVSINKAIN AQEVAVKEKH ARNILPEAGC RTNELVNRLP LSGNAVLCWK FCHVFHKLLR
     DGHSNVLKDS VRYKNELSDM SRMWGHLSEG YGQLCSIYLK LLRTKMEFHT KNPRFPGNLQ
     MSDRQLDEAG ENDVNNFFQL TVEMFDYLEC ELNLFQTVFS SLDMSRSVSV TAAGQCRLAP
     LIQVILDCSH LYDYTVKLLF KLHSCLPADT LQGHRDRFLE QFRKLKDLFY RSSNLQYFKR
     LIQIPQLPEN PPNFLRASAL SEHISPVVVI PAEASSPDSE PITDLVEMDT ASQSLFDNKF
     DDIFGSSFNS DPFNFNSQNG MKKDDKDRLI EQLYGEIAAL KEELENFKAE SARGVVQLRG
     RASELEAELA EQRHLKQQAQ DESEFLRTEL EELKKQREDT EKAQRSLTEI ERRAQANEQR
     YSKLKEKYSE LVQNHADLLR KNAEVTKQVT AARQAQGDVE REKKELEDSF QRSQEQAEVL
     DTLKREVAAS RQELQVLQGT LESSAQAGAE QSTRIAGLEQ ERDSLSRAAE RHGEEMAALR
     AELQGLREVL SLGAVTPALA WQESGEQALQ RRLAEEQFAL LRGTAREAER MVQDAPRLSP
     ACCLPADCLL SRTLAASECV ERLRDAHGKY LSNCAAMGSL LPCLALFAHL VSDTLLQGSA
     TSHVAPMEPA DRLLEMCKQC GSEAVSYLSA LQDPGTVESA DCSPVTACLG RISTIGEELR
     PRGLDVKQEE LGDLVDKEMA ATAAAIETAS ARIEEMLSKA RAGDTGVKLE VNERILGSCT
     GLMQAIHILV LASKDLQREI VESGRGAASP KEFYAKNSRW TEGLISASKA VGWGATVMVD
     AADLVVQGKG TFEELMVCSR EIAASTAQLV AASKVKADKD STNLCKLQQA SRGVNQATAG
     VVASTKAGKS QVEEKDSMDF SSMTLTQIKR QEMDSQVRVL ELENQLQKER QKLGELRKKH
     YELAGVAEGW EEDG
//